Eszopiclone Pregnancy and Breastfeeding Warnings

Eszopiclone is also known as: Lunesta

Eszopiclone Pregnancy Warnings

Animal studies have reported decreased fertility thought to be due to effects in both males and females. No females became pregnant when both males and females where treated with the highest doses. Other effects have been reported to include preimplantation loss, abnormal estrus cycles, decreases in sperm number and motility, and increases in morphologically abnormal sperm.

Eszopiclone has been assigned to pregnancy category C by the FDA. Animal studies have revealed evidence of slight reductions in fetal weight and evidence of developmental delay at maternally toxic doses. Increased postimplantation loss, decreased postnatal pup weights and survival, and increased pup startle response were reported to occur at all doses. Eszopiclone has no established use in labor and delivery. There are no controlled data in human pregnancy. Eszopiclone should only be given during pregnancy when benefits outweigh risks.

Eszopiclone Breastfeeding Warnings

There are no data on the excretion of eszopiclone into human milk. Because many drugs are excreted into human milk caution is recommended if eszopiclone is administered to a nursing woman.

See Also...

Disclaimer: Every effort has been made to ensure that the information provided by Cerner Multum, Wolters Kluwer Health and is accurate, up-to-date and complete, but no guarantee is made to that effect. In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource beyond the date hereof. This material does not endorse drugs, diagnose patients, or recommend therapy. This drug information is a reference resource designed as supplement to, and not a substitute for, the expertise, skill , knowledge, and judgement of healthcare practitioners in patient care. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Multum Information Services, Inc. does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. Copyright 2000-2008 Multum Information Services, Inc. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse, or pharmacist.