Asparaginase Erwinia Chrysanthemi Dosage

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Usual Adult Dose for:

Usual Pediatric Dose for:

Additional dosage information:

Usual Adult Dose for Acute Lymphoblastic Leukemia

To substitute for a dose of pegaspargase:
25,000 International Units/m2 intramuscularly three times a week (Monday/Wednesday/Friday) for six doses for each planned dose of pegaspargase

To substitute for a dose of native E. coli asparaginase:
25,000 International Units/m2 administered intramuscularly for each scheduled dose of native E. coli asparaginase within a treatment.

Usual Pediatric Dose for Acute Lymphoblastic Leukemia

To substitute for a dose of pegaspargase:
25,000 International Units/m2 intramuscularly three times a week (Monday/Wednesday/Friday) for six doses for each planned dose of pegaspargase

To substitute for a dose of native E. coli asparaginase:
25,000 International Units/m2 administered intramuscularly for each scheduled dose of native E. coli asparaginase within a treatment.

Renal Dose Adjustments

Data not available.

Liver Dose Adjustments

Data not available.

Precautions

The safety and efficacy of asparaginase Erwinia chrysanthemi has not been studied in geriatric patients.

Dialysis

Data not available.

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