Drug Interactions between cedazuridine / decitabine and lyme disease vaccine
This report displays the potential drug interactions for the following 2 drugs:
- cedazuridine/decitabine
- lyme disease vaccine
Interactions between your drugs
Lyme disease vaccine decitabine
Applies to: lyme disease vaccine and cedazuridine / decitabine
GENERALLY AVOID: The administration of Lyme disease vaccine to immunosuppressed patients may be associated with a diminished or suboptimal immunologic response due to antibody inhibition. Such patients may include those who have recently received or are receiving immunosuppressive agents, antilymphocyte globulins, alkylating agents, antimetabolites, radiation, some antirheumatic agents, high dosages of corticosteroids or adrenocorticotropic agents (greater than 10 mg/day to 1 mg/kg/day, whichever is less, of prednisone or equivalent for more than 2 weeks), or long-term topical or inhaled corticosteroids.
MANAGEMENT: The manufacturer suggests considering deferral of vaccination against Lyme disease until 3 months after discontinuation of immunosuppressive therapy. Vaccines may generally be administered to patients receiving corticosteroids as replacement therapy (e.g., for Addison's disease).
References
- "Product Information. LYMErix (Lyme disease vaccine)." SmithKline Beecham
Drug and food interactions
cedazuridine food
Applies to: cedazuridine / decitabine
ADJUST DOSING INTERVAL: There are no data regarding the concurrent administration of oral cedazuridine-decitabine with food.
MANAGEMENT: The manufacturer recommends that patients avoid eating for 2 hours before and 2 hours after administration of oral cedazuridine-decitabine.
References
- (2020) "Product Information. Inqovi (cedazuridine-decitabine)." Taiho Oncology, Inc.
Therapeutic duplication warnings
No warnings were found for your selected drugs.
Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.
See also
Drug Interaction Classification
Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
No interaction information available. |
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
Check Interactions
To view an interaction report containing 4 (or more) medications, please sign in or create an account.
Save Interactions List
Sign in to your account to save this drug interaction list.