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Eylea Disease Interactions

There is 1 disease interaction with Eylea (aflibercept ophthalmic).

Major

Intravitreal injections (applies to Eylea) ocular infections

Major Potential Hazard, High plausibility. Applicable conditions: Uveitis, Orbital Infection, Infectious Endophthalmitis, Infectious Optic Neuritis

Drugs requiring intravitreal administration (including aflibercept, faricimab, pegaptanib, and ranibizumab) are contraindicated in patients with active intraocular inflammation or ocular/periocular infections; intravitreal injections have been associated with endophthalmitis. Patients should be advised to seek immediate medical attention from an ophthalmologist if the eye becomes red, photosensitive, or painful, or if a change in vision occurs in the days following drug administration.

References

  1. (2004) "Product Information. Macugen (pegaptanib ophthalmic)." OSI Pharmaceuticals Inc
  2. (2006) "Product Information. Lucentis (ranibizumab ophthalmic)." Genentech
  3. (2011) "Product Information. Eylea (aflibercept ophthalmic)." Regeneron Pharmaceuticals Inc
  4. (2022) "Product Information. Vabysmo (faricimab ophthalmic)." Genentech
View all 4 references

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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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