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Ublituximab Disease Interactions

There are 3 disease interactions with ublituximab.

Major

Ublituximab (applies to ublituximab) hepatitis

Major Potential Hazard, Moderate plausibility. Applicable conditions: Infectious Hepatitis

The use of ublituximab is contraindicated in patients with active hepatitis B virus infection.

References

  1. (2022) "Product Information. Briumvi (ublituximab)." TG Therapeutics, Inc.
Moderate

Ublituximab (applies to ublituximab) infections

Moderate Potential Hazard, Moderate plausibility. Applicable conditions: Infection - Bacterial/Fungal/Protozoal/Viral

Serious, including life-threatening and fatal infections, have occurred in patients using ublituximab. Delay treatment in patients with an active infection until the infection is resolved. Vaccination with live-attenuated or
live vaccines is not recommended during treatment with ublituximab and after discontinuation, until B-cell repletion.

References

  1. (2022) "Product Information. Briumvi (ublituximab)." TG Therapeutics, Inc.
Moderate

Ublituximab (applies to ublituximab) renal/hepatic

Moderate Potential Hazard, Moderate plausibility. Applicable conditions: Renal Dysfunction, Liver Disease

The effect of moderate to severe renal impairment or moderate to severe hepatic impairment on the pharmacokinetics of ublituximab is unknown.

References

  1. (2022) "Product Information. Briumvi (ublituximab)." TG Therapeutics, Inc.

Ublituximab drug interactions

There are 402 drug interactions with ublituximab.

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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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