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Elrexfio Disease Interactions

There are 3 disease interactions with Elrexfio (elranatamab).

Moderate

Elranatamab (applies to Elrexfio) active infection

Moderate Potential Hazard, Moderate plausibility. Applicable conditions: Infection - Bacterial/Fungal/Protozoal/Viral

Elranatamab can cause serious and fatal infections. Patients should be evaluated for active infection before and during treatment with elranatamab, and administration should be avoided if infection is detected.

References

  1. (2023) "Product Information. Elrexfio (elranatamab)." Pfizer U.S. Pharmaceuticals Group
Moderate

Elranatamab (applies to Elrexfio) hepatic impairment

Moderate Potential Hazard, Moderate plausibility. Applicable conditions: Liver Disease

Elranatamab can cause increased levels of liver enzymes and bilirubin. The effect of moderate to severe hepatic impairment (total bilirubin >1.5 times ULN and any AST) on the pharmacokinetics of elranatamab has not been evaluated.

References

  1. (2023) "Product Information. Elrexfio (elranatamab)." Pfizer U.S. Pharmaceuticals Group
Moderate

Elranatamab (applies to Elrexfio) renal impairment

Moderate Potential Hazard, Moderate plausibility. Applicable conditions: Renal Dysfunction

Use elranatamab with caution in patients with severe renal impairment and end-stage renal disease as its effects on its pharmacokinetics have not been studied.

References

  1. (2023) "Product Information. Elrexfio (elranatamab)." Pfizer U.S. Pharmaceuticals Group

Elrexfio drug interactions

There are 381 drug interactions with Elrexfio (elranatamab).

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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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