Risedronate Dosage

This dosage information may not include all the information needed to use Risedronate safely and effectively. See additional information for Risedronate.

The information at Drugs.com is not a substitute for medical advice. ALWAYS consult your doctor or pharmacist.

Usual Adult Dose for:

Additional dosage information:

Usual Adult Dose for Paget's Disease

30 mg orally once a day. Therapy should be continued for 2 months. A drug free interval of at least 2 months should be allowed to assess response. Retreatment may be considered after a 2 month period for patients who have relapsed or did not respond based on a failure to normalize serum alkaline phosphatase levels. Data are not available regarding more than one course of treatment.

Usual Adult Dose for Osteoporosis

For prevention or treatment of postmenopausal osteoporosis: 5 mg orally once daily or 35 mg orally once a week. Also, risedronate 75 mg may be given orally once a day on two consecutive days, for a total of two tablets monthly. Additionally, risedronate 150 mg may be given orally once a month.

For treatment of osteoporosis in men: 35 mg orally once a week.

For prevention or treatment of glucocorticoid induced osteoporosis: 5 mg orally once daily.

Patients should receive adequate supplements of calcium and vitamin D.

Patients should be instructed that if they miss a dose of risedronate 35 mg once a week, they should take 1 tablet on the morning after they remember and return to taking 1 tablet once a week, as originally scheduled on their chosen day. Patients should not take 2 tablets on the same day.

If one or both tablets of risedronate 75 mg on two consecutive days/month are missed, and the next month's scheduled doses are more than 7 days away, the patient should be instructed as follows: If both tablets are missed, take one risedronate 75 mg tablet in the morning after the day it is remembered and then the other tablet on the next consecutive morning; if only one risedronate 75 mg tablet is missed, take the missed tablet in the morning after the day it is remembered. Patients should then return to taking their risedronate 75 mg on two consecutive days/month as originally scheduled. Patients should not take more than two 75 mg tablets within 7 days. If one or both tablets of risedronate 75 mg on two consecutive days/month are missed, and the next month's scheduled doses are within 7 days, patients should wait until their next month's scheduled doses and then continue taking risedronate 75 mg on two consecutive days/month as originally scheduled.

If the dose of risedronate 150 mg once a month is missed, and the next month's scheduled dose is more than 7 days away, the patient should be instructed to take the missed tablet in the morning after the day it is remembered. Patients should then return to taking their risedronate 150 mg once a month as originally scheduled. Patients should not take more than one 150 mg tablet within 7 days. If the dose of risedronate 150 mg once a month is missed, and the next month's scheduled dose is within 7 days, patients should wait until their next month's scheduled dose and then continue taking risedronate 150 mg once a month as originally scheduled.

Usual Adult Dose for Prevention of Osteoporosis

For prevention or treatment of postmenopausal osteoporosis: 5 mg orally once daily or 35 mg orally once a week. Also, risedronate 75 mg may be given orally once a day on two consecutive days, for a total of two tablets monthly. Additionally, risedronate 150 mg may be given orally once a month.

For treatment of osteoporosis in men: 35 mg orally once a week.

For prevention or treatment of glucocorticoid induced osteoporosis: 5 mg orally once daily.

Patients should receive adequate supplements of calcium and vitamin D.

Patients should be instructed that if they miss a dose of risedronate 35 mg once a week, they should take 1 tablet on the morning after they remember and return to taking 1 tablet once a week, as originally scheduled on their chosen day. Patients should not take 2 tablets on the same day.

If one or both tablets of risedronate 75 mg on two consecutive days/month are missed, and the next month's scheduled doses are more than 7 days away, the patient should be instructed as follows: If both tablets are missed, take one risedronate 75 mg tablet in the morning after the day it is remembered and then the other tablet on the next consecutive morning; if only one risedronate 75 mg tablet is missed, take the missed tablet in the morning after the day it is remembered. Patients should then return to taking their risedronate 75 mg on two consecutive days/month as originally scheduled. Patients should not take more than two 75 mg tablets within 7 days. If one or both tablets of risedronate 75 mg on two consecutive days/month are missed, and the next month's scheduled doses are within 7 days, patients should wait until their next month's scheduled doses and then continue taking risedronate 75 mg on two consecutive days/month as originally scheduled.

If the dose of risedronate 150 mg once a month is missed, and the next month's scheduled dose is more than 7 days away, the patient should be instructed to take the missed tablet in the morning after the day it is remembered. Patients should then return to taking their risedronate 150 mg once a month as originally scheduled. Patients should not take more than one 150 mg tablet within 7 days. If the dose of risedronate 150 mg once a month is missed, and the next month's scheduled dose is within 7 days, patients should wait until their next month's scheduled dose and then continue taking risedronate 150 mg once a month as originally scheduled.

Renal Dose Adjustments

Residronte is not recommended for use in patients with severe renal impairment (creatinine clearance less than 30 mL/min) because of lack of clinical experience. No dosage adjustment is necessary in patients with a creatinine clearance of 30 or more mL/min.

Liver Dose Adjustments

Data not available

Precautions

Patients should remain upright for at least 30 minutes following administration of risedronate and until after their first food of the day. Safety and effectiveness have not been established in pediatric patients (less than 18 years of age).

Dialysis

Data not available

Other Comments

Risedronate should be administered with 6 to 8 ounces of plain water at least 30 minutes before the first food, beverage or medication of the day. Beverages other than water, food, and certain medications reduce the absorption of risedronate. Absorption may be improved by waiting more than 30 minutes before eating or drinking liquids other than water.

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