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Anti-thymocyte globulin (rabbit) Disease Interactions

There are 2 disease interactions with anti-thymocyte globulin (rabbit).

Major

Anti-thymocyte globulin [rabbit] (applies to anti-thymocyte globulin (rabbit)) infections

Major Potential Hazard, Moderate plausibility. Applicable conditions: Infection - Bacterial/Fungal/Protozoal/Viral, Immunodeficiency, Bone Marrow Depression/Low Blood Counts

The use of anti-thymocyte globulin [rabbit] is contraindicated in patients who have active acute or chronic infections that contraindicate any additional immunosuppression. To prevent over-immunosuppression, physicians may wish to decrease the dose of the maintenance immunosuppression regimen during the period of therapy use. Low counts of platelets and white blood cells (including low counts of lymphocytes and neutrophils) have been identified and are reversible following dose adjustments. It is recommended to monitor patients carefully and administer appropriate anti-infective treatment when indicated. Also, total white blood cell and platelet counts should be monitored.

References

  1. "Product Information. Thymoglobulin (rabbit) (anti-thymocyte globulin (rabbit))." Genzyme Corporation
Major

Anti-thymocyte globulin [rabbit] (applies to anti-thymocyte globulin (rabbit)) vaccination

Major Potential Hazard, Moderate plausibility.

Patients recently treated with anti-thymocyte globulin [rabbit] should not receive immunizations with live viral vaccines.

References

  1. "Product Information. Thymoglobulin (rabbit) (anti-thymocyte globulin (rabbit))." Genzyme Corporation

Anti-thymocyte globulin (rabbit) drug interactions

There are 155 drug interactions with anti-thymocyte globulin (rabbit).

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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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