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Dibenzyline Disease Interactions

There are 3 disease interactions with Dibenzyline (phenoxybenzamine).

Major

Phenoxybenzamine (applies to Dibenzyline) cardiovascular dysfunction

Major Potential Hazard, High plausibility. Applicable conditions: Cerebral Vascular Disorder, Ischemic Heart Disease, Congestive Heart Failure

The use of phenoxybenzamine is contraindicated when a decrease in blood pressure may be undesirable, such as in patients with marked cerebrovascular or coronary insufficiency in whom ischemia may be aggravated. Also, phenoxybenzamine- induced reflex tachycardia can precipitate frank congestive heart failure (CHF) and angina in patients with compensated CHF or coronary artery disease. Phenoxybenzamine should be used with caution under such circumstances.

References

  1. "Product Information. Dibenzyline (phenoxybenzamine)." SmithKline Beecham
Moderate

Phenoxybenzamine (applies to Dibenzyline) renal damage

Moderate Potential Hazard, Moderate plausibility. Applicable conditions: Renal Dysfunction

Phenoxybenzamine should be administered with caution in patients with marked renal damage.

References

  1. "Product Information. Dibenzyline (phenoxybenzamine)." SmithKline Beecham
Moderate

Phenoxybenzamine (applies to Dibenzyline) respiratory infections

Moderate Potential Hazard, Moderate plausibility. Applicable conditions: Pleuropulmonary Infection

The adrenergic blocking effect of phenoxybenzamine may aggravate the symptoms of respiratory infections. Caution is recommended when treating patients with respiratory infections.

References

  1. "Product Information. Dibenzyline (phenoxybenzamine)." SmithKline Beecham

Dibenzyline drug interactions

There are 196 drug interactions with Dibenzyline (phenoxybenzamine).

Dibenzyline alcohol/food interactions

There is 1 alcohol/food interaction with Dibenzyline (phenoxybenzamine).

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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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