Drug Interactions between Afinitor and temsirolimus
This report displays the potential drug interactions for the following 2 drugs:
- Afinitor (everolimus)
- temsirolimus
Interactions between your drugs
No interactions were found between Afinitor and temsirolimus. However, this does not necessarily mean no interactions exist. Always consult your healthcare provider.
Afinitor
A total of 516 drugs are known to interact with Afinitor.
- Afinitor is in the following drug classes: mTOR inhibitors, selective immunosuppressants.
- Afinitor is used to treat the following conditions:
temsirolimus
A total of 674 drugs are known to interact with temsirolimus.
- Temsirolimus is in the drug class mTOR inhibitors.
- Temsirolimus is used to treat Renal Cell Carcinoma.
Drug and food interactions
everolimus food
Applies to: Afinitor (everolimus)
Grapefruit juice can increase the blood levels and effects of everolimus. You should not drink grapefruit juice or eat grapefruits during your treatment with everolimus. Orange juice is not expected to interact.
temsirolimus food
Applies to: temsirolimus
If you are receiving therapy with temsirolimus you should avoid grapefruits and grapefruit juice. Grapefruit can raise the levels of temsirolimus in your body and lead to dangerous side effects. Do not increase or decrease the amount of grapefruit products in your diet without first talking to your doctor.
Therapeutic duplication warnings
Therapeutic duplication is the use of more than one medicine from the same drug category or therapeutic class to treat the same condition. This can be intentional in cases where drugs with similar actions are used together for demonstrated therapeutic benefit. It can also be unintentional in cases where a patient has been treated by more than one doctor, or had prescriptions filled at more than one pharmacy, and can have potentially adverse consequences.
Macrolide immunosuppressants
Therapeutic duplication
The recommended maximum number of medicines in the 'macrolide immunosuppressants' category to be taken concurrently is usually one. Your list includes two medicines belonging to the 'macrolide immunosuppressants' category:
- Afinitor (everolimus)
- temsirolimus
Note: In certain circumstances, the benefits of taking this combination of drugs may outweigh any risks. Always consult your healthcare provider before making changes to your medications or dosage.
Mtor inhibitors
Therapeutic duplication
The recommended maximum number of medicines in the 'mTOR inhibitors' category to be taken concurrently is usually one. Your list includes two medicines belonging to the 'mTOR inhibitors' category:
- Afinitor (everolimus)
- temsirolimus
Note: In certain circumstances, the benefits of taking this combination of drugs may outweigh any risks. Always consult your healthcare provider before making changes to your medications or dosage.
See also
Drug Interaction Classification
Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
No interaction information available. |
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
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