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Zepbound User Reviews & Ratings (Page 2)

Zepbound has an average rating of 9.1 out of 10 from a total of 47 reviews on Drugs.com. 89% of reviewers reported a positive experience, while 0% reported a negative experience.

Reviews for Zepbound

  • Anonymous
  • Taken for 1 to 6 months
  • February 26, 2024

For Weight Loss (Obesity/Overweight) "So far, so good. Rarely get hungry and can't eat too much. Side effects: Heartburn, reflux, constipation, hair loss. I will have to weigh myself in the morning, but I am guessing I am down about 8 lbs. in 5 weeks. Just started on the 5 ml. No exercise yet. Wine and alcohol will definitely slow down the progress. Not a lot of cravings for junk. Every now and then I want something fried, but it will have you on the crapper by the next morning! Stay away from greasy food on this! And YES, the needle DOES hurt to me!"

8 / 10
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22 Report
  • Mike
  • Taken for 1 to 6 months
  • March 5, 2024

For Weight Loss (Obesity/Overweight) "Been on Zepbound 7 weeks now. Lost about 22 lbs so far with no exercise. This stuff is amazing at curbing your appetite. But beware, stick to healthy foods and minimal portions because the nausea is otherworldly. I ate too much too late in the day yesterday. I had to leave work early today for the second time since being on this med. Light-headed, profuse sweating, chills, diarrhea almost non-stop and even puking. This med is a miracle, but you cannot mess around. Take it seriously. Cut back portions, minimal dairy, low sugar and don't eat too late. I'm excited to see how far I can go on this med. So thankful I have access."

10 / 10
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20 Report
  • Illin...
  • Taken for 1 to 6 months
  • February 14, 2024

For Weight Loss (Obesity/Overweight) "I have been on Zepbound for 6 weeks. (4 weeks 2.5) (2 weeks at 5.0) I have lost 23 lbs. 307-284 I ride bike/treadmill and lift weights. I eat 2300 calories a day. If I happen to eat too much, I don't seem to notice. But what I do notice is I don't crave food like before. Before, I used to still be hungry after dinner. Not anymore. That part of my brain that was ravenous for more is gone."

10 / 10
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22 Report

Frequently asked questions

  • Susan
  • Taken for 1 to 6 months
  • March 26, 2024

For Weight Loss (Obesity/Overweight) "I've been on Zepbound for about 3 months. I'm 5'3' and started at 167. So far I have lost 12 lbs. trying to maintain a 1,200 calorie diet. The main thing is to watch what you eat and quit when you are full. The only side effects I've seen are fatigue and constipation. The shots don't bother me at all and no nausea, thank goodness. The only thing I'm really worried about is gaining it back when I stop. Good luck to all!"

10 / 10
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14 Report
  • Tz018v
  • Taken for 1 to 6 months
  • April 12, 2024

For Weight Loss (Obesity/Overweight) "I am 64, 5’2” tall and weighed 210 when I started Zepbound with 2.5 mg on January 15, 2024. I had no side effects with 2.5 and lost 12 pounds the first month. I went up to 5.0 ml and still no side effects but lost only 5 pounds that month. Went up to 7.5 and started having mild nausea, diarrhea, and indigestion. Lost another 10 pounds that month. I'm on week 2 of 10 ml. Side effects are much worse. I've lost a total of 35 pounds but in week two my stomach physically hurts, nausea is much worse and so is diarrhea. I think I will not be able to complete the next two doses on 10 ml so looking to drop down to 5.0 for maintenance and hopefully continued weight loss."

8 / 10
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10 Report

Are you taking this medicine?

  • Tpott
  • Taken for 1 to 6 months
  • March 3, 2024

For Weight Loss (Obesity/Overweight) "50-year-old female with 100 lbs to lose and PCOS. Been on Zepbound for 6 weeks (just took 7th shot). Minimal side effects. Occasional nausea, headaches, and sore muscles, usually the day after injection, but they go away by the next day. Taking the 5 mg dose right now. I have been getting large injection site rashes with itching, burning, and swelling with the last 3 doses. The swelling and itching go down after 3-4 days, but the red spots are still visible from all 3 of the previous doses. I didn't get this with the 2.5mg dose at all. Hoping it was just this last box of the medicine and the next will be better. I have only lost 5 lbs in the 6 weeks I have been on it, which has been very disappointing. It has lowered my blood pressure though. It was on the high side of normal before, now it's perfect. Really hoping that going up to the 7.5mg dose will start having better results for me as I have got a long way to go, and hopefully the skin reactions won't get worse."

7 / 10
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18 Report
  • sherri
  • Taken for 1 to 6 months
  • March 18, 2024

For Weight Loss (Obesity/Overweight) "I have been on Zepbound for two months and have lost only 9 pounds. I don't eat breakfast because I am not hungry; this has been a lifelong habit of mine. I am hungry at noon and eat more than I should. I have found that I am eating too fast, which is causing me to not have the weight loss that I would have if I ate slower. I have noticed that when I eat slower, I stop eating when I am halfway done with my meal. Hopefully, I can break a lifelong habit of eating fast. I have no side effects from the drug or overeating."

4 / 10
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14 Report

More FAQ

  • disap...
  • Taken for 1 to 6 months
  • April 1, 2024

For Weight Loss (Obesity/Overweight) "After so many people I knew were doing so well on these injections, I started Zepbound 6 weeks ago. I was fine for 24 hours, then the side effects kicked in. I don't recall ever feeling this sick. Sulfur burps, churning stomach, started vomiting and diarrhea for 3 full days. I was sick for days after the first shot. I had no hunger while so very sick. Week 2 and 3 had no problems and the food cravings were gone. I was prepared to be very successful on this medication. Week 4 sulfur burps came back again, 24 hours after my injection. The same reactions returned but less violent; I was sick for 24 hours. Maybe a fluke? Week 5 and 24 hours in, same sulfur burps started it again: diarrhea, stomach spasms, and vomiting. Nope, off the Zepbound. I would rather stay fat than make myself sick with every dose. I never got beyond 2.5. I know this has been wonderful for some people; it's just not for me."

8 / 10
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  • Anonymous
  • Taken for less than 1 month
  • March 24, 2024

For Weight Loss (Obesity/Overweight) "Ten days on Zepbound. Love this medication. The energy it gives you is amazing. 1st day injection in thigh developed bruise and slight nausea and headache. But no biggie. 2nd shot belly super easy. Takes away urge to eat. No more stomach grumbling when hungry either. I have a protein shake in the morning, mid-morning protein bar, little bites throughout the morning. Small lunch and salmon or chicken for dinner. Veggies and fruit are important. No issue with bathroom. I take a fiber gummy and multivitamin daily. Treadmill and gym. After showering, I've been using lots of lotion on skin, massaging in. You'll be fine. Smart choices in foods. Yogurt gave me nausea as did tuna with mayonnaise. 6 lbs so far."

10 / 10
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  • baechr
  • Taken for 1 to 6 months
  • March 18, 2024

For Weight Loss (Obesity/Overweight) "Absolutely life-changing. For the first time in my life, I'm satisfied by reasonable portions. I'm not always thinking about the next thing that I'll be eating. I'm able to feel and respond to my actual hunger cues without my scarcity brain taking over. Even if I wasn't losing weight, the relief of food obsession and binge eating disorder would be worth it. Four weeks in, down 13 lbs and very satisfied. Only side effect has been feeling cold and some mild constipation."

10 / 10
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  • Dawn
  • Taken for less than 1 month
  • March 18, 2024

For Weight Loss (Obesity/Overweight) "Started Zepbound 2.5 mg just 3 days ago. For the first time in my LIFE, I am eating to nourish my body, and not to satisfy hunger or cravings! Super excited to see how the weight will drop with new habits. Downside, I wasted a pen the very first time I injected because I didn't remove the grey closure. My fault for not thoroughly following the instructions but total bummer because the cost of this med is not cheap and the pharmacy says they can't fill an Rx for just one pen. It would be nice if the manufacturer of the drug would allow a single pen to be purchased for a lesser cost."

8 / 10
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  • Revie...
  • Taken for 1 to 6 months
  • April 6, 2024

For Weight Loss (Obesity/Overweight) "I have been taking Zepbound for about 3 months now and have lost 18 lbs. The experience has been mostly unpleasant. The gastric issues that accompany the medication are almost unbearable. The desire to eat did not go away, and I mostly did not eat because I was always so nauseated and experiencing acid reflux. Every day has been miserable. It did make you feel good but not in a satisfied way, just full like you ate way too much to the point of feeling sick. It feels great to have lost 18 lbs, but I will probably not continue the shots due to the gastric issues."

6 / 10
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  • Saman...
  • Taken for less than 1 month
  • April 11, 2024

For Weight Loss (Obesity/Overweight) "5'4 female. Was 254, but lost weight by working out and came down to 234, which was not good enough. Started Zepbound 2.5 which was extremely hard for me to find. Had to wait months before I found a pharmacy that had it. I just took my second shot. No side effects (so far, knock on wood). I did weigh myself 2 days after I started taking it and lost 5lbs so now 229lb. But I think it's from working out, not Zepbound. I work out almost 7 days a week, maybe take 1 day off. I do 2-2.5 miles on weekdays & 3-4 on weekends. So I am hoping to lose more weight faster. But so far so good. I read so many reviews! I am just praying that getting my 5ml in 2 weeks won't be an issue. The needle is not painful and it is super easy to use! The spot I place the shot in is a little tender afterwards with a slight amount of blood after injection. I will weigh myself again maybe tomorrow after a week of taking it! I have zero desire to eat and don't eat much, so I have smaller meals."

9 / 10
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  • Jules
  • Taken for 1 to 6 months
  • April 23, 2024

For Weight Loss (Obesity/Overweight) "Six years ago (at age 45) I was diagnosed with peri-menopause and insulin resistance. I put on about 30 lbs and seemed powerless to stop it or lose it! I’m 5’10 so can carry more weight better than most, but still my BMI was high and I just felt unwell. My GYN had me try several things like Ozempic, Metformin and hormone patches. The hormone patches helped tremendously with peri-menopause symptoms, but the weight was still there. Thank God for Zepbound!! My PCP started me on it and I was cautiously optimistic. In 8 weeks I lost 10 lbs. First month (2.5 mg) I lost 3 lbs. My PCP said sometimes it takes your body time to catch on so be patient, and we started me on 5 mg. End of the second month I lost another 7 lbs! That is huge for me! Best part…I no longer think about sugar and sweets. I didn’t realize how addicted to sugar I was! Food noise is gone. Con: stomach side effects started at 5 mg and continue; hypoglycemia."

9 / 10
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  • mjeff...
  • Taken for 1 to 6 months
  • May 9, 2024

For Weight Loss (Obesity/Overweight) "I originally started the Zepbound shot at the end of this past January. I weighed a total of 202 lbs when I started it. That would be about 3-4 months ago. I was very self-conscious, I didn't want to take any pictures of myself, I felt disgusted by myself, I always brought myself down, etc. But now, now I weigh 154 lbs. I'm at the 10 mg of the Zepbound. I started off as the lowest and I'm still not at the highest, to be honest. I lost about 50 pounds in the last 4 months! I researched it and it'll take 16 months to lose about 50 pounds for a normal person who doesn't take anything. And I did it in 4 months with that shot! I never thought I would get to this weight, to be honest. In the beginning, I was going to the YMCA to work out every week to put in the extra work, etc. At first, I started losing like a pound a day, not even kidding, sometimes 2 lbs a day. Then it went to a pound every couple days, and it would vary."

10 / 10
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  • My...
  • Taken for 1 to 6 months
  • April 22, 2024

For Weight Loss (Obesity/Overweight) "Since starting Zepbound 13 weeks ago to shed 60 pounds, I've gradually increased from 2.5 mg to 10 mg. It's effective, but sleepless nights have become my unwelcome companions, especially on the higher doses. Heartburn and that uncomfortable chest sensation are no picnic either. Despite dropping 30 pounds, I feel drained—fatigue, dizziness, and concentration issues plague me. To tackle these side effects, I'll either stick to 10 mg or drop to 7.5 mg. But with a $1,000 monthly price tag and the hassle of hunting down my prescription, quitting Zepbound crosses my mind. Yet, the thought of returning to the weight loss battle isn't enticing either. Swapping out heavy meals for light options like chicken and soups helps ease discomfort, but what I really crave is a solid night's sleep. I'm giving it one last shot, tweaking my diet and powering through my remaining doses before deciding—is it worth it?"

6 / 10
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  • Paulie
  • April 23, 2024

For Weight Loss (Obesity/Overweight) "I am a 72-year-old female, 5'7", and 204 lbs. I started Zepbound 3 weeks ago. I don't have the nausea, diarrhea, and other ailments that I've read about, but I've had a problem with itching. From the top of my thighs, up my back and my front and my arms all itch a lot. My doctor told me to quit the injections for 3 weeks to see if it helped. For the first time, I didn't do what he recommended because at this point, I've lost 7 lbs and I'm very happy about that. Hopefully the itching will die down with time. I'm very optimistic about my success and I will continue. It's only costing me $245 a month which is very doable. Taking Benadryl and using cortisone cream seems to help."

10 / 10
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  • Marsha
  • Taken for less than 1 month
  • February 12, 2024

For Weight Loss (Obesity/Overweight) "I love it so far. I took Wegovy, which made me nauseous. No side effects with Zepbound. I only pay $15/month with my insurance (Cigna)."

9 / 10
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30 Report
  • Sandra
  • Taken for 1 to 6 months
  • May 2, 2024

For Weight Loss (Obesity/Overweight) "I am African American, age 54, weight 225 lbs. I started Zepbound a month ago after previously trying to lose weight with Wegovy in 2023 but ran into demand issues with Wegovy. Wegovy also gave me extreme nausea and vomiting but amazing weight loss results. Zepbound's needles leave bruises, and I get tension headaches on the 1st and 2nd day after injection. I also feel tired on the 2nd and 3rd day, but I am not as hungry. I do notice that when I eat poorly, I have explosive BMs, and when I eat clean, I feel constipated. I do notice the weight loss on the 2.5 mg dose but can't move into 5.0 due to shortages, and I am hoping it's not like my experience with Wegovy, and I'll have to stop the progress due to the shortage of dosages."

9 / 10
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  • smitty
  • Taken for 1 to 6 months
  • March 10, 2024

For Weight Loss (Obesity/Overweight) "I've been taking Zepbound for 4 weeks. I have had zero side effects and lost 9 pounds so far. I start the next dose in 3 days. I'll keep you posted, so far, so good!"

10 / 10
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  • Susan...
  • Taken for 1 to 6 months
  • April 7, 2024

For Weight Loss (Obesity/Overweight) "Nausea and constipation. I started on 2/22/2024 at 207 pounds, and now on 4/7/2024, I weigh 180 pounds."

8 / 10
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10 Report
  • Musta...
  • Taken for 1 to 6 months
  • March 22, 2024

"Going into week five and I feel just fine. I am down 10 pounds. No side effects. No issues. Don’t listen to everyone. It helped my A1c and even lower my cholesterol numbers."

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7 Report
  • Jesso
  • Taken for 1 to 6 months
  • April 1, 2024

For Weight Loss (Obesity/Overweight) "This medication has saved my life. Not only physically, but losing weight has helped my mental health as well. I had tried EVERYTHING before. I only hope that more insurances will begin covering it."

10 / 10
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6 Report

Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.