Bismuth subsalicylate Pregnancy and Breastfeeding Warnings
Bismuth subsalicylate is also known as: Bismarex, Bismatrol, Bismatrol Maximum Strength, Childrens Kaopectate, K-Pek, Kao-Tin Bismuth Subsalicylate Formula, Kaopectate, Kaopectate Anti-Diarrheal Upset Stomach Reliever, Kaopectate Extra Strength, Kapectolin (New Formula), Kola-Pectin DS, Maalox Total Relief, Maximum Strength Stress, Peptic Relief, Pepto-Bismol, Pepto-Bismol InstaCool, Pepto-Bismol Maximum Strength, Pepto-Bismol Original Strength, Percy Medicine, Pink Bismuth, Stomach Relief, Stress Maximum Strength
Bismuth subsalicylate Pregnancy Warnings
Bismuth subsalicylate has not been officially assigned to a pregnancy category. There are no reports of adverse fetal outcome associated with bismuth subsalicylate during pregnancy. Salicylate is absorbed during bismuth subsalicylate administration and may potentially result in fetal adverse effects, including premature closure of the ductus arteriosus when used late in pregnancy. Use of bismuth subsalicylate during the last half of pregnancy is not recommended.
Three pregnant patients who experienced bismuth encephalopathy from bismuth subnitrate delivered normal infants.
Bismuth subsalicylate Breastfeeding Warnings
Salicylate is absorbed during administration of bismuth subsalicylate. Due to the potential for adverse effects in the nursing infant, the American Academy of Pediatrics recommends salicylates be used with caution in nursing mothers.
References for pregnancy information
- Supino-Viterbo V, Sicard C, Risvegliato M, Rancurel G, Buge A "Toxic encephalopathy due to ingestion of bismuth salts: clinical and EEG studies of 45 patients." J Neurol Neurosurg Psychiatry 40 (1977): 748-52
- Briggs GG, Freeman RK, Yaffe SJ.. "Drugs in Pregnancy and Lactation. 5th ed." Baltimore, MD: Williams & Wilkins (1998):
References for breastfeeding information
- Committee on Drugs, 1992 to 1993 "The transfer of drugs and other chemicals into human milk." Pediatrics 93 (1994): 137-50
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