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Drug Interactions between Alphanine SD and pegloticase

This report displays the potential drug interactions for the following 2 drugs:

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Interactions between your drugs

Moderate

coagulation factor IX pegloticase

Applies to: Alphanine SD (coagulation factor ix) and pegloticase

Treatment with pegloticase may cause coagulation factor IX to be less effective in some cases. Many patients treated with pegloticase develop antibodies against one of the components that is also found in coagulation factor IX. High levels of the antibodies have been associated with reduced effectiveness of pegloticase, so it is possible that they may also interfere with the effects of coagulation factor IX. Contact your doctor if your symptoms worsen during treatment with these medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Drug and food interactions

No alcohol/food interactions were found. However, this does not necessarily mean no interactions exist. Always consult your healthcare provider.

Therapeutic duplication warnings

No warnings were found for your selected drugs.

Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.

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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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