This dosage information may not include all the information needed to use Teduglutide safely and effectively. See additional information for Teduglutide.
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Usual Adult Dose for:
Additional dosage information:
Usual Adult Dose for Short Bowel Syndrome
In Patients Dependent on Parenteral Support:
0.05 mg/kg body weight subcutaneously once daily
Comments: Rotation of injection sites recommended (thighs, arms, and quadrants of the abdomen)
Renal Dose Adjustments
Mild renal dysfunction: No adjustment recommended.
Moderate to severe renal dysfunction (CrCl less than 50 mL/min) and end-stage renal disease: Reduce dose by 50%
Liver Dose Adjustments
Mild to moderate liver dysfunction (Child-Pugh B): No adjustment recommended.
Severe liver dysfunction (Child-Pugh C): Data not available
Consult WARNINGS section for dosing related precautions.
Data not available
-Not for intravenous or intramuscular use
-Drug should be completely dissolved prior to withdrawing from vial.
-Use within 3 hours of reconstitution.
-Do not shake or freeze reconstituted solution.
-Discard any unused portion.
-Prior to dispensing: Refrigerate vials and one-vial kits. Do not freeze.
Reconstitution/preparation techniques: The manufacturer's product information should be consulted.
-Subcutaneous administration can cause injection site reactions
-Abdominal pain and swelling of stoma may occur when starting treatment
-Report any symptoms of intestinal obstruction, pancreatic disease, gallbladder and bile duct disease, and fluid overload or cardiac decompensation
-Report any concomitant oral medications, especially benzodiazepines and psychotropic agents