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Isatuximab Disease Interactions

There is 1 disease interaction with isatuximab.

Moderate

Isatuximab (applies to isatuximab) hepatic impairment

Moderate Potential Hazard, Moderate plausibility. Applicable conditions: Liver Disease

The effect of moderate (total bilirubin >1.5 times to 3 times ULN and any AST) and severe (total bilirubin >3 times ULN and any AST) hepatic impairment on isatuximab pharmacokinetics is unknown. Although no specific dose adjustments are recommended in this patient population, caution and monitoring is advised.

References

  1. (2020) "Product Information. Sarclisa (isatuximab)." sanofi-aventis

Isatuximab drug interactions

There are 230 drug interactions with isatuximab.

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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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