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Flurandrenolide Topical Dosage

Applies to the following strength(s): 0.05% ; 0.025% ; 4 mcg/cm2

The information at Drugs.com is not a substitute for medical advice. ALWAYS consult your doctor or pharmacist.

Usual Adult Dose for:

Usual Pediatric Dose for:

Additional dosage information:

Usual Adult Dose for Dermatitis

Cream, ointment, lotion: Apply a thin film topically to the affected area(s) 2 to 3 times a day
Tape: Apply every 12 to 24 hours or as directed to clean, dry skin that is free of hair

Comments:
-For the management of psoriasis or recalcitrant conditions, occlusive dressings may be used.
-Tape should be replaced every 12 to 24 hours to reduce adverse reactions.
-Tape should always be cut, never torn.

Uses: Relief of the inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses, particularly dry, scaling localized lesions

Usual Adult Dose for Eczema

Cream, ointment, lotion: Apply a thin film topically to the affected area(s) 2 to 3 times a day
Tape: Apply every 12 to 24 hours or as directed to clean, dry skin that is free of hair

Comments:
-For the management of psoriasis or recalcitrant conditions, occlusive dressings may be used.
-Tape should be replaced every 12 to 24 hours to reduce adverse reactions.
-Tape should always be cut, never torn.

Uses: Relief of the inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses, particularly dry, scaling localized lesions

Usual Adult Dose for Psoriasis

Cream, ointment, lotion: Apply a thin film topically to the affected area(s) 2 to 3 times a day
Tape: Apply every 12 to 24 hours or as directed to clean, dry skin that is free of hair

Comments:
-For the management of psoriasis or recalcitrant conditions, occlusive dressings may be used.
-Tape should be replaced every 12 to 24 hours to reduce adverse reactions.
-Tape should always be cut, never torn.

Uses: Relief of the inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses, particularly dry, scaling localized lesions

Usual Pediatric Dose for Dermatitis

Cream, ointment, lotion: Apply a thin film topically to the affected area(s) 2 to 3 times a day
Tape: Apply every 12 to 24 hours or as directed to clean, dry skin that is free of hair

Comments:
-For the management of psoriasis or recalcitrant conditions, occlusive dressings may be used.
-Tape should be replaced every 12 to 24 hours to reduce adverse reactions.
-Tape should always be cut, never torn.

Uses: Relief of the inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses, particularly dry, scaling localized lesions

Usual Pediatric Dose for Eczema

Cream, ointment, lotion: Apply a thin film topically to the affected area(s) 2 to 3 times a day
Tape: Apply every 12 to 24 hours or as directed to clean, dry skin that is free of hair

Comments:
-For the management of psoriasis or recalcitrant conditions, occlusive dressings may be used.
-Tape should be replaced every 12 to 24 hours to reduce adverse reactions.
-Tape should always be cut, never torn.

Uses: Relief of the inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses, particularly dry, scaling localized lesions

Usual Pediatric Dose for Psoriasis

Cream, ointment, lotion: Apply a thin film topically to the affected area(s) 2 to 3 times a day
Tape: Apply every 12 to 24 hours or as directed to clean, dry skin that is free of hair

Comments:
-For the management of psoriasis or recalcitrant conditions, occlusive dressings may be used.
-Tape should be replaced every 12 to 24 hours to reduce adverse reactions.
-Tape should always be cut, never torn.

Uses: Relief of the inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses, particularly dry, scaling localized lesions

Renal Dose Adjustments

Data not available

Liver Dose Adjustments

Data not available

Precautions

Pediatric: Children may absorb proportionally larger amounts after topical application and may be more prone to systemic effects. HPA axis suppression, intracranial hypertension, and Cushing's syndrome have been reported in children receiving topical corticosteroids. Prolonged use may affect growth velocity; growth should be routinely monitored in pediatric patients.

Consult WARNINGS section for additional precautions.

Dialysis

Data not available

Other Comments

Administration advice:
-Rub in gently and completely
-Administration of topical corticosteroids to pediatric patients should be limited to the least amount compatible with an effective therapeutic regimen. Chronic corticosteroid therapy may interfere with the growth and development of pediatric patients.
-If irritation develops, topical corticosteroids should be discontinued and appropriate therapy instituted.

Monitoring:
-Endocrine: HPA-axis suppression (Urinary free-cortisol test, ACTH-stimulation test)
-Patients receiving a large dose of a potent topical steroid applied to a large surface area or under an occlusive dressing should be evaluated periodically for evidence of HPA axis suppression.
-If used on the face, courses should be limited to five days and occlusion should not be used.
-In the presence of skin infections, the use of an appropriate antifungal or antibacterial agent should be instituted. If a favorable response does not occur, this drug should be discontinued until the infection has been adequately controlled.

Patient advice:
-This drug is to be used as directed by the physician. It is for external use only. Avoid contact with the eyes, face, underarms, or groin areas.
-If no improvement is seen within 2 weeks, patients should contact their healthcare provider.
-Patients should be advised not to use this medication for any disorder other than that for which it was prescribed.
-The treated skin area should not be bandaged or otherwise covered or wrapped unless directed to do so by the physician.
-Patients should report any signs of local adverse reactions, especially under occlusive dressings.
-Parents of pediatric patients should be advised not to use tight-fitting diapers or plastic pants on a patient being treated in the diaper area, because these garments may constitute occlusive dressings.
-Do not use other corticosteroid-containing products while using this drug without first consulting a physician.

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