Zolinza Dosage
Generic name: vorinostat
Dosage form: capsule
This dosage information does not include all the information needed to use Zolinza safely and effectively. See full prescribing information for Zolinza.
The information at Drugs.com is not a substitute for medical advice. ALWAYS consult your doctor or pharmacist.
Dosing Information
The recommended dose is 400 mg orally once daily with food.
Treatment may be continued as long as there is no evidence of progressive disease or unacceptable toxicity.
ZOLINZA capsules should not be opened or crushed [see How Supplied/Storage and Handling (16)].
Dose Modifications
If a patient is intolerant to therapy, the dose may be reduced to 300 mg orally once daily with food. The dose may be further reduced to 300 mg once daily with food for 5 consecutive days each week, as necessary.
Dosing in Special Populations
​ZOLINZA is contraindicated in patients with severe hepatic impairment [see Contraindications (4), Warnings and Precautions (5.4), Use in Specific Populations (8.6) and Clinical Pharmacology (12.3)].
No information is available in patients with renal impairment [see Clinical Pharmacology (12.3)].
