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Satralizumab Disease Interactions

There are 3 disease interactions with satralizumab.

Major

Satralizumab (applies to satralizumab) active hepatitis B

Major Potential Hazard, Moderate plausibility. Applicable conditions: Infectious Hepatitis

Satralizumab is contraindicated in patients with active hepatitis B infection. All patients should be screened for hepatitis B before treatment initiation.

References

  1. (2020) "Product Information. Enspryng (satralizumab)." Genentech
Major

Satralizumab (applies to satralizumab) tuberculosis

Major Potential Hazard, Moderate plausibility. Applicable conditions: Tuberculosis -- Active, Tuberculosis -- Latent

Satralizumab is contraindicated in patients with active or untreated latent tuberculosis. All patients should be screened for tuberculosis before treatment initiation and monitored for the development of symptoms or signs of tuberculosis during treatment, even if the initial testing is negative.

References

  1. (2020) "Product Information. Enspryng (satralizumab)." Genentech
Moderate

Satralizumab (applies to satralizumab) infections

Moderate Potential Hazard, Moderate plausibility. Applicable conditions: Infection - Bacterial/Fungal/Protozoal/Viral

Treatment with satralizumab can increase the risk of serious infections. Treatment should be delayed until any active infection is treated and resolved.

References

  1. (2020) "Product Information. Enspryng (satralizumab)." Genentech

Satralizumab drug interactions

There are 268 drug interactions with satralizumab.

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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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