Drug Interactions

Drug interactions between Abraxane and dexamethasone

Results for the following 2 drugs:

Abraxane (paclitaxel protein-bound)
dexamethasone

Interactions between your selected drugs

dexamethasone ⇔ paclitaxel protein-bound

Applies to: dexamethasone and Abraxane (paclitaxel protein-bound)

MONITOR: Theoretically, coadministration with drugs that are inducers of CYP450 2C8 and/or 3A4 may decrease the plasma concentrations of paclitaxel, which is metabolized by these isoenzymes.

MANAGEMENT: Clinicians should recognize the potential for interaction with drugs that induce CYP450 2C8 and/or 3A4 and monitor for evidence of reduced therapeutic response to paclitaxel during coadministration.

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