Eszopiclone Dosage

The information at Drugs.com is not a substitute for medical advice. ALWAYS consult your doctor or pharmacist.

Usual Adult Dose for:

Usual Geriatric Dose for:

Additional dosage information:

Usual Adult Dose for Insomnia

Initial dose: 1 mg orally immediately before bedtime
Maintenance dose: 1 to 3 mg orally immediately before bedtime
Maximum dose: 3 mg orally immediately before bedtime

Comments: Patients should be reevaluated if insomnia persists after 7 to 10 days of eszopiclone therapy.

Usual Geriatric Dose for Insomnia

Initial dose: 1 mg orally immediately before bedtime
Maximum dose: 2 mg orally immediately before bedtime

Comments: Patients should be reevaluated if insomnia persists after 7 to 10 days of eszopiclone therapy.

Renal Dose Adjustments

No dosage adjustment recommended

Liver Dose Adjustments

Mild to moderate liver dysfunction: No adjustment recommended
Severe liver dysfunction: Maximum dose is 2 mg orally immediately before bedtime

Dose Adjustments

Maximum dose in debilitated patients or in patients on concomitant CYP450 3A4 inhibitors: 2 mg orally immediately before bedtime

Precautions

Safety and effectiveness have not been established in patients younger than 18 years.

Consult WARNINGS section for additional precautions

US Controlled Substance: Schedule IV

Dialysis

Data not available

Other Comments

Administration advice:
-Doses should be administered immediately before bedtime.
-The effects of eszopiclone on sleep onset may be reduced if it is taken with or immediately after a high-fat/heavy meal.

General:
-Taking a sedative/hypnotic while still up and about may result in short-term memory impairment, hallucinations, impaired coordination, dizziness, and lightheadedness.
-The risk of next day impairment of driving and other activities that require full alertness is increased following use of 2 mg or 3 mg doses.
-Withdrawal effects may occur if the dose is rapidly reduced or treatment discontinued.

Patient advice:
-The morning after taking eszopiclone, your ability to drive safely and think clearly may be decreased; avoid driving or engaging in other hazardous activities or activities requiring complete mental alertness the day after use, if you are taking a dose of 3 mg before bedtime.

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