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Miglitol Dosage

Applies to the following strength(s): 25 mg ; 50 mg ; 100 mg

The information at is not a substitute for medical advice. ALWAYS consult your doctor or pharmacist.

Usual Adult Dose for:

Additional dosage information:

Usual Adult Dose for Diabetes Type 2

Initial dose: 25 mg orally 3 times a day at the beginning (with the first bite) of each meal.

Renal Dose Adjustments

If serum creatinine is greater than 2.0 mg/dL, miglitol is not recommended.

Liver Dose Adjustments

Data not available

Dose Adjustments

The dose may be increased after 4 to 8 weeks to 50 mg orally 3 times a day to maintain a desired blood glucose level. If this dosage does not provide an adequate response after 3 months, an increase to 100 mg orally 3 times a day may be used. If no further improvement is seen at this dosage, and miglitol therapy is to be continued, a reduction to 50 mg orally 3 times a day is recommended to reduce the likelihood of gastrointestinal adverse effects.


Since miglitol blunts the rise in blood glucose levels following ingestion of carbohydrates, simple sugars (dextrose, D glucose) are recommended to treat hypoglycemic episodes.


Data not available

Other Comments

The maximum recommended daily dose is 300 mg. Patients are strongly encouraged to comply with a stable diet and to be cognizant of the increased risk of hypoglycemia when insulin or sulfonylureas are coadministered.

Safety and effectiveness have not been established in pediatric patients (less than 18 years of age).