Bismuth Subsalicylate Dosage

Usual Adult Dose for Dyspepsia

524 mg orally every 30 to 60 minutes as needed not to exceed 8 doses in any 24 hour period.
Alternatively, 1048 mg may be given orally every hour not to exceed 4 doses in any 24 hour period.

Usual Adult Dose for Helicobacter pylori Infection

524 mg orally 4 times a day.

Usual Pediatric Dose for Diarrhea

Non-specific diarrhea:

<3 years: use with caution

3 to 6 years: 87 mg every 30 minutes to 1 hour as needed.

6 to 9 years: 175 mg every 30 minutes to 1 hour as needed.

9 to 12 years: 262 mg every 30 minutes to 1 hour as needed.

Usual Pediatric Dose for Diarrhea - Chronic

Chronic Infantile Diarrhea:

2 to 24 months: 44 mg every 4 hours

24 to 48 months: 87 mg every 4 hours

48 to 70 months: 175 mg every 4 hours

Usual Pediatric Dose for Helicobacter pylori Infection

Dosage in children with Helicobacter Pylori Infection is not well established, the following doses have been used in conjunction with ampicillin and metronidazole.

<= 10 years: 262 mg four times a day for six weeks

> 10 years: 524 mg four times a day for six weeks

Renal Dose Adjustments

Data not available

Liver Dose Adjustments

Data not available

Precautions

Due to the risk with Reyes syndrome use with caution in children < 3 years and patients of all ages with or recovering from a viral illness, especially chicken pox and/or influenza.

Dialysis

Data not available

Other Comments

30 mL of the original liquid, 15 mL of the extra strength liquid, 2 chewable tablets, and 2 caplets all provide 524 mg. A triple drug regimen for H. pylori consisting of metronidazole, tetracycline, and bismuth subsalicylate has been used with a 90% eradication rate.

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