Aphrodyne (yohimbine) Disease Interactions
There are 5 disease interactions with Aphrodyne (yohimbine):
Yohimbine (Includes Aphrodyne) ↔ Cardiovascular Disease
Severe Potential Hazard, High plausibility
Applies to: Hypertension, Heart Disease
Yohimbine can cause hypertension and tachycardia at recommended dosages. Large doses may cause hypotension and cardiac conduction disturbances. Therapy with yohimbine is generally not recommended in patients with hypertension, angina pectoris, or heart disease.
Yohimbine (Includes Aphrodyne) ↔ Peptic Ulcer Disease
Severe Potential Hazard, High plausibility
Applies to: Peptic Ulcer, History - Peptic Ulcer
Yohimbine may increase gastric acid secretion and gastrointestinal motility secondary to its cholinergic activity. Therapy with yohimbine is generally not recommended in patients with a history of peptic ulcer disease.
Yohimbine (Includes Aphrodyne) ↔ Renal Dysfunction
Severe Potential Hazard, High plausibility
Applies to: Renal Dysfunction
The use of yohimbine is contraindicated in patients with renal impairment. Yohimbine has mild antidiuretic effects, probably via stimulation of hypothalamic centers and release of posterior pituitary hormone. Agents that reduce or suppress diuresis may aggravate renal diseases.
Yohimbine (Includes Aphrodyne) ↔ Depression/Psychoses
Moderate Potential Hazard, Moderate plausibility
Applies to: Psychosis, Anxiety/Stress, Depression, History - Psychiatric Disorder
Yohimbine readily penetrates the blood-brain barrier and may cause anxiety, excitation, and other adverse nervous system effects. Precipitation or exacerbation of psychotic symptoms has been reported. Therapy with yohimbine should be administered cautiously in patients with anxiety, depression, or a history of psychiatric disorders.
Yohimbine (Includes Aphrodyne) ↔ Liver Disease
Moderate Potential Hazard, Moderate plausibility
Applies to: Liver Disease
Data are limited concerning the use of yohimbine in patients with liver disease. Yohimbine is thought to undergo metabolism in the liver. Therapy with yohimbine should be administered cautiously in patients with significantly impaired hepatic function.
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Aphrodyne (yohimbine) drug Interactions
There are 29 drug interactions with Aphrodyne (yohimbine)
Aphrodyne (yohimbine) alcohol/food Interactions
There is 1 alcohol/food interaction with Aphrodyne (yohimbine)
See also...
Drug Interaction Classification
The classifications below are a general guideline only. It is difficult to determine the relevance of a particular drug interaction to any individual given the large number of variables.
| Major | Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. |
| Moderate | Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. |
| Minor | Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. |
Do not stop taking any medications without consulting your healthcare provider.
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