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Valrubicin Disease Interactions

There are 2 disease interactions with valrubicin.

Major

Valrubicin (applies to valrubicin) perforated bladder

Major Potential Hazard, Moderate plausibility. Applicable conditions: Rupture of Bladder

Valrubicin is contraindicated in patients with perforated bladder or compromised bladder mucosa, including small bladder capacity that is unable to tolerate a 75 mL instillation. Evaluate the bladder before the intravesical instillation for severe irritable bladder symptoms, and in case of bladder perforation, delay the administration until bladder integrity has been restored. If this agent is administered to patients with bladder rupture or if perforation is suspected, significant systemic exposure may occur following intravesical administration and myelosuppression is possible. Weekly monitoring of complete blood counts should be performed for 3 weeks.

References

  1. "Product Information. Valstar (valrubicin)." Medeva Pharmaceuticals PROD (2001):
Major

Valrubicin (applies to valrubicin) urinary infection

Major Potential Hazard, Moderate plausibility. Applicable conditions: Urinary Tract Infection

Valrubicin is contraindicated in patients with current urinary tract infection.

References

  1. "Product Information. Valstar (valrubicin)." Medeva Pharmaceuticals PROD (2001):

Valrubicin drug interactions

There are 6 drug interactions with valrubicin.

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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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