Esterified Estrogens Dosage

The information at Drugs.com is not a substitute for medical advice. ALWAYS consult your doctor or pharmacist.

Usual Adult Dose for:

Additional dosage information:

Usual Adult Dose for Osteoporosis

0.3 mg orally once a day.

In addition to hormonal therapy, adequate calcium intake is important for postmenopausal women who require treatment or prevention of osteoporosis. The average diet of older American women contains 400 to 600 mg of calcium per day. A suggested optimal intake is 1500 mg per day. If dietary intake is insufficient to achieve 1500 mg per day, supplementation may be useful in women who have no contraindication to calcium supplementation.

Long-term therapy (for more than 5 years) is generally necessary in order to obtain substantive benefits in reducing the risk of bone fracture. Maximal benefits are obtained if estrogen therapy is initiated as soon after menopause as possible. The optimal duration of therapy has not been definitively determined.

Usual Adult Dose for Postmenopausal Symptoms

1.25 mg orally once a day.

In general, the duration of hormone therapy for the treatment of postmenopausal symptoms should be limited. Treatment for one to five years is generally sufficient. However, long-term therapy (for the treatment/prophylaxis of osteoporosis and for risk reduction of cardiovascular disease) may be considered during the time in which the patient is being treated for postmenopausal symptoms.

Usual Adult Dose for Atrophic Urethritis

0.3 mg to 1.25 mg orally once a day.

In general, the duration of hormone therapy for the treatment of postmenopausal symptoms like atrophic vaginitis, kraurosis vulvae, or atrophic urethritis should be limited. Treatment for one to five years is generally sufficient.

Usual Adult Dose for Atrophic Vaginitis

0.3 mg to 1.25 mg orally once a day.

In general, the duration of hormone therapy for the treatment of postmenopausal symptoms like atrophic vaginitis, kraurosis vulvae, or atrophic urethritis should be limited. Treatment for one to five years is generally sufficient.

Usual Adult Dose for Hypoestrogenism

2.5 mg to 7.5 mg orally once a day in divided doses for 21 days followed by a 10 day rest period. This schedule is repeated as necessary to product bleeding.

Usual Adult Dose for Oophorectomy

1.25 mg orally once a day.

Usual Adult Dose for Primary Ovarian Failure

1.25 mg orally once a day.

Usual Adult Dose for Breast Cancer

10 mg orally three times a day for at least three months.

Estrogen therapy for breast cancer should be considered only for palliation in the treatment of metastatic disease in postmenopausal women and select male patients.

Usual Adult Dose for Prostate Cancer

1.25 mg to 2.5 mg orally three times a day.

Estrogen therapy for prostate cancer should be considered only for palliation in the treatment of metastatic disease in select patients.

Liver Dose Adjustments

Hepatic metabolism of estrogens may be impaired in patients with liver disease and caution is recommended.

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