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Empaveli Disease Interactions

There is 1 disease interaction with Empaveli (pegcetacoplan).

Major

Pegcetacoplan (applies to Empaveli) infections

Major Potential Hazard, Moderate plausibility. Applicable conditions: Infection - Bacterial/Fungal/Protozoal/Viral, Vaccination

Pegcetacoplan may predispose patients to serious, life-threatening, or fatal infections caused by encapsulated bacteria including Streptococcus pneumoniae, Neisseria meningitidis types A, C, W, Y, and B, and Haemophilus influenzae type B (Hib). Consider discontinuation of treatment in patients who are undergoing treatment for serious infections. It is recommended to vaccinate all patients against these bacteria according to the most current ACIP recommendations for patients with altered immunocompetence associated with complement deficiencies. Administer required vaccines at least 2 weeks prior to receiving the first dose to patients without a known history of vaccination. If immediate therapy is indicated, consider administering the required vaccine as soon as possible and provide patients with 2 weeks of antibacterial drug prophylaxis.

References

  1. (2021) "Product Information. Empaveli (pegcetacoplan)." Apellis Pharmaceuticals, Inc.

Empaveli drug interactions

There are 59 drug interactions with Empaveli (pegcetacoplan).

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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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