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Linaclotide User Reviews & Ratings (Page 5)

Brand names: Linzess

Linaclotide has an average rating of 6.6 out of 10 from a total of 890 reviews on Drugs.com. 56% of reviewers reported a positive experience, while 27% reported a negative experience.

Reviews for Linaclotide

  • Gottago
  • Taken for less than 1 month
  • November 26, 2019

Linzess (linaclotide) for Chronic Idiopathic Constipation "I took Linzess after being constipated for 4 straight days. I took it around 4:30 pm in the afternoon. By 6:30 pm my stomach was gurgling and rolling and by 7 pm I was on the toilet with explosive diarrhea. Everything but the kitchen sink came out of me. And let me tell you it felt great to get cleaned out. My stomach did not hurt. No cramping. Just lots of bathroom trips. Be sure to be at home when you take it. You'll go A LOT. Also drink lots of fluids because diarrhea like that can dehydrate you."

10 / 10
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  • Chel...
  • Taken for less than 1 month
  • June 21, 2019

Linzess (linaclotide) for Chronic Idiopathic Constipation "So I’m only on week two, but I have felt better than I have in a really long time!!! The first couple of days I took the 72 mcg and didn’t have a bowel movement yet. The third day I went up to the 145 mcg and I had a bowel movement two hours later! I took that for 4 days and now went back down to 72 just to see if it would work. I’ve been taking 72 since and I have a bowel movement every day. I experienced a little bit of diarrhea but nothing horrible. Nothing that kept me in the bathroom back and forth all day or for hours at a time like others have said on here. I have IBS-C, so I constantly felt bloated. I swear this medication reduced the bloating the very next day!! I felt so much better in general even though I hadn’t a a bm yet!! It works wonders for me! I’d highly recommend it!"

9 / 10
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  • JPano
  • Taken for less than 1 month
  • March 19, 2019

Linzess (linaclotide) for Irritable Bowel Syndrome with Constipation "I will never take this again! It works alright. Starts out as regular bm and then goes into diarrhea. Having diarrhea is one thing but when it gives you no warning and just starts flowing out, that's other. I've tried this for a few weeks; some days weren't too bad but the last time I took it at 5:30 a.m. and after about a half hour, it started to work. It was a nightmare. Though I was home I couldn't even make it to the bathroom. Later at about 9:30 thought it was ok and went to aerobics class and luckily I had a pad on as it started again. This med is too too harsh."

1 / 10
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  • tv200...
  • Taken for 1 to 2 years
  • December 19, 2015

Linzess (linaclotide) for Chronic Idiopathic Constipation "Totally life changing medicine for people with chronic constipation and straining. I only need one every 4 days to keep me regular now. It is not like other laxatives, this lasts for a couple days. It's really a great medicine for me, I think it could help many others!"

10 / 10
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  • msboj...
  • Taken for 2 to 5 years
  • March 5, 2019

Linzess (linaclotide) for Chronic Idiopathic Constipation "Linzess is awesome. I've had chronic constipation most of my life. This is the first thing that has worked! I take it and a couple hours later it starts clearing me out. No nausea. No cramping. I feel like a new person. No longer miserable. You will get diarrhea for an hour or so but it's worth not being sick and bloated all the time."

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  • KRA
  • Taken for 1 to 6 months
  • December 12, 2013

Linzess (linaclotide) for Chronic Idiopathic Constipation "I have Irritable Bowel Syndrome with constipation. My Dr. put me on Linzess 145. I was told to take it 30 minutes before my first meal. However, my schedule doesn't permit me to do so. I take it whenever my bowels are slowing down and I need some help (about once a week). Immediately I start feeling the effects, starting with gas, then painless bowels that I can literally feel my stomach emptying. On average It makes me go to the bathroom for 3 hours. It all depends on how much is in there. All in all, Love."

10 / 10
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  • Nny
  • August 22, 2015

Linzess (linaclotide) for Chronic Idiopathic Constipation "First off I would like to say that the majority of people not having a good experience with Linzess are not taking it properly. Following my doctors orders which were also labeled on the packaging from the pharmacy, Linzess 145mg works perfect for me. I have suffered from chronic constipation since I was a young girl and now I have a bowl movement every morning! A few things to keep in mind: Linzess takes 2 weeks to cycle through your body before it will work properly. Get through the 1st two weeks and it's great. I do have watery stools every morning. Always take it in the a.m. 30 mins prior to breakfast w/ a full glass of water. I allow 2 hours for Linzess to work through my system. So plan accordingly!"

10 / 10
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  • Anonymous
  • October 26, 2019

Linzess (linaclotide) for Chronic Idiopathic Constipation "I've had IBS C most of my adult life. I've struggled with bouts of several days of constipation followed by a bout of diarrhea as a cycle. My co-pay on Linzess is about $300 per month. My Dr. prescribed 145 mg Linzess and I took it a week before I could get it to work. That was a hard, painful week. After about 5 days of no results I tried taking two at a time as I read in some of the reviews and it finally worked. It worked so well in fact that use it every day. I normally take it as soon as I wake up with a glass of warm water and have a BM within 1 - 2 hours. I have been taking it every day for about 4 months now. I follow it with a teaspoon of Metamucil right after my BM. All in all I would say I'm 80% better off now than I was before. My main encouragement to others is GIVE IT TIME to get started. It could take a week of even more. After it does don't expect perfection. If you have lived with IBS C it could make a major improvement."

8 / 10
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  • Joshua...
  • Taken for 1 to 6 months
  • March 6, 2016

Linzess (linaclotide) for Chronic Idiopathic Constipation "Linzess has completely changed my life. I am a 28 yr old male who was constantly living with bloatedness and constipation. I would have very irregular bowel movements (once every 2 to 3 days on average) and was not getting enough sleep due to having a constant "dull" pain in my gut. I tried everything from cleanses, fiber, a cleaner diet, and also another drug (amitiza) for help. Nothing was working long term and I still felt drained of my energy. My doctor wrote me a prescription for Linzess (145mcg dose) and after day 1 I no longer felt bloated and after about a week my energy level was completely restored.I feel like a completely new person. Some minor diarrhea if taken later in the day. Nothing major though, no other side effects."

10 / 10
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  • JenMc
  • February 15, 2014

Linzess (linaclotide) for Irritable Bowel Syndrome with Constipation "I am 37 year old female who has been suffering from Irritable Bowel Syndrome-C for almost a year now. I went from having a bowel movement every 5 to 7 days to having one daily on this medication. I've been taking it for a month now and it started working right away. I do not have to run to the bathroom like some users have mentioned. You take it in the morning and about 30 to 60 minutes later it creates a movement. It has been so wonderful to feel "normal" again. However, the two draw backs I have noticed are, one, it doesn't really help with bloating (which is probably my main complaint), and the cost is an issue. I have three months of free samples then the cost is right around $200 a month."

8 / 10
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  • JMcLo...
  • Taken for less than 1 month
  • October 1, 2014

Linzess (linaclotide) for Chronic Idiopathic Constipation "I am a healthy type one diabetic who in November of 2011 completed my first marathon. That changed in May 2011 when I was diagnosed with gastroparesis. I've been hospitalized 32 times since then and suffer chronic constipation that, like every one else here, couldn't fix it. It is the most miserable feeling in the world. Clothes don't fit, painful itchy hemorrhoids that cause embarrassing bleeding through my clothes, and hours in the bathroom. I've been on the medicine for two weeks and it's an absolute miracle! I started at 290mcg and realized I could handle 145mcg. The lower dose allows me to have a regular schedule and no accidents. If I feel like I'm backing up at all I go to 290 for a day or two. "

10 / 10
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  • DC211
  • January 4, 2015

Linzess (linaclotide) for Chronic Idiopathic Constipation "Was prescribed Linzess for chronic constipation. Within 6 days I gained 7 pounds. When you're only 120 pounds, 7 is great! I'm an extremely active person and healthy eater. Thought it was water weight from the medicine, but been off the medicine for over a week and still weigh the same. Wish I had seen all the posts online about rapid and stubborn weight gain prior to taking the it!"

5 / 10
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  • LACon...
  • June 22, 2014

Linzess (linaclotide) for Irritable Bowel Syndrome with Constipation "Have had YEARS of irritable bowel syndrome with constipation. Bowel movement usually only twice per week...in and out of the bathroom for several hours, cramping and pain that would sometimes give me cold sweats. Then exhaustion and residual intestinal ache all day. No one understood. Fiber was useless. Several bouts of diverticulitis. Never realized that IBS and contipation could contribute to the development of diverticulosis. To me Linzess is a miracle. Yes you do need to be near a bathroom and the bowel motions are mostly liquid in this first 2 weeks I have been taking it. But NO PAIN, RESIDUAL ACHE OR EXHAUSTION! I can take it and go to work. Going out...just get up a little earlier. I even feel better and more energetic overall."

8 / 10
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  • Karen...
  • Taken for 1 to 6 months
  • January 28, 2017

Linzess (linaclotide) for Chronic Idiopathic Constipation "Has been a wonder drug for me! Have suffered from extreme constipation for years. Now have a regular bowel movement about 2 hrs after I take it. Took about 2 weeks to work so give it some time! Have never had the diarrhea side effect."

10 / 10
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  • Sunny
  • March 23, 2017

Linzess (linaclotide) for Chronic Idiopathic Constipation "This medication has been a great for me. I take it every morning (the lowest dose) on an empty stomach when I first wake up. I have had many years of chronic constipation and have tried MANY different things. This is the only thing that has really worked for me. Fortunately, I have not had the diarrhea issues that some people have reported. My doctor did say this can be a side effect for some. For others like me, it has worked great. Like any medication, there is always the chance you may have side effects and have to discontinue it. I think it's worth trying to see if it's right for you if you have had years of constipation that has effected your quality of life."

10 / 10
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  • Freedom
  • Taken for 1 to 6 months
  • May 17, 2019

Linzess (linaclotide) for Chronic Idiopathic Constipation "I first went to the doctor for constipation at the age of thirteen. I would have a bowel movement only a few times a month. It was a struggle to pass a bowel movement. The laxatives I took would hurt my stomach. Last year I had surgery to repair a hole in my colon. After surgery I stopped having bowel movements and the laxatives wouldn't help anymore. I started taking Linzess this year at forty nine years of age. Where have you been all of my life? Finally after using Linzess it is working I'm regular, no straining and no stomach pain. I feel great."

10 / 10
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  • Borel...
  • January 23, 2013

Linzess (linaclotide) for Chronic Idiopathic Constipation "I have had chronic constipation for twenty years.. I have tried everything. Zelmorm was the only thing I ever found that worked. As we all know they took it off the market in 2007.. I have been suffering ever since. Until now! I have only been on Linzess for two days and have had 3 bowl movements with no bad side effects. I'm excited about this new medicine. I'm hoping and praying it continues to work. Give it a try its definitely worth it. Good luck."

8 / 10
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  • Joano
  • April 26, 2021

Linzess (linaclotide) for Irritable Bowel Syndrome with Constipation "It does cause loose stool. I find the same day it’s loose the next day I take it I’m constipated. I have to push real hard to have a bowel movement. It feels like the loose stool is able to pass the collection of harder stool leaving behind more formed stool. I ended up in the hospital impacted. The stool had a strange odor."

2 / 10
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  • Elly...
  • February 13, 2016

Linzess (linaclotide) for Chronic Idiopathic Constipation "This drug has been a lifesaver. After having chronic constipation for years, I feel like a new person. Read the reviews and figured out how it would work best for me. I take the pill in the morning on an empty stomach every 2 to 3 days. I feel so much better now. I used to feel sluggish all the time having had one bowel movement a week. Believe me I tried everything imaginable before this so I was very happy when my gastro dr. suggested this drug."

10 / 10
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  • Mkano
  • Taken for 1 to 6 months
  • January 5, 2021

Linzess (linaclotide) for Chronic Idiopathic Constipation "Linzess did not work for me so my doctor doubled the dosage, and it still did not help with the constipation. It made me feel bloated. I went and saw a functional medicine doctor who recommended Restore. It comes in liquid form. I take one teaspoon with water or with a little prune juice and a couple glasses of water, and the constipation goes away."

1 / 10
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  • Pros...
  • Taken for 1 to 6 months
  • March 4, 2020

Linzess (linaclotide) for Chronic Idiopathic Constipation "Started with linzess dose of 72mcg; after 8 days doubled the dose to 2 capsules daily, wasn’t getting much relief with one capsule daily. Currently, on 145mcg dose. Have bowel movement daily and weight lost (pro). Experiences nausea, a lot of neuropathy and muscle pains (con)."

5 / 10
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  • compu...
  • Taken for less than 1 month
  • March 11, 2014

Linzess (linaclotide) for Chronic Idiopathic Constipation "I had abdominal surgery and was on opiods for the recovery period. I became constipated and finally gave in and took Linzess. It worked perfectly. I had a normal movement the next morning and had no side effects at all. As long as I take Linzess in the morning I am regular as clockwork."

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  • Becks
  • Taken for 1 to 2 years
  • October 16, 2023

Linzess (linaclotide) for Irritable Bowel Syndrome with Constipation "I have been taking Linzess for about two years now. Before starting it, I would have to take all the over-the-counter laxatives every day or at least once a week. I literally cannot go to the bathroom no matter what I do. I have IBS-C. Since starting Linzess, I have my quality of life back. I used to go to the ER all the time because of being so backed up and in serious pain. Now, I empty every morning and I have it down to a science. I drink a protein shake 30 minutes after taking it and it works great! I'm shocked at all the bad reviews, but I am guessing it is not the medicine for those people. All bodies are different. I love it and I am so grateful to be using it!"

10 / 10
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  • Gideon
  • December 17, 2019

Linzess (linaclotide) for Chronic Idiopathic Constipation "neurological side effects: I'm taking linzess 290 for more than 2 years. I suffered years from constipation and linzess solved the problem like kind of a miracle. The problem started few months ago. I started to feel "pins and needles" feeling. (the professional name is paresthesia). it started with the limbs, and later all over the body. I went to few doctors: neurologist, orthopedist, I did many checks (blood, EMG etc..) and all the results were normal. At the beginning no one connected it to linzess, because its not one of the known side effects but then one of the doctors suggested me to stop taking linzess for a few days. After 2-3 days all the neurological symptoms disappeared! Now I'm taking linzess 145. It solved the neurological problem but then I suffered a little bit from constipation so my doctor suggested me to add lactulose and now its ok."

8 / 10
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  • super...
  • December 18, 2013

Linzess (linaclotide) for Chronic Idiopathic Constipation "I just started taking Linzess 145 mg. My doctor gave me samples to try. The first few days I didn't notice anything, by the third day I finally cleared out my intestines, which was after almost a month of not having a real bowel motion. I actually stopped taking the medication for a few days because I was concerned I wouldn't be able to go anywhere, then started again today. In about 30-45 minutes I was in the bathroom. I'm not sure if I have to take it everyday or if I can skip a few days in between. I will ask my doctor. So far so good. Anything that helps me go is a miracle. I'm happy with once every several days especially because I am used to going every couple of weeks."

10 / 10
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78 Report

Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.