The following information is NOT intended to endorse drugs or recommend therapy. While these reviews might be helpful, they are not a substitute for the expertise, skill, knowledge and judgement of healthcare practitioners in patient care.
Vimpat (lacosamide) for Seizures: I had surgery in Jan 2013 to remove the right temporal lobe. My epilepsy changed altogether, I was just having daily partials but conscious when they happened. However after surgery things were really bad in terms of the quantity of seizures I was having. They were every 15 minutes!! Anyway I've now been on Vimpat for about 6 weeks and have noticed a huge improvement. I have gone from 40 partials to around 2-3 per day and so far no complex partials! However when I increased my last dose to 100mg twice a day, my heart was racing at 128 so had to reduce back to 50mg twice daily. I have noticed I am constantly itching and my memory is really bad. I'm not sure if this is because of the surgery or the Vimpat. I go back to work soon so really concerned.
Vimpat (lacosamide) for Seizures: I was on Keppra (500 mg/day) since Jan 2010, due to grand mal seizures from a brain tumor. No more seizures until Jan 2013, then another one. They added Vimpat (50 mg, 3/x day) & upped the Keppra (to 750 mg/day). I know the side effects are due to Vimpat- I never had them before, even on higher doses of Keppra. Extremely itchy skin- itching at my face and scalp constantly. Severe dizziness the 1st month, but that went away as I've adjusted. My vision suddenly got bad; like blurred/double vision. My vision was always 20/20 before this. Constipation which I've never had, but that's okay. Overall irritation and snappy moods. Overall okay.
Vimpat (lacosamide) for Seizures: I will be 50 next week so the hair loss may be due to menopause although I am having no other signs of this (still have regular cycles, no hot flashes, etc.). And this came on so quickly; as soon as I started taking Vimpat so I feel there may be a connection. Started 400 mg in November and had terrible insomnia/tremors so I was cut back to 300. I did not have a reduction in the number of seizures (4 partial a month) but the severity has reduced greatly. However my hair is falling out at an unbelievable pace. I am so happy for the reduction in seizure severity I will buy a wig if needed. Just wanted to mention for anyone else who may be facing this as it is not a listed side effect. Also 8 lb weight loss and still a bit anxious.
Vimpat (lacosamide) for Seizures: I am currently on 375mg Lamotrigine, and until recently, on 300mg Vimpat. My seizures reduced from one/month to one over a three month period, but still had frequent auras. My doctor increased my Vimpat to 400mg and I have not had a seizure in over 6 months and have had maybe only one aura. My seizures have started only in my sleep and it is a relief now to go to bed with out fearing that I will have a seizure. The only 'bad' side effect is the difficulty coming up with words. It's very irritating and does affect my job to some degree, but the tradeoff is worth it.
11 users found this comment helpful.
Vimpat (lacosamide) for Seizures: So far so good but I am just on it 3 weeks and only side effect is being sick to my stomach shortly after taking it then that eases up. Hard to think sometimes and I take it along with Keppra. Keppra took away the absence seizures but still had a severe grand mal once a month. I am hoping this will take care of that!
Vimpat (lacosamide) for Seizures: All I can say for sure is that I have not had a full outflopping on the floor seizure in almost a year, since being put on Vimpat. If I happen to forget a dose, I get very twitchy by that afternoon. So, with Vimpat, no seizures. Without Vimpat, I seize! Works great for me!
14 users found this comment helpful.
Vimpat (lacosamide) for Seizures: As a spouse of a Vimpat user I can tell you what I have observed. First on all it completely stopped the seizures. My wife has returned to work and is driving. She does not have depression or shows any physical side effect. However recently she has had some trouble sleeping and some memory problems. Nothing dangerous just annoying. She does have hormone rushes but we are not sure if it is from Vimpat or her age she is 54. So far this is the best medicine she has been on. When first diagnosed she tried others but they made her very depressed. She is a little short tempered but nothing we can't live with.
23 users found this comment helpful.
Review by ukgirl2012 (taken for less than 1 month):
Vimpat (lacosamide) for Seizures: I have started Vimpat just over 7 days ago and noticed I feel like losing marbles. I can't think straight, I can't concentrate on anything, can't read anything as can't concentrate long enough to read it. I get really dizzy, I'm forgetting lots, even walked out forgetting hadn't put shoes on. I was only started on 50mg one a day and within 7 days thinking it's making me a nutter.
17 users found this comment helpful.
Vimpat (lacosamide) for Seizures: This has helped control my complex partial seizures in combination with Neurontin, which I have been on since 1994. I have been on Vimpat for about 17 months now and it causes short/long term memory problems. I can't be on high doses of this. Sometimes I will be in mid-sentence and have to stop talking just trying to get the word(s) off the tip of my tongue. It also causes sleep problems and decreased appetite as well.
22 users found this comment helpful.
Vimpat (lacosamide) for Seizures: It really helped my seizures, but did not control them completely. I did not have any of the dizziness, but after being on it for a year and half I have really started to notice some things. My hair is falling out terribly bad. Not just on my head, but eyebrows and legs too. I have terrible itching and rashes on my arms and legs. This whole time I figured the memory problems were from the unsuccessful surgery, but now I think it is the Vimpat. It worked better than the other 10 medicines I tried before it, but the side effects are now bad enough that I need to change. The memory problems are terrible and not worth it if it does not control the seizures.
29 users found this comment helpful.
Vimpat (lacosamide) for Seizures: I am on Carbatrol and Keppra and added 400mg of Vimpat about 1 year ago. I do not beleive that my complex partial seizures improved over this time period. As side effects go its not a bad medicine at all, but I do not like the fact that I can't remember simple words in the English language and putting together sentences is a little more tricky.
14 users found this comment helpful.
Vimpat (lacosamide) for Seizures: I have been taking Dilantin for almost 20 years. Tried all sorts of anti-seizure drugs. You name it I have it. Started Vimpat about 4/5 months ago along with Dilantin. 200mg/day. I felt initially that it is better than others. I did have short seizure (usually don't get frequently). With increased dose along with Dilantin I am confused, memory loss, dizziness, sort of depressive mood at times. Big thing is the memory loss. I forget what I did at work the other day, things like that. Feel very stressed and have become more sensitive . Major one is memory.
27 users found this comment helpful.
Vimpat (lacosamide) for Seizures: I have partial complex seizures and Vimpat has helped me not to go totally unconscious. I still have the auras, but don't have the "full blow" seizures where I do not remember anything. Weird thing is that I don't have the strong "full blown" seizures, but I have more frequent aura's. Don't know which is worse. It is safer for me not to have the actual seizure, but having more aura's during the day is scary too. Also, it seems like my memory is getting worse and I can't think of what it is I want to say. My mind goes blank on me especially when trying to think of the word I am wanting to say. My hair has dried out and have lost a lot of it too. Not sure if Vimpat is worth all this or not!
32 users found this comment helpful.
Vimpat (lacosamide) for Seizures: Vimpat has some effectiveness for my partial seizures, but it is accompanied by other difficulties:
1. It gave me double vision early on. We had to balance my dosages of Vimpat and Lamictal to straighten out the problem.
2. I struggle with memory problems as a result of taking it. Sometimes I need to ponder extra long to even be able to recount what I did or learned just a few days before. And I'm not always successful.
3.Vimpat has intensified my emotions, especially in causing me to weep. I used to go a whole year without shedding a tear. Now I often can't even go a whole day without crying a bit. I don't think it's depression. I usually am moved to tears over something I deem wonderfully moving. Just totally out of character for me.
22 users found this comment helpful.
Vimpat (lacosamide) for Seizures: Though not indicated in the literature, I found that a few days after starting the Vimpat titration kit I began to experience extreme soreness in the legs. It may not have been from the medication but I had not done any physical activity that would have caused such soreness in the muscles in my legs and lower extremities. Though I cannot say for certain that it was a side effect of taking Vimpat it does seem that the symptoms only emerged a couple of days after beginning the titration kit of Vimpat 50 mg twice a day leading to Vimpat 100mg twice a day. I am interested in sharing this to see if anyone else has had similar experiences because this is not a symptom listed in the medicine guide or any other lists of side effects of Vimpat.
30 users found this comment helpful.
Vimpat (lacosamide) for Seizures: When I started Vimpat I got vertigo, headaches, and nausea like woah. My neurologist asked me to try to stick it out, and I am SO glad I did.
It replaced Topamax (which was messing up my kidneys) and it works. I went a record (for me) 124 days without a seizure with the Vimpat/Keppra combination I am on now. I still get dizzy more easily than I used to, but seizure freedom is absolutely worth the inconvenience.
33 users found this comment helpful.
Vimpat (lacosamide) for Seizures: I have been on Vimpat for about 6 months, adjunct to Zonegran. It has not helped to control my hormonal seizures yet, so my doctor keeps having to increase the dose of Vimpat. However, now I can't sleep well but feel really drowsy in the morning which doesn't help me at work, where I need to be very sharp. The worst is the chronic constipation. I am always bloated and have major abdominal discomfort since taking Vimpat.
29 users found this comment helpful.
Vimpat (lacosamide) for Seizures: Vimpat is highly effective at controlling my seizures. It causes dizziness at high doses, but this improves when lowering the dose of Lamictal, and greatly lowering the dose of primidone, which also causes dizziness. Vimpat is more effective at controlling partial seizures at high doses when it is nearly a primary medicine. My MD was the Director of Research in the Vimpat study. I have less dizziness at 600 mg/day when doses of other anti-epileptic drugs are lowered.
24 users found this comment helpful.
Vimpat (lacosamide) for Seizures: Vimpat has been doing a great job at stopping seizures. In fact I might even get to drive! However, it seems to cause great difficulty in remembering words and expressing ones self. Having previously been a great public speaker this is frustrating as now I cannot really talk without waving my hands around for a long time or saying "that one thing" or "uhhhhh". Typing is greatly slowed as I can't remember words. Forgetting things when not talking is also a problem. Problems with coordination are also apparent.
46 users found this comment helpful.
Vimpat (lacosamide) for Seizures: Unfortunately my experiences have not been good. It has reduced the seizures but, I get bad side effects - dizziness, lightheadedness, headaches, nausea and poor coordination.
31 users found this comment helpful.
lacosamide for Seizures: I've suffered from general and partial seizures for many years. Many medications which have been tried before have either had side-effects (some severe) or I have had a bad allergic reaction too. Lacosamide so far has only produced a drowsiness for around an hour when it kicks in, it has though reduced the partial seizures greatly and I have had no more general (or grand mal) seizures from the time I started taking this medication. However, I have noted that the drowsiness does seem to ease with time. Under medical supervision I would recommend you give it a bash as it seems to work for me.
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