Dronabinol Dosage

This dosage information may not include all the information needed to use Dronabinol safely and effectively. See additional information for Dronabinol.

The information at Drugs.com is not a substitute for medical advice. ALWAYS consult your doctor or pharmacist.

Usual Adult Dose for:

Usual Pediatric Dose for:

Additional dosage information:

Usual Adult Dose for Nausea/Vomiting - Chemotherapy Induced

Initial: 5 mg/m2, 1 to 3 hours prior to chemotherapy treatment, then every 2 to 4 hours after chemotherapy for a total of 4 to 6 doses per day.

Usual Adult Dose for Anorexia

Initial: 2.5 mg orally twice daily, before lunch and supper.

Maximum: 20 mg daily, given in 4 divided doses.

Usual Pediatric Dose for Nausea/Vomiting - Chemotherapy Induced

Initial: 5 mg/m2, 1 to 3 hours prior to chemotherapy treatment, then every 2 to 4 hours after chemotherapy for a total of 4 to 6 doses per day.

Renal Dose Adjustments

Data not available

Liver Dose Adjustments

Data not available

Dose Adjustments

If the initial antiemetic dose is not effective, and not significant side effects are reported, augment dose by increments of 2.5 mg/m2, to a maximum of 15 mg/m2 per dose.

Patients that receive dronabinol for appetite stimulation who can not tolerate the 5 mg/day dose, these patients may be able to take 2.5 mg once daily in the evening or at bedtime.

Precautions

Because of the potential for side effects such as hypotension, hypertension, syncope, or tachycardia, caution is recommended if dronabinol is to be used in patients with cardiac disorders.

Caution is also recommended if dronabinol is to be used in patients with a history of substance abuse including alcohol abuse or dependence.

Because dronabinol may exacerbate mania, depression, or schizophrenia, both caution and psychiatric monitoring are recommended if dronabinol is to be used in patients with a history of these illnesses.

Caution is recommended if dronabinol is to be used in the treatment of anorexia and weight loss in elderly patients with AIDS both because the elderly may be more sensitive to the psychoactive effects and because the use of dronabinol in this patient population has not been studied.

Dialysis

Data not available

Other Comments

Dronabinol may be administered without regard to meals.

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