Ethacrynic Acid Dosage

This dosage information may not include all the information needed to use Ethacrynic Acid safely and effectively. See additional information for Ethacrynic Acid.

The information at Drugs.com is not a substitute for medical advice. ALWAYS consult your doctor or pharmacist.

Usual Adult Dose for:

Additional dosage information:

Usual Adult Dose for Ascites

Oral: 50 mg once a day with food.
IV: 50 mg once.

Usual Adult Dose for Edema

Oral: 50 mg once a day with food.
IV: 50 mg once.

Usual Adult Dose for Nonobstructive Oliguria

Oral: 50 mg once a day with food.
IV: 50 mg once.

Usual Adult Dose for Pulmonary Edema

Oral: 50 mg once a day with food.
IV: 50 mg once.

Usual Adult Dose for Renal Failure

Oral: 50 mg once a day with food.
IV: 50 mg once.

Renal Dose Adjustments

CrCl < 50 mL/min: Oral: 25 mg once a day with food.
IV: 25 mg once.

Liver Dose Adjustments

Ethacrynic acid should be used with caution in patients with impaired hepatic function or progressive liver disease, since minor alterations of fluid and electrolyte balance may precipitate hepatic coma.

Dose Adjustments

Oral doses can be increased by 25 to 50 mg/day.
Most patients respond to 50 to 100 mg/day.
A second IV dose can be administered in 6 to 8 hours.

Precautions

Ethacrynic acid should be used with caution in patients with severe liver disease or renal dysfunction.

Dialysis

Ethacrynic acid is not removed by hemo- or peritoneal dialysis.

Other Comments

The maximum dose is 200 mg twice a day.

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