The following information is NOT intended to endorse drugs or recommend therapy. While these reviews might be helpful, they are not a substitute for the expertise, skill, knowledge and judgement of healthcare practitioners in patient care.
Unfortunately my experiences have not been good. It has reduced the seizures but, I get bad side effects - dizziness, lightheadedness, headaches, nausea and poor coordination.
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Vimpat has been doing a great job at stopping seizures. In fact I might even get to drive! However, it seems to cause great difficulty in remembering words and expressing ones self. Having previously been a great public speaker this is frustrating as now I cannot really talk without waving my hands around for a long time or saying "that one thing" or "uhhhhh". Typing is greatly slowed as I can't remember words. Forgetting things when not talking is also a problem. Problems with coordination are also apparent.
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Vimpat is highly effective at controlling my seizures. It causes dizziness at high doses, but this improves when lowering the dose of Lamictal, and greatly lowering the dose of primidone, which also causes dizziness. Vimpat is more effective at controlling partial seizures at high doses when it is nearly a primary medicine. My MD was the Director of Research in the Vimpat study. I have less dizziness at 600 mg/day when doses of other anti-epileptic drugs are lowered.
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When I started Vimpat I got vertigo, headaches, and nausea like woah. My neurologist asked me to try to stick it out, and I am SO glad I did.
It replaced Topamax (which was messing up my kidneys) and it works. I went a record (for me) 124 days without a seizure with the Vimpat/Keppra combination I am on now. I still get dizzy more easily than I used to, but seizure freedom is absolutely worth the inconvenience.
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I have been on Vimpat for about 6 months, adjunct to Zonegran. It has not helped to control my hormonal seizures yet, so my doctor keeps having to increase the dose of Vimpat. However, now I can't sleep well but feel really drowsy in the morning which doesn't help me at work, where I need to be very sharp. The worst is the chronic constipation. I am always bloated and have major abdominal discomfort since taking Vimpat.
Though not indicated in the literature, I found that a few days after starting the Vimpat titration kit I began to experience extreme soreness in the legs. It may not have been from the medication but I had not done any physical activity that would have caused such soreness in the muscles in my legs and lower extremities. Though I cannot say for certain that it was a side effect of taking Vimpat it does seem that the symptoms only emerged a couple of days after beginning the titration kit of Vimpat 50 mg twice a day leading to Vimpat 100mg twice a day. I am interested in sharing this to see if anyone else has had similar experiences because this is not a symptom listed in the medicine guide or any other lists of side effects of Vimpat.
I have found that this helps not only control the epilepsy but also lowers the amount of depression I tend to feel from the other medications I am taking.
Vimpat has some effectiveness for my partial seizures, but it is accompanied by other difficulties:
1. It gave me double vision early on. We had to balance my dosages of Vimpat and Lamictal to straighten out the problem.
2. I struggle with memory problems as a result of taking it. Sometimes I need to ponder extra long to even be able to recount what I did or learned just a few days before. And I'm not always successful.
3.Vimpat has intensified my emotions, especially in causing me to weep. I used to go a whole year without shedding a tear. Now I often can't even go a whole day without crying a bit. I don't think it's depression. I usually am moved to tears over something I deem wonderfully moving. Just totally out of character for me.
I have partial complex seizures and Vimpat has helped me not to go totally unconscious. I still have the auras, but don't have the "full blow" seizures where I do not remember anything. Weird thing is that I don't have the strong "full blown" seizures, but I have more frequent aura's. Don't know which is worse. It is safer for me not to have the actual seizure, but having more aura's during the day is scary too. Also, it seems like my memory is getting worse and I can't think of what it is I want to say. My mind goes blank on me especially when trying to think of the word I am wanting to say. My hair has dried out and have lost a lot of it too. Not sure if Vimpat is worth all this or not!
I have been taking Dilantin for almost 20 years. Tried all sorts of anti-seizure drugs. You name it I have it. Started Vimpat about 4/5 months ago along with Dilantin. 200mg/day. I felt initially that it is better than others. I did have short seizure (usually don't get frequently). With increased dose along with Dilantin I am confused, memory loss, dizziness, sort of depressive mood at times. Big thing is the memory loss. I forget what I did at work the other day, things like that. Feel very stressed and have become more sensitive . Major one is memory.
I am on Carbatrol and Keppra and added 400mg of Vimpat about 1 year ago. I do not beleive that my complex partial seizures improved over this time period. As side effects go its not a bad medicine at all, but I do not like the fact that I can't remember simple words in the English language and putting together sentences is a little more tricky.
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Data presented at the 65th Annual Meeting of the American
Epilepsy Society
• First presentation of pooled Vimpat® data showed a
decrease in partial-onset...
First presentation of pooled Vimpat® data showed a decrease
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