Brimonidine / Brinzolamide Ophthalmic Dosage

Medically reviewed by Drugs.com. Last updated on Aug 25, 2023.

Usual Adult Dose for Intraocular Hypertension

1 drop in the affected eye(s) 3 times per day

Comments:

• This drug may be used concomitantly with other topical ophthalmic drugs to lower intraocular pressure.
• If more than one topical ophthalmic drug is being used, the drugs should be administered at least 5 minutes apart.

Use: To lower elevated intraocular pressure (IOP) in patients with open-angle glaucoma or ocular hypertension.

Usual Adult Dose for Glaucoma (Open Angle)

1 drop in the affected eye(s) 3 times per day

Comments:

• This drug may be used concomitantly with other topical ophthalmic drugs to lower intraocular pressure.
• If more than one topical ophthalmic drug is being used, the drugs should be administered at least 5 minutes apart.

Use: To lower elevated intraocular pressure (IOP) in patients with open-angle glaucoma or ocular hypertension.

Usual Pediatric Dose for Intraocular Hypertension

2 years or older:
1 drop in the affected eye(s) 3 times per day

Comments:

• This drug may be used concomitantly with other topical ophthalmic drugs to lower intraocular pressure.
• If more than one topical ophthalmic drug is being used, the drugs should be administered at least 5 minutes apart.

Use: To lower elevated intraocular pressure (IOP) in patients with open-angle glaucoma or ocular hypertension.

Usual Pediatric Dose for Glaucoma (Open Angle)

2 years or older:
1 drop in the affected eye(s) 3 times per day

Comments:

• This drug may be used concomitantly with other topical ophthalmic drugs to lower intraocular pressure.
• If more than one topical ophthalmic drug is being used, the drugs should be administered at least 5 minutes apart.

Use: To lower elevated intraocular pressure (IOP) in patients with open-angle glaucoma or ocular hypertension.

Renal Dose Adjustments

Severe renal impairment (CrCl less than 30 mL/min): Not recommended

Liver Dose Adjustments

Severe hepatic impairment: Use with caution

Precautions

Safety and efficacy have not been established in patients younger than 2 years.

Consult WARNINGS section for additional precautions.

Dialysis

Data not available

Other Comments

Administration advice:

• This drug is for topical use only and it is not for injection or oral ingestion.
• Shake well before use.

Patient advice:

• Pressure should be applied to the tear duct immediately following administration of the drug.
• To avoid contamination of the solution, the container should be kept tightly closed.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer