Nimodipine Side Effects

Some side effects of nimodipine may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA.

For the Consumer

Applies to nimodipine: oral capsule

Get emergency medical help if you have any of these signs of an allergic reaction while taking nimodipine: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have:

• a light-headed feeling, like you might pass out;

• easy bruising or bleeding;

• fast or slow heart rate; or

• swelling in your ankles or feet.

Common side effects may include:

• nausea, diarrhea, upset stomach;

• headache; or

• mild rash.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects.

For Healthcare Professionals

Applies to nimodipine: oral capsule

Cardiovascular

Cardiovascular effects have frequently been associated with the use of nimodipine, and are related to its vasodilatory properties. Mild to moderate hypotension has been reported in up to 5% of patients, and was the reason less than 1% of patients chose to discontinue therapy. Bradycardia has been reported and may be severe in rare cases. Rare cardiovascular side effects have included tachycardia, hypertension, peripheral edema, dizziness, and flushing. A case of pulmonary vasoconstriction has been associated with the use of this drug.

Nervous system

The incidence of nervous system side effects associated with the use of nimodipine has been similar to placebo in large studies. Headache has been reported in 4% of patients, and is believed to be due to the vasodilatory properties of nimodipine.

Hepatic

Hepatic effects include transient, reversible elevations in liver function tests.

Hematologic

Hematologic side effects are rare and have included thrombocytopenia and anemia.

Gastrointestinal

Gastrointestinal intolerance occurs occasionally.

Dermatologic

Dermatologic effects include occasional cases of rash.

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