Optimark Dosage

Generic name: GADOVERSETAMIDE 0.5mmol in 1mL
Dosage form: injection, solution
Drug class: Magnetic resonance imaging contrast media

Medically reviewed by Drugs.com. Last updated on Apr 22, 2024.

Administer Optimark as a bolus peripheral intravenous injection at a dose of 0.2 mL/kg (0.1 mmol/kg) and at a rate of 1 to 2 mL/sec delivered by manual or by power injection (see Table 1).
Use sterile technique to withdraw and administer Optimark.
Follow injection with a 5 mL normal saline flush to ensure complete administration of the contrast.
Discard unused portions of the drug.

Table 1 Dosage Chart for Optimark Injection
Body Weight Kilograms (kg)	0.1 mmol/kg Volume (mL)
40	8
50	10
60	12
70	14
80	16
90	18
100	20
110	22
120	24
130	26
140	28
150	30

Visually inspect Optimark for particulate matter and discoloration prior to administration. Do not use the solution if it is discolored or particulate matter is present.
Do not mix Optimark with other medications or parenteral nutrition and do not administer Optimark in the same intravenous line as other medications because of the potential for chemical incompatibility.

Complete the imaging procedure within 1 hour of the injection of Optimark.
Paramagnetic contrast agents may impair the visualization of lesions seen on non-contrast MRI. Interpret Optimark MR images with companion non-contrast MR images [see Clinical Pharmacology (12.2)].