Skip to Content

Bismuth subsalicylate Pregnancy and Breastfeeding Warnings

Bismuth subsalicylate is also known as: Bismarex, Bismatrol, Bismatrol Maximum Strength, Childrens Kaopectate, K-Pek, Kao-Tin Bismuth Subsalicylate Formula, Kaopectate, Kaopectate Anti-Diarrheal Upset Stomach Reliever, Kaopectate Extra Strength, Kapectolin (New Formula), Kola-Pectin DS, Maalox Total Relief, Maximum Strength Stress, Peptic Relief, Pepto-Bismol, Pepto-Bismol InstaCool, Pepto-Bismol Maximum Strength, Pepto-Bismol Original Strength, Percy Medicine, Pink Bismuth, Stomach Relief, Stress Maximum Strength

Bismuth subsalicylate Pregnancy Warnings

Bismuth subsalicylate has not been officially assigned to a pregnancy category. There are no reports of adverse fetal outcome associated with bismuth subsalicylate during pregnancy. Salicylate is absorbed during bismuth subsalicylate administration and may potentially result in fetal adverse effects, including premature closure of the ductus arteriosus when used late in pregnancy. Use of bismuth subsalicylate during the last half of pregnancy is not recommended.

Three pregnant patients who experienced bismuth encephalopathy from bismuth subnitrate delivered normal infants.

See references

Bismuth subsalicylate Breastfeeding Warnings

Salicylate is absorbed during administration of bismuth subsalicylate. Due to the potential for adverse effects in the nursing infant, the American Academy of Pediatrics recommends salicylates be used with caution in nursing mothers.

See references

References for pregnancy information

  1. Supino-Viterbo V, Sicard C, Risvegliato M, Rancurel G, Buge A "Toxic encephalopathy due to ingestion of bismuth salts: clinical and EEG studies of 45 patients." J Neurol Neurosurg Psychiatry 40 (1977): 748-52
  2. Briggs GG, Freeman RK, Yaffe SJ.. "Drugs in Pregnancy and Lactation. 5th ed." Baltimore, MD: Williams & Wilkins (1998):

References for breastfeeding information

  1. Committee on Drugs, 1992 to 1993 "The transfer of drugs and other chemicals into human milk." Pediatrics 93 (1994): 137-50

See Also...

Disclaimer: Every effort has been made to ensure that the information provided by Cerner Multum, Wolters Kluwer Health and is accurate, up-to-date and complete, but no guarantee is made to that effect. In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource beyond the date hereof. This material does not endorse drugs, diagnose patients, or recommend therapy. This drug information is a reference resource designed as supplement to, and not a substitute for, the expertise, skill , knowledge, and judgement of healthcare practitioners in patient care. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Multum Information Services, Inc. does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. Copyright 2000-2008 Multum Information Services, Inc. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse, or pharmacist.