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Semaglutide for Cardiovascular Risk Reduction User Reviews

Brand names: Ozempic, Wegovy, Rybelsus

Semaglutide has an average rating of 6.4 out of 10 from a total of 190 reviews for the treatment of Cardiovascular Risk Reduction. 55% of reviewers reported a positive experience, while 32% reported a negative experience.

Semaglutide rating summary

6.4/10 average rating

190 ratings from 206 user reviews.

Compare all 36 medications used in the treatment of Cardiovascular Risk Reduction.

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Reviews for Semaglutide

  • Susie...
  • Taken for 6 months to 1 year
  • July 14, 2021

Ozempic (semaglutide) "I have been on ozempic for exactly 1 year as my insulin intake (injection) was far too high as well as Metformin. I was asked if I wanted to try ozempic and was told that it may help with weight loss too. In the course of the year I have lost over 9 stone in weight and gone from a ladies size 26 in clothing to a size 14 to 16. I have never been happier with my weight, my blood sugars are normal levels now which they were previously out of control."

10 / 10
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612 Report
  • Mary
  • March 6, 2021

Ozempic (semaglutide) "I was prescribed it for prediabetes and weight loss. Today in one week since my first injection and I lost 6 lbs....in one week, last diet (one of very many) it took me 3 month to lose 10 lb by starving myself, which tells you how elevated sugar prevents you to lose weight. I am not diabetic, my a1c 5.5. I has slight nausea and fatigue first 2 days and after that, it’s all gone and I never felt better, I have no cravings, I eat approximately 1000cal. A day and it’s more than enough, instead of contact thoughts of food I do other things that I USED to enjoy: exercise, etc. I am worried coming off ozempic before I lose all weight I need. It is a miracle drug for me! I hope it will help you all! If they keep working on meds like this it will reduce DT2 and obesity drastically"

10 / 10
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636 Report
  • Cheryl
  • Taken for less than 1 month
  • January 30, 2022

Ozempic (semaglutide) "I did lots of research before starting Ozempic, so was aware of potential (hideous) side effects. I started a week ago on a starting dose on .25. (Had my second .25 dose this morning). Super super super happy!!! Based on research, I have opted to inject in my upper leg rather than my tummy. I don’t know if it’s based on the injection location, or if I’m just lucky, but I have had ZERO side effects. No nausea. No dizziness. Nothing. I am eating three sensible, small, low fat meals a day, with (perhaps) a small amount of fruit as a snack, and walk my dog regularly. I am down 1kg (2.2 pounds) over the week, and am super confident that I will be able to continue on Ozempic until I get down to my goal weight (20kg/44 pound to go). Although my doctor said he will increase my Ozempic to .5 then 1mg over the next 2 months, I am going to say no, and stay on .25 for as long as that works for me. (Why increase if the current dose is working!). I am 55. Cost in Australia = $132 per script."

10 / 10
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279 Report

Frequently asked questions

  • Londo...
  • Taken for 1 to 6 months
  • January 8, 2021

Ozempic (semaglutide) "Having struggled with a need for carbs and sugar for over 2 decades it caught up with. Constantly sluggish, despite regular exercise. Risk of heart issues as have an inherited Cholesterol disease. Weight, well thats a given, most females postmenopausal struggle to lose weight. So, after all sorts of natural therapies and a ton of exercise nothing helped very much. My GP mentioned Ozempic, even though I was only pre diabetic she still felt it would help. After the usual low dose start -6 weeks later up to 1mg. I have been injecting weekly and 6 months later, I am not only 30 lbs down I feel so brilliant. More energy, better sleep and no sugar cravings at all. It has been great. No side effects, maybe a little constipation at the start (mainly due to change of eating habits) Superb med, wish more people could be offered the chance to use it. It is still expensive in the insurance world , however hopefully like many other meds in this country the costs will lessen."

10 / 10
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  • Aila
  • Taken for 1 to 6 months
  • January 4, 2021

Ozempic (semaglutide) "I went on Ozempic for weight loss after being told by a friend of mine about it - she started at 280 lbs and lost 60+ pounds. My whole life I’ve always been about 130 pounds, and then I rapidly gained 50 pounds within about 2 years. I started taking the ozempic at 182 pounds (I’m 5’4) and 6 months later I am down 25 pounds and continuing to lose. I could not recommend this drug more. It INTENSELY reduced my appetite and obsession over food. Aside from some occasional nausea (maybe once every 2 weeks), and some diarrhea, nothing that I can’t handle, the drug has been pretty great. This is only my experience though!"

10 / 10
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Are you taking this medicine?

  • Marsh
  • Taken for 6 months to 1 year
  • April 27, 2020

Ozempic (semaglutide) "Unbelievable medicine-although I was suppose to start w a .25 dose and move up to .5, I never did. I have stayed on the .25 dose and feel amazing. I have lost 30 lbs-don’t have any bad taste in my mouth, no bloating or excess gas. Actually I can’t find anything bad to say about this med other than it is expensive. Feel better than I have in years and my A1C is unbelievable! Keep it up but please make it cheaper!!"

10 / 10
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214 Report
  • Lizmon
  • April 20, 2022

Ozempic (semaglutide) "I can’t hold this back anymore as this medication has changed my life. For years I have been overweight, spend a lot of money buying tabs, shakes, diet plans, personal trainer.. you name it. My life was bad.. low self esteem. As a nurse for over 15yrs this was very bad for me. I have been taking ozempic for 7 months now and have lost 5st. It works like magic. I have to still watch what I eat, drink a lot of water and try to do minimum exercises. Ozempic change my life"

10 / 10
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104 Report

More FAQ

  • Tanner
  • Taken for less than 1 month
  • June 18, 2022

Ozempic (semaglutide) "I was so afraid to try this med because of all the bad reviews. I could not survive endless nausea or stomach issues. I just came here to say that I had none of these issues, and it is helping with cravings."

9 / 10
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94 Report
  • SooGirl
  • Taken for less than 1 month
  • July 8, 2021

Ozempic (semaglutide) "I've been on Ozempic for just over a week now as part of a physician-run weight loss program. I was told to expect some GI upset but I had no idea it would be this bad. 7 days after taking I started with diarrhea. One day after injection #2 (2.5mg) I was up all night with diarrhea, nausea, severe reflux, belching and eventually vomiting. Meds like Pepto can't seem to touch it. I am going to talk to the doc next week and see what he thinks. I really don't think it is worth this kind of suffering."

2 / 10
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117 Report
  • Grate...
  • Taken for 6 months to 1 year
  • June 15, 2022

Ozempic (semaglutide) "I went to my Doctor to talk about my weight at 59, 247 pounds, bra size 40J. Was going to get reduction. Start with .25 MG and I am up to 1mg and I have lost 60lb I am at 187. Still get cramps every now and then. Going to try giving it to me in my leg. Bra size 33G. Off 2 pills, have energy and self esteem again. It's a miracle."

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86 Report
  • Shirl
  • May 13, 2021

Ozempic (semaglutide) "I've been useing ozempic for a few months now but the constipation has been extreme, also I have been having severe cramping at night and very yellow urine (only since starting ozempic) l was told to drink more water, I got up to over 4 litres a day but still having severe cramping, has anyone else had these symptoms which aren't on the list"

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  • HPano
  • Taken for 1 to 6 months
  • June 11, 2020

Ozempic (semaglutide) "In June of 2019 I was prescribed Ozempic for the first time for weight loss. I was giving a sample in office and my prescription was sent to the pharmacy. My doctor was super optimistic and I had seen drastic results in someone else I knew, but had been warned about the nausea. I am insulin resistant, have PCOS, and had gastric sleeve in 2008. At the time I started the first .25 dose I weighed 191.2lbs. On the single pen, I did 4 weeks of .25 and 2 weeks of .5 doses. At the end of the 6th week, I weighed 173.8lbs. That’s 17.4lbs in 6 weeks! Of course then insurance denied covering it moving forward and I was unable to continue, but after a year, new bloodwork panels and some adjustments, somehow it has been approved so I have started it again today! Hopeful for the same results! Had been taking topamax/phentermine combo and was really disliking the pens and needle side affects along with the severe change in my tastebuds that it caused."

2 / 10
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119 Report
  • Nicky
  • October 25, 2020

Ozempic (semaglutide) "I’ve been on Ozempic for a year and have lost 62lbs. I’m at my goal weight!! Had trouble sleeping for the first few months, and would have some negative side effects when I increased my dose. But powered through and they went away. I was up to 1mg but have been able to reduce to .75mg. Super happy!!"

10 / 10
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105 Report
  • Jess
  • Taken for 6 months to 1 year
  • March 2, 2022

Ozempic (semaglutide) "Been taking ozempic since August 2021 (so just over 6 months now) I’m taking it for help losing weight, currently at the 1mg dose with no negative side effects. First month of taking ozempic is a challenge. You will probably feel like crap, but once your body gets used to it the medication works wonderfully. I’ve lost 45 pounds in 6 months, 15% of my body weight. As long as you calorie count this medication will definitely help. For me it curbs my appetite drastically and stops “impulse” buying junk food. It also helps with blood sugar, unlike with dieting alone I don’t get “hangry” which is amazing. Needle is tiny and does not hurt at all."

10 / 10
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68 Report
  • InMiami
  • June 15, 2021

Ozempic (semaglutide) "I just started Ozempic to help with weight loss. My first iunjection (0.25) was four days ago. I was nervous at first about injecting myself with anything. The needle doesn't hurt at all. I was also nervous about possible side effects after reading the reviews. I went through with it anyway and have had zero side effects. I'm pretty sure I've been eating less and haven't been as hungry. I think it has been curbing the hunger. I read one review that said to inject in the thigh, not the stomach, even though the instructions say either are fine, as well as the upper arm. My pharmacist recommended the stomach so that's what I did and I was completely fine. Here's hoping for some decent help with weight loss when used with eating better (and less) as well as some exercise. Make sure you refrigerate it. I didn't think to put it in the fridge until the next day and apparently my third pen (I got a 3 month supply) will have to be tossed which is very sad given how pricey this is."

10 / 10
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83 Report
  • Melissa
  • Taken for 6 months to 1 year
  • February 25, 2021

Ozempic (semaglutide) "I have been on Ozempic for weight loss for 10 months and I have lost 66 pounds!! This drug has been amazing. At first I had a few side effects which included nausea and constipation but they did resolve. I noticed almost immediately how much better I felt on this drug. Not only was my appetite significantly decreased I felt better overall sort of like my metabolism was more even and my body utilized what I ate more efficiently. I lost my work insurance in November and also lost the coverage for the Ozempic. This is the only downfall. I do have private insurance through health partners but not one cent is covered by them. The price per month is around $800. With results this good all insurance company’s should be covering the cost 100% because it will save them millions, billions, even trillions possibly in the future. If they were smart they would get behind this drug."

10 / 10
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89 Report
  • Lindy
  • Taken for 1 to 6 months
  • September 16, 2021

Ozempic (semaglutide) "70 years old, not diabetic but obese at 170 lbs, 5’2” tall female. Started weekly on 4/29/2021 and as of 9/16/2021 I am at 140 lbs. Cannot eat as much as I used to or I get nauseous. Slow loss, about 7-8 lbs a month. Plateau every so often and then lose 3 lbs immediately. Extremely happy with results."

10 / 10
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75 Report
  • vallen
  • Taken for 1 to 6 months
  • May 29, 2020

Ozempic (semaglutide) "I have been using this medication Ozempic for several months. My dose is 1mg per week. This medication has made me feel sick from my first dose. I've lost 15 lbs but have bloating, gas, burping, and most recently hiccups for over a week. I will not be using this medication anymore."

3 / 10
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101 Report
  • Dolls...
  • Taken for less than 1 month
  • April 15, 2021

Ozempic (semaglutide) "Ozempic side effects 6 months later after only one dose. I took only one dose and thought it was the end of me. It's 6 months later, I'm suffering the worst depression, I feel weak and shaky still, not sure how I can even function outside of the home. I was lucky to be working from home, but next week I go back to the office and I'm terribly afraid I won't even be able to make it from my car to the building. I really need something to fix this. Do not take this drug, I wouldn't have believed in if I didn't live it."

1 / 10
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79 Report
  • Glo
  • Taken for less than 1 month
  • September 23, 2021

Ozempic (semaglutide) "My doctor prescribed Ozempic last week and and weighed me at 200 lbs. On Sept 19, I took my first injection starting off at .25 mg. I was expecting some symptoms the next day but nothing appeared. I only had 1 meal on Monday and that's about it. Next following days I couldn't even feel hunger. I noticed that I have been eating less and less and I drink water LOTS of water to keep me full. I'm on my 5th day now and I'm now at 196.2 lbs. I AM AMAZED how this is really helping me. Next week, I am going to start my exercise. 30 min treadmill at least is my goal and work my way up. I'm going to get my 2nd injection on the 26th and I can't wait! This is working for me!"

10 / 10
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70 Report
  • Tanya
  • Taken for 1 to 6 months
  • May 12, 2022

Ozempic (semaglutide) "I have been taking Ozempic Since March 12, 2022. I started at the .025 dose for 4 weeks I had a little nausea but nothing serious and some constipation. Have now been on the .050 dose and have very little appetite and no other symptoms have remained other than occasional constipation I have to remind myself at times to eat. I have more energy then I have had in years and feel so much better in my clothes. Since March I have lost 25lbs. This has been a life changer for me as I feel so much better I am still 45 pounds from my goal weight but this drug has definitely helped me. I give the shot in my thighs as I have read many comments on here to do so for less symptoms and I believe that is why I have done so well."

10 / 10
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53 Report
  • Krissy
  • October 18, 2020

Ozempic (semaglutide) "I took Ozempic for 30 days and felt horrible most of the time with consistent headaches. I lost a few pounds due to not feeling hungry. I quit after the first month as my insurance didn’t cover the $2100.00 it cost for a three month supply. I have been off of it for two weeks and feel much better now. I have noticed it has slowed my digestion majorly which doesn’t sound like a good side effect as food can become very toxic if it sits in the body too long. I do not recommend this medication."

1 / 10
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76 Report
  • Gymkh...
  • Taken for 1 to 2 years
  • October 8, 2020

Ozempic (semaglutide) "My doctor prescribed ozempic to me a year ago for weight loss. I’m only taking 19 clicks every 2 weeks when I go see my doctor he gives it to me. Every time I get the Ozempic I get sick 2 days later. It starts by nasty burps, then stomach cramps, then out of nowhere I throw up you don’t get a warning, sometimes diarrhea and sometimes I feel like I’m going to pass out. I got the Ozempic Monday and woke up in the middle of the night with nasty burps and stomach cramps."

1 / 10
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71 Report
  • Dande...
  • Taken for 1 to 6 months
  • February 8, 2022

Ozempic (semaglutide) "I've been on Ozempic for two and a half months now for weight loss and the results have been great. I've lost about 25 lbs. The only thing I don't really like is I truly do have no appetite. At all. So sometimes eating is a slog. Just getting through 3 or 4 bites of a meal can be annoying. And even though it's been almost 3 months, I still get nausea from time to time. I also had to dial back a lot of my social drinking as I'm eating so little, there's nothing to absorb the alcohol in my stomach most days, causing indigestion, acid reflux, vomiting and other problems. Still, I'm going to stick with the medication to see how much weight I can potentially lose over the course of six months."

8 / 10
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  • Djour...
  • Taken for less than 1 month
  • July 17, 2021

Ozempic (semaglutide) "I was scared after reading some reviews- but wanted to share my experience so far. I began on.25 one week ago - I injected in my abdomen at night before reading about the thigh being better. The next morning I woke up with pretty bad nausea, but not vomiting - definitely enough though to prevent me from eating. All day I was lethargic and could not eat much. Each day it improved. It definitely does not allow you to eat heavily - eating very small meals is about all it allows and even then it does give you slight nausea initially. Took my 2nd .25 dose this evening and did inject the thigh. Hoping to update this in a few weeks- but it’s been manageable."

8 / 10
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52 Report

Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.

Learn more about Cardiovascular Risk Reduction