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Nimodipine Dosage

This dosage information may not include all the information needed to use Nimodipine safely and effectively. See additional information for Nimodipine.

The information at Drugs.com is not a substitute for medical advice. ALWAYS consult your doctor or pharmacist.

Usual Adult Dose for:

Additional dosage information:

Usual Adult Dose for Subarachnoid Hemorrhage

60 mg orally every 4 hours
Therapy should be started within 96 hours of the event and continued for 21 days.

Usual Adult Dose for Ischemic Stroke

(Not approved by FDA)

30 mg orally every 6 hours
Therapy should be started within 24 hours of the event and continued for 28 days.

Usual Adult Dose for Migraine Prophylaxis

(Not approved by FDA)

30 mg orally every 6 hours

Renal Dose Adjustments

Data not available

Liver Dose Adjustments

Subarachnoid hemorrhage: 30 mg orally every 4 hours

Patients should be monitored closely for changes in blood pressure and/or heart rate.

Precautions

Nimodipine should not be administered IV or by other parenteral routes. Deaths and serious life threatening adverse events have been reported when the contents of nimodipine capsules were injected parenterally. Healthcare providers who prescribe, dispense, or administer nimodipine should be instructed to administer nimodipine capsules orally only. If nimodipine is inadvertently administered IV, clinically significant hypotension may require cardiovascular support with pressor agents. Specific treatments for calcium channel blocker overdose should also be given promptly.

Blood pressure should be monitored carefully during nimodipine therapy.

Safety and effectiveness have not been established in pediatric patients (less than 18 years of age).

Dialysis

Data not available

Since nimodipine is highly protein bound, removal by hemodialysis is unlikely.

Other Comments

For patients unable to swallow a capsule, oral administration may be achieved by using a syringe to extract the gel inside the capsule and administering the nimodipine gel through the patient's nasogastric tube or G-tube. The tube should then be rinsed with 30 mL of normal saline following administration.

Nimodipine should be given at least 1 hour before or 2 hours after meals.

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