Medication Guide App

Optimark Dosage

Generic name: gadoversetamide
Dosage form: injection, solution

The information at Drugs.com is not a substitute for medical advice. ALWAYS consult your doctor or pharmacist.

Dosing Guidelines

  • Administer Optimark as a bolus peripheral intravenous injection at a dose of 0.2 mL/kg (0.1 mmol/kg) and at a rate of 1 to 2 mL/sec delivered by manual or by power injection (see Table 1).
  • Use sterile technique to withdraw and administer Optimark.
  • Follow injection with a 5 mL normal saline flush to ensure complete administration of the contrast.
  • Discard unused portions of the drug.

Table 1   Dosage Chart for Optimark Injection

Body Weight
Kilograms (kg)

0.1 mmol/kg
Volume (mL)

  40

  8

  50

10

  60

12

  70

14

  80

16

  90

18

100

20

110

22

120

24

130

26

140

28

150

30

Drug Handling

  • Visually inspect Optimark for particulate matter and discoloration prior to administration. Do not use the solution if it is discolored or particulate matter is present.
  • Do not mix Optimark with other medications or parenteral nutrition and do not administer Optimark in the same intravenous line as other medications because of the potential for chemical incompatibility.

Imaging

  • Complete the imaging procedure within 1 hour of the injection of Optimark.
  • Paramagnetic contrast agents may impair the visualization of lesions seen on non-contrast MRI. Interpret Optimark MR images with companion non-contrast MR images [see Clinical Pharmacology (12.2)].
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