The following information is NOT intended to endorse drugs or recommend therapy. While these reviews might be helpful, they are not a substitute for the expertise, skill, knowledge and judgement of healthcare practitioners in patient care.
Vimpat (lacosamide) for Seizures: Have been on Vimpat for about 4 months now and am now starting to understand the side effects thanks primarily to these reviews. Previously on Dilantin for >10 years for complex-partial seizures. The positive of using this mediicne is I have a marked improvement in my gums. The Negative side effects are as follows:
Poor memory/word recall/digging
Short term memory impairment/can't remember what just doing and wanted to do next.
Loss of the ability to focus and concentrate/easily distracted. Might not be entirely Vimpat related.
Burning feet/ MD. suggested it could be Vimpat related.
Some loss of taste, Impaired ejaculation.
Hope this helps. Might consider going back to Dilantin. Good first time medicine.
Vimpat (lacosamide) for Seizures: I've been having seizures for the last two years, after being free from seizures for 5 years after temporal lobe surgery. I've had a seizure about every three months. Each seizure was worse then the previous one. Last year when I fell complications caused kidney failure. This has passed. I was on Lamictal and Keppra was added, and both were increased, without any change in seizures. 4 months ago I was taken off Keppra and Vimpat was added. 600 Lamictal/400 Vimpat. It is a strong medicine, in the morning I got very dizzy and unbalanced with double vision. I complained and my dose was split up 3x a day and I feel much better. 4 months free of seizures now, I'm simply waiting for the next seizure, hoping not.
Vimpat (lacosamide) for Seizures: This has been the better of the 10 others we have been on with our young son. I will say that he has recently developed leg and lower back pain along with more frequent migraines and hair loss and a horrible rash on arms in legs. Also, some weight and memory loss along with some crying fits. But like I said, sadly this was the least side effects of all the ones we have been on. Topamax was the worst, it trashed his insides and turned my sweet child into a crying, crazy, cursing lunatic! Would love to know if anyone has had luck with less side effects on any other anti-epileptic meds. He goes several weeks so far without any seizures on Vimpat so far.
Vimpat (lacosamide) for Seizures: I have had grand-mal seizures since age of 15. Around 32 I started having partial seizures only I didn't know that's what they were till I read a pamphlet in my Drs office. They put me on Vimpat, which at first did not help with the dizziness I was already feeling from the partial seizures, but after about a year now the dizziness has definitely slowed and I only have partial seizures when I'm overly, overwhelmed, or stressed. It doesn't help with my grand-mal seizures which I have at least 1-2 every month. I have noticed weight gain, and memory loss which I had before the medication, and hair loss, and tingling in my limbs, but if I drink more water it helps with the tingling. As for the hair loss I take biotin and that has helped.
Vimpat (lacosamide) for Seizures: I take Tegretol and I have been on Vimpat now for over a year. At first I still had seizures but they were completely different to the ones I had before, I used to jump and scream, now I become an ironing board then kick legs. After a few months they stopped completely, I had never felt better, it was the first time in 25 years I had been free, but the last couple of months they have returned and I have never felt worse. Side effects: extremely emotional [which is at the other end of the scale from Vigabatrin which made me a nutter] depression, memory loss, stuttering and significant weight gain. I am much better on them than without, but as far as stopping my seizures it was short lived
17 users found this comment helpful.
Vimpat (lacosamide) for Seizures: Vimpat introduced 4 days ago at 50mg on top of Topamax (to be fazed out) and Tegretol. So far awful. Side effects are depression, lower back pain, mood is low, irritable, sad, day dreamy, tired, anxious. I don't feel like me anymore.
Vimpat (lacosamide) for Seizures: I drank all kinds of medications like Trileptal, Lamictal now I am on 3000 Keppra and still had seizures, but my doctor said don't do surgery I will give you Vimpat. 10% out 100 people took this and it helped. He was right I still had episodes even with 200mg Vimpat but it simply went away for about 6 months now. It does give you loss of hair and feeling depressed but also an important thing to do is watch what you eat.
16 users found this comment helpful.
Vimpat (lacosamide) for Seizures: My uncle has had epilepsy since he was 18. He is now 60. He was on Dilanton up until 4 years ago when he was put on Depakote after a 45 minute seizure. Then no more until February. Then he started having seizures once a week. The doctor added Keppra. The seizures kept happening every couple weeks so the doctor sent him to a neurologist which maxed out the doses of both pills. Last month he had 4 lengthy seizures within 2 hour time period. That's when the doctor added Vimpat. As of today he has not had a seizure but the doc wants to up the Vimpat again. Since he has been on it he has had horrible memory loss.
18 users found this comment helpful.
Vimpat (lacosamide) for Seizures: My 14 yr old son has been on Vimpat coupled with Keppra and although it is not recommended for children, it has given me peace of mind. He has been seizure free for over two years. Side effects appear to be minimal, he does have short term memory loss, like walking into the kitchen and forgetting why he came in there. He especially forgets chores, but I don't know if it's because of the medicine or because he is just a typical lazy teenager.
23 users found this comment helpful.
Vimpat (lacosamide) for Seizures: I have been on Keppra for a year and just started Vimpat 6 wks ago. The Vimpat seems to have controlled my simple partial seizures however, I have noticed the side effects are troublesome. Some of the side effects are shakes, depression, anxiety, mood swings, dizziness, but the most troublesome is the effect it has on my memory. It feels like I can't find my words or I've forgotten information I should know. I'm 50 years of age and have tried many different types of medication in the past 43 years for seizure control and Vimpat is working however the side effects on memory is affecting my job performance.
45 users found this comment helpful.
Vimpat (lacosamide) for Seizures: I had surgery in Jan 2013 to remove the right temporal lobe. My epilepsy changed altogether, I was just having daily partials but conscious when they happened. However after surgery things were really bad in terms of the quantity of seizures I was having. They were every 15 minutes!! Anyway I've now been on Vimpat for about 6 weeks and have noticed a huge improvement. I have gone from 40 partials to around 2-3 per day and so far no complex partials! However when I increased my last dose to 100mg twice a day, my heart was racing at 128 so had to reduce back to 50mg twice daily. I have noticed I am constantly itching and my memory is really bad. I'm not sure if this is because of the surgery or the Vimpat. I go back to work soon so really concerned.
27 users found this comment helpful.
Vimpat (lacosamide) for Seizures: I was on Keppra (500 mg/day) since Jan 2010, due to grand mal seizures from a brain tumor. No more seizures until Jan 2013, then another one. They added Vimpat (50 mg, 3/x day) & upped the Keppra (to 750 mg/day). I know the side effects are due to Vimpat- I never had them before, even on higher doses of Keppra. Extremely itchy skin- itching at my face and scalp constantly. Severe dizziness the 1st month, but that went away as I've adjusted. My vision suddenly got bad; like blurred/double vision. My vision was always 20/20 before this. Constipation which I've never had, but that's okay. Overall irritation and snappy moods. Overall okay.
20 users found this comment helpful.
Vimpat (lacosamide) for Seizures: I will be 50 next week so the hair loss may be due to menopause although I am having no other signs of this (still have regular cycles, no hot flashes, etc.). And this came on so quickly; as soon as I started taking Vimpat so I feel there may be a connection. Started 400 mg in November and had terrible insomnia/tremors so I was cut back to 300. I did not have a reduction in the number of seizures (4 partial a month) but the severity has reduced greatly. However my hair is falling out at an unbelievable pace. I am so happy for the reduction in seizure severity I will buy a wig if needed. Just wanted to mention for anyone else who may be facing this as it is not a listed side effect. Also 8 lb weight loss and still a bit anxious.
29 users found this comment helpful.
Vimpat (lacosamide) for Seizures: I am currently on 375mg Lamotrigine, and until recently, on 300mg Vimpat. My seizures reduced from one/month to one over a three month period, but still had frequent auras. My doctor increased my Vimpat to 400mg and I have not had a seizure in over 6 months and have had maybe only one aura. My seizures have started only in my sleep and it is a relief now to go to bed with out fearing that I will have a seizure. The only 'bad' side effect is the difficulty coming up with words. It's very irritating and does affect my job to some degree, but the tradeoff is worth it.
34 users found this comment helpful.
Vimpat (lacosamide) for Seizures: So far so good but I am just on it 3 weeks and only side effect is being sick to my stomach shortly after taking it then that eases up. Hard to think sometimes and I take it along with Keppra. Keppra took away the absence seizures but still had a severe grand mal once a month. I am hoping this will take care of that!
11 users found this comment helpful.
Vimpat (lacosamide) for Seizures: All I can say for sure is that I have not had a full outflopping on the floor seizure in almost a year, since being put on Vimpat. If I happen to forget a dose, I get very twitchy by that afternoon. So, with Vimpat, no seizures. Without Vimpat, I seize! Works great for me!
28 users found this comment helpful.
Vimpat (lacosamide) for Seizures: As a spouse of a Vimpat user I can tell you what I have observed. First on all it completely stopped the seizures. My wife has returned to work and is driving. She does not have depression or shows any physical side effect. However recently she has had some trouble sleeping and some memory problems. Nothing dangerous just annoying. She does have hormone rushes but we are not sure if it is from Vimpat or her age she is 54. So far this is the best medicine she has been on. When first diagnosed she tried others but they made her very depressed. She is a little short tempered but nothing we can't live with.
48 users found this comment helpful.
Review by ukgirl2012 (taken for less than 1 month):
Vimpat (lacosamide) for Seizures: I have started Vimpat just over 7 days ago and noticed I feel like losing marbles. I can't think straight, I can't concentrate on anything, can't read anything as can't concentrate long enough to read it. I get really dizzy, I'm forgetting lots, even walked out forgetting hadn't put shoes on. I was only started on 50mg one a day and within 7 days thinking it's making me a nutter.
32 users found this comment helpful.
Vimpat (lacosamide) for Seizures: This has helped control my complex partial seizures in combination with Neurontin, which I have been on since 1994. I have been on Vimpat for about 17 months now and it causes short/long term memory problems. I can't be on high doses of this. Sometimes I will be in mid-sentence and have to stop talking just trying to get the word(s) off the tip of my tongue. It also causes sleep problems and decreased appetite as well.
43 users found this comment helpful.
Vimpat (lacosamide) for Seizures: It really helped my seizures, but did not control them completely. I did not have any of the dizziness, but after being on it for a year and half I have really started to notice some things. My hair is falling out terribly bad. Not just on my head, but eyebrows and legs too. I have terrible itching and rashes on my arms and legs. This whole time I figured the memory problems were from the unsuccessful surgery, but now I think it is the Vimpat. It worked better than the other 10 medicines I tried before it, but the side effects are now bad enough that I need to change. The memory problems are terrible and not worth it if it does not control the seizures.
43 users found this comment helpful.
Vimpat (lacosamide) for Seizures: I am on Carbatrol and Keppra and added 400mg of Vimpat about 1 year ago. I do not beleive that my complex partial seizures improved over this time period. As side effects go its not a bad medicine at all, but I do not like the fact that I can't remember simple words in the English language and putting together sentences is a little more tricky.
28 users found this comment helpful.
Vimpat (lacosamide) for Seizures: I have been taking Dilantin for almost 20 years. Tried all sorts of anti-seizure drugs. You name it I have it. Started Vimpat about 4/5 months ago along with Dilantin. 200mg/day. I felt initially that it is better than others. I did have short seizure (usually don't get frequently). With increased dose along with Dilantin I am confused, memory loss, dizziness, sort of depressive mood at times. Big thing is the memory loss. I forget what I did at work the other day, things like that. Feel very stressed and have become more sensitive . Major one is memory.
42 users found this comment helpful.
Vimpat (lacosamide) for Seizures: I have partial complex seizures and Vimpat has helped me not to go totally unconscious. I still have the auras, but don't have the "full blow" seizures where I do not remember anything. Weird thing is that I don't have the strong "full blown" seizures, but I have more frequent aura's. Don't know which is worse. It is safer for me not to have the actual seizure, but having more aura's during the day is scary too. Also, it seems like my memory is getting worse and I can't think of what it is I want to say. My mind goes blank on me especially when trying to think of the word I am wanting to say. My hair has dried out and have lost a lot of it too. Not sure if Vimpat is worth all this or not!
53 users found this comment helpful.
Vimpat (lacosamide) for Seizures: Vimpat has some effectiveness for my partial seizures, but it is accompanied by other difficulties:
1. It gave me double vision early on. We had to balance my dosages of Vimpat and Lamictal to straighten out the problem.
2. I struggle with memory problems as a result of taking it. Sometimes I need to ponder extra long to even be able to recount what I did or learned just a few days before. And I'm not always successful.
3.Vimpat has intensified my emotions, especially in causing me to weep. I used to go a whole year without shedding a tear. Now I often can't even go a whole day without crying a bit. I don't think it's depression. I usually am moved to tears over something I deem wonderfully moving. Just totally out of character for me.
41 users found this comment helpful.
Vimpat (lacosamide) for Seizures: Though not indicated in the literature, I found that a few days after starting the Vimpat titration kit I began to experience extreme soreness in the legs. It may not have been from the medication but I had not done any physical activity that would have caused such soreness in the muscles in my legs and lower extremities. Though I cannot say for certain that it was a side effect of taking Vimpat it does seem that the symptoms only emerged a couple of days after beginning the titration kit of Vimpat 50 mg twice a day leading to Vimpat 100mg twice a day. I am interested in sharing this to see if anyone else has had similar experiences because this is not a symptom listed in the medicine guide or any other lists of side effects of Vimpat.
41 users found this comment helpful.
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