Ethacrynic Acid Dosage
This dosage information may not include all the information needed to use Ethacrynic Acid safely and effectively. See additional information for Ethacrynic Acid.
The information at Drugs.com is not a substitute for medical advice. ALWAYS consult your doctor or pharmacist.
Usual Adult Dose for:
Additional dosage information:
Usual Adult Dose for Ascites
Oral: 50 mg once a day with food.
IV: 50 mg once.
Usual Adult Dose for Edema
Oral: 50 mg once a day with food.
IV: 50 mg once.
Usual Adult Dose for Nonobstructive Oliguria
Oral: 50 mg once a day with food.
IV: 50 mg once.
Usual Adult Dose for Pulmonary Edema
Oral: 50 mg once a day with food.
IV: 50 mg once.
Usual Adult Dose for Renal Failure
Oral: 50 mg once a day with food.
IV: 50 mg once.
Renal Dose Adjustments
CrCl < 50 mL/min: Oral: 25 mg once a day with food.
IV: 25 mg once.
Liver Dose Adjustments
Ethacrynic acid should be used with caution in patients with impaired hepatic function or progressive liver disease, since minor alterations of fluid and electrolyte balance may precipitate hepatic coma.
Dose Adjustments
Oral doses can be increased by 25 to 50 mg/day.
Most patients respond to 50 to 100 mg/day.
A second IV dose can be administered in 6 to 8 hours.
Precautions
Ethacrynic acid should be used with caution in patients with severe liver disease or renal dysfunction.
Dialysis
Ethacrynic acid is not removed by hemo- or peritoneal dialysis.
Other Comments
The maximum dose is 200 mg twice a day.
