Drug Interactions between Bactrim and Rezurock
This report displays the potential drug interactions for the following 2 drugs:
- Bactrim (sulfamethoxazole/trimethoprim)
- Rezurock (belumosudil)
Interactions between your drugs
No interactions were found between Bactrim and Rezurock. However, this does not necessarily mean no interactions exist. Always consult your healthcare provider.
Bactrim
A total of 412 drugs are known to interact with Bactrim.
- Bactrim is in the drug class sulfonamides.
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Bactrim is used to treat the following conditions:
- Bacterial Infection
- Bacterial Skin Infection
- Bronchitis
- Diverticulitis
- Epiglottitis
- Granuloma Inguinale
- Infection Prophylaxis
- Kidney Infections
- Melioidosis
- Meningitis
- Middle Ear Infections
- Nocardiosis
- Pneumocystis Pneumonia
- Pneumocystis Pneumonia Prophylaxis
- Pneumonia
- Prevention of Bladder infection
- Prostatitis
- Shigellosis
- Sinusitis
- Toxoplasmosis
- Toxoplasmosis, Prophylaxis
- Traveler's Diarrhea
- Upper Respiratory Tract Infection
- Urinary Tract Infection
Rezurock
A total of 130 drugs are known to interact with Rezurock.
- Rezurock is in the drug class selective immunosuppressants.
- Rezurock is used to treat Graft-versus-host disease.
Drug and food interactions
belumosudil food
Applies to: Rezurock (belumosudil)
Consumer information for this interaction is not currently available.
ADJUST DOSING INTERVAL: Administration with food increases the oral bioavailability of belumosudil. The mechanism has not been described. Administration of belumosudil (200 mg single oral dose) in healthy subjects, with a fatty and calorie-rich meal (approximately half of the calories were contained in the fat) increased the mean belumosudil peak plasma concentration (Cmax) and area under the concentration-time curve (AUC) by 120% and 100%, respectively, compared to administration under fasting conditions. The time to reach peak concentration (Tmax) was delayed by 30 minutes. Administration of oral belumosudil 200 mg once daily with food in patients with chronic graft-versus-host disease (chronic GVHD) lead to steady-state concentrations of the drug with an accumulation ration of 1.4.
MANAGEMENT: To ensure maximal oral absorption, belumosudil should be administered with a meal, every day at the same time.
References
- (2024) "Product Information. Rezurock (belumosudil)." Sanofi
- (2024) "Product Information. Rezurock (belumosudil)." Kadmon Pharmaceuticals, 11/2023
sulfamethoxazole food
Applies to: Bactrim (sulfamethoxazole / trimethoprim)
Ask your doctor before using sulfamethoxazole together with ethanol. Contact your doctor if you experience unpleasant side effects such as fast heartbeats, warmth or redness under your skin, tingly feeling, nausea, or vomiting. If you experience these side effects, you may need to avoid ethanol while taking sulfamethoxazole. You should check your food and medicine labels to see if these products contain ethanol. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Therapeutic duplication warnings
No warnings were found for your selected drugs.
Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.
See also
Drug Interaction Classification
Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
No interaction information available. |
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
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