Drug Interactions between Aminatal Plus and dimercaprol
This report displays the potential drug interactions for the following 2 drugs:
- Aminatal Plus (multivitamin, prenatal)
- dimercaprol
Interactions between your drugs
dimercaprol multivitamin, prenatal
Applies to: dimercaprol and Aminatal Plus (multivitamin, prenatal)
ADJUST DOSING INTERVAL: Dimercaprol can form a nephrotoxic chelate with certain metals such as cadmium, iron, and selenium.
MANAGEMENT: Preparations containing iron or selenium salts should not be administered during chelation therapy with dimercaprol and for at least 24 hours after the last dose of dimercaprol.
References
- Seffart G ed. (1991) "Drug Dosage in Renal Insufficiency." Dordrecht, South Holland, : Kluwer Academic Publishers
- Chenoweth MB (1968) "Clinical uses of metal-binding drugs." Clin Pharmacol Ther, 9, p. 365-87
- (2022) "Product Information. BAL In Oil (dimercaprol)." Apothecon Inc
Drug and food interactions
dimercaprol food
Applies to: dimercaprol
ADJUST DOSING INTERVAL: Dimercaprol can form a nephrotoxic chelate with certain metals such as cadmium, iron, and selenium.
MANAGEMENT: Preparations containing iron or selenium salts should not be administered during chelation therapy with dimercaprol and for at least 24 hours after the last dose of dimercaprol.
References
- Seffart G ed. (1991) "Drug Dosage in Renal Insufficiency." Dordrecht, South Holland, : Kluwer Academic Publishers
- Chenoweth MB (1968) "Clinical uses of metal-binding drugs." Clin Pharmacol Ther, 9, p. 365-87
- (2022) "Product Information. BAL In Oil (dimercaprol)." Apothecon Inc
multivitamin, prenatal food
Applies to: Aminatal Plus (multivitamin, prenatal)
ADJUST DOSING INTERVAL: Concomitant use of some oral medications may reduce the bioavailability of orally administered iron, and vice versa.
Food taken in conjunction with oral iron supplements may reduce the bioavailability of the iron. However, in many patients intolerable gastrointestinal side effects occur necessitating administration with food.
MANAGEMENT: Ideally, iron products should be taken on an empty stomach (i.e., at least 1 hour before or 2 hours after meals), but if this is not possible, administer with meals and monitor the patient more closely for a subtherapeutic effect. Some studies suggest administration of iron with ascorbic acid may enhance bioavailability. In addition, administration of oral iron products and some oral medications should be separated whenever the bioavailability of either agent may be decreased. Consult the product labeling for specific separation times and monitor clinical responses as appropriate.
References
- "Product Information. Feosol (ferrous sulfate)." SmithKline Beecham
- (2021) "Product Information. Accrufer (ferric maltol)." Shield Therapeutics
Therapeutic duplication warnings
No warnings were found for your selected drugs.
Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.
See also
Drug Interaction Classification
Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
No interaction information available. |
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
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