Skip to main content

Drug Interactions between Aminatal Plus and dimercaprol

This report displays the potential drug interactions for the following 2 drugs:

Edit list (add/remove drugs)

Interactions between your drugs

Major

dimercaprol multivitamin, prenatal

Applies to: dimercaprol and Aminatal Plus (multivitamin, prenatal)

ADJUST DOSING INTERVAL: Dimercaprol can form a nephrotoxic chelate with certain metals such as cadmium, iron, and selenium.

MANAGEMENT: Preparations containing iron or selenium salts should not be administered during chelation therapy with dimercaprol and for at least 24 hours after the last dose of dimercaprol.

References

  1. Seffart G ed. (1991) "Drug Dosage in Renal Insufficiency." Dordrecht, South Holland, : Kluwer Academic Publishers
  2. Chenoweth MB (1968) "Clinical uses of metal-binding drugs." Clin Pharmacol Ther, 9, p. 365-87
  3. (2022) "Product Information. BAL In Oil (dimercaprol)." Apothecon Inc

Switch to consumer interaction data

Drug and food interactions

Major

dimercaprol food

Applies to: dimercaprol

ADJUST DOSING INTERVAL: Dimercaprol can form a nephrotoxic chelate with certain metals such as cadmium, iron, and selenium.

MANAGEMENT: Preparations containing iron or selenium salts should not be administered during chelation therapy with dimercaprol and for at least 24 hours after the last dose of dimercaprol.

References

  1. Seffart G ed. (1991) "Drug Dosage in Renal Insufficiency." Dordrecht, South Holland, : Kluwer Academic Publishers
  2. Chenoweth MB (1968) "Clinical uses of metal-binding drugs." Clin Pharmacol Ther, 9, p. 365-87
  3. (2022) "Product Information. BAL In Oil (dimercaprol)." Apothecon Inc

Switch to consumer interaction data

Moderate

multivitamin, prenatal food

Applies to: Aminatal Plus (multivitamin, prenatal)

ADJUST DOSING INTERVAL: Concomitant use of some oral medications may reduce the bioavailability of orally administered iron, and vice versa.

Food taken in conjunction with oral iron supplements may reduce the bioavailability of the iron. However, in many patients intolerable gastrointestinal side effects occur necessitating administration with food.

MANAGEMENT: Ideally, iron products should be taken on an empty stomach (i.e., at least 1 hour before or 2 hours after meals), but if this is not possible, administer with meals and monitor the patient more closely for a subtherapeutic effect. Some studies suggest administration of iron with ascorbic acid may enhance bioavailability. In addition, administration of oral iron products and some oral medications should be separated whenever the bioavailability of either agent may be decreased. Consult the product labeling for specific separation times and monitor clinical responses as appropriate.

References

  1. "Product Information. Feosol (ferrous sulfate)." SmithKline Beecham
  2. (2021) "Product Information. Accrufer (ferric maltol)." Shield Therapeutics

Switch to consumer interaction data

Therapeutic duplication warnings

No warnings were found for your selected drugs.

Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.


Report options

Loading...
QR code containing a link to this page

Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.