Clariscan Dosage

Generic name: GADOTERATE MEGLUMINE 376.9mg in 1mL
Dosage form: injection, solution
Drug class: Magnetic resonance imaging contrast media

Medically reviewed by Drugs.com. Last updated on Jan 11, 2024.

Dosing Guidelines

For adult and pediatric patients (including term neonates), the recommended dose of Clariscan is 0.2 mL/kg (0.1 mmol/kg) body weight administered as an intravenous bolus injection, manually or by power injector, at a flow rate of approximately 2 mL/second for adults and 1-2 mL/second for pediatric patients. Table 1 provides weight-adjusted dose volumes.

Table 1: Volumes of Clariscan Injection by Body Weight
Body Weight		Volume
Pounds (lb)	Kilograms (kg)	Milliliters (mL)
5.5	2.5	0.5
11	5	1
22	10	2
44	20	4
66	30	6
88	40	8
110	50	10
132	60	12
154	70	14
176	80	16
198	90	18
220	100	20
242	110	22
264	120	24
286	130	26
308	140	28
330	150	30

To ensure complete injection of Clariscan, the injection may be followed by normal saline flush. Contrast MRI can begin immediately following Clariscan injection.

Drug Handling

Visually inspect Clariscan for particulate matter prior to administration. Do not use the solution if particulate matter is present or if the container appears damaged. Clariscan should be a clear, colorless to yellow solution.
Do not mix with other drugs or parenteral nutrition.
Discard any unused portions of the drug.

Directions for Use of Clariscan (gadoterate meglumine) Injection

Glass vial:

Aseptically draw up the contrast medium into a disposable syringe and use immediately.

Plastic pre-filled syringe:

Holding the syringe vertically so the tip cap is pointed upward, aseptically remove the tip cap from the tip of the syringe and attach either a sterile, disposable needle or compatible needleless luer lock tubing set using a push- twist action. At this point, the tubing set is not attached to a patient's intravenous connection.
- If using a needleless luer lock tubing set, check the connection between the syringe and the tubing as the fluid flows. Ensure that the connection is successful before administration of Clariscan Injection.
- If using a needle, hold the syringe vertically and push plunger forward until all of the air is evacuated and fluid either appears at the tip of the needle or the tubing is filled. Following the usual venous blood aspiration procedure, complete the Clariscan injection.
To ensure complete delivery of the contrast medium, the injection may be followed by a normal saline flush.
Properly dispose of the syringe and any other materials used.

Plastic pre-filled syringe