Skip to main content

Inclisiran User Reviews & Ratings (Page 2)

Brand names: Leqvio

Inclisiran has an average rating of 7.2 out of 10 from a total of 48 reviews on Drugs.com. 53% of reviewers reported a positive experience, while 9% reported a negative experience.

Reviews for Inclisiran

  • Jose
  • Taken for less than 1 month
  • May 15, 2024

Leqvio (inclisiran) for High Cholesterol "After about 4 days: nose bleed, sinusitis, sore lips and tongue. Feeling of exhaustion for a month. After 2 months, developed eczema and psoriasis on shins, and after a further week extremely itchy spots on trunk, arms, and legs. After month 1, cholesterol had reduced from 5.4 to 4.5."

7 / 10
Was this helpful?YesNo
1 Report
  • Jayne
  • Taken for 1 to 6 months
  • April 13, 2024

Leqvio (inclisiran) for High Cholesterol, Familial Heterozygous "I've just had my second injection. Cholesterol dropped, so that's a positive. I still have an injection site rash, possibly due to this last injection being very uncomfortable, unlike the first one. My IBS has been really bad this time too, but not sure if connected. Jury's still out as to whether I would have a 3rd."

6 / 10
Was this helpful?YesNo
2 Report
  • celine
  • Taken for 1 to 2 years
  • January 27, 2024

For High Cholesterol, Familial Heterozygous "I've had 3 injections last one early December, straight away it floored me, headache, blurred vision, feel weak al the time, muscle, joint pain, can't walk far so much pain in hips, shivers, like I had influenza all the time, quality of life, I was an energetic person I had this injection, on a positive side reduced cholesterol level in half, I'm due another injection in June 24, not having it, my life has changed so much, I'll take my chances in exchange for the quality of life to return to what it was!"

6 / 10
Was this helpful?YesNo
4 Report

Frequently asked questions

  • Anonymous
  • Taken for 1 to 2 years
  • September 14, 2022

For High Cholesterol, Familial Heterozygous "After a >99% occlusion of my LAD was detected I had a stent implanted at 43 years old. Untreated, my total cholesterol was at 360 mg/dl with LDL 260. Atorvastatin plus Ezetimibe did not lower the numbers sufficiently. Inclisiran was prescribed by my cardiologist in 2021, and 2 weeks after the first injection, my numbers are amazing. LDL has been below 55 mg/dl ever since. No side effects except for the rather painful injection. Amazing. Will undergo coronary radiography in 2024 to assess whether the good numbers translate into disease regression. (I'm from Germany where Inclisiran was approved in 2020.)"

10 / 10
Was this helpful?YesNo
11 Report
  • brr
  • Taken for 1 to 6 months
  • May 7, 2024

Leqvio (inclisiran) for High Cholesterol "Week after second dose. So tired don't want to get up from chair. Stiff leg muscles. Pain in back and hips. The medicine works well, bad cholesterol went from 112 to 43 in one month 49 after three months. Thankful for that but side effects are hard to deal with. Questioning the third dose."

6 / 10
Was this helpful?YesNo
1 Report

Are you taking this medicine?

  • Stacy
  • Taken for 6 months to 1 year
  • March 14, 2024

Leqvio (inclisiran) for High Cholesterol, Familial Heterozygous "I could not take statins without side effects. Sore muscles aching joints. I was crying at night, could not sleep. After using Leqvio for 2 doses, I don't even need to take any statins. I also changed the way I eat."

10 / 10
Was this helpful?YesNo
1 Report
  • revric
  • Taken for 1 to 6 months
  • April 26, 2024

Leqvio (inclisiran) for High Cholesterol "The Leqvio injection was a brief stop at the cardiologist's office. Typical, brief shot in the back of the arm. Easy. They held me there for ~15 minutes to ensure no injection symptoms. The nurse administering the injection did it very well. No pain or discomfort. I don't have serum numbers yet so I am unable to speak to the effectiveness, but I wish all my meds could be this easy."

9 / 10
Was this helpful?YesNo
0 Report

More FAQ

  • Divin...
  • Taken for 1 to 6 months
  • March 15, 2023

Leqvio (inclisiran) for High Cholesterol "I am having the most severe muscle pain and tight muscles I have ever had since I have been on Leqvio. Has anyone else had this?"

4 / 10
Was this helpful?YesNo
78 Report
  • Anonymous
  • Taken for 1 to 6 months
  • May 8, 2023

Leqvio (inclisiran) for High Cholesterol "Side effects, hives, itching, pain with urination, headaches, dizziness, blurred vision and sweating"

1 / 10
Was this helpful?YesNo
48 Report
  • Susan...
  • Taken for 1 to 6 months
  • May 25, 2023

Leqvio (inclisiran) for High Cholesterol, Familial Heterozygous "Have had significant hair loss. Pain in legs and knee joints. Both knees have cartilage and meniscus damage, with no previous history of knee injury or knee related issues."

4 / 10
Was this helpful?YesNo
37 Report
  • Eliot...
  • Taken for 6 months to 1 year
  • April 3, 2024

Leqvio (inclisiran) for High Cholesterol "About a month after Leqvio shot, I get heartburn, nausea, belly cramps, fatigue. Numbers are good, but not liking the side effects. Anyone else having similar issues?"

7 / 10
Was this helpful?YesNo
9 Report
  • David
  • Taken for 1 to 6 months
  • August 6, 2023

Leqvio (inclisiran) for High Cholesterol "Leqvio works very well to lower the LDL cholesterol, but I am having substantial weakness in my legs. No other side effects. Would hope there is some way to eliminate the weakness."

10 / 10
Was this helpful?YesNo
18 Report
  • Mlh
  • Taken for 1 to 6 months
  • March 12, 2023

Leqvio (inclisiran) for High Cholesterol, Familial Heterozygous "I had a terrible reaction to repatha so I requested Leqvio. I had my first dose 3 months ago and I haven't had any problems with it at all. I have my second dose scheduled in another 2 weeks."

10 / 10
Was this helpful?YesNo
23 Report
  • Anonymous
  • Taken for 6 months to 1 year
  • May 6, 2023

Leqvio (inclisiran) for High Cholesterol "Took first dose in October 2022. Bad cholesterol was 105 Second does in January Bad cholesterol was 45 in February. Cardiologist was amazed!! Feel much better this summer"

10 / 10
Was this helpful?YesNo
15 Report
  • Eliot...
  • Taken for 1 to 2 years
  • May 22, 2024

Leqvio (inclisiran) for High Cholesterol "Had high hopes, but too many gastrointestinal side effects. Also muscle pain and stiffness. Lowers cholesterol but 2 months after the shot, I still have side effects."

7 / 10
Was this helpful?YesNo
1 Report
  • roger...
  • Taken for 6 months to 1 year
  • May 19, 2024

Leqvio (inclisiran) for High Cholesterol "Not sure if this is related to Leqvio or not, however, since beginning the Leqvio regimen I have experienced an increased level of muscle and joint pain and reduced mobility."

6 / 10
Was this helpful?YesNo
1 Report
  • jack
  • Taken for 1 to 6 months
  • February 29, 2024

Leqvio (inclisiran) for High Cholesterol "Massive drop in LDLs with Leqvio. Medication was prescribed by my cardiologist, and Medicare with Supplementals paid for its EXPENSIVE costs."

10 / 10
Was this helpful?YesNo
2 Report
  • Thomas...
  • Taken for 2 to 5 years
  • January 1, 2024

Leqvio (inclisiran) for High Cholesterol "Worked for me, been taking it for a couple of years."

10 / 10
Was this helpful?YesNo
2 Report
  • shellie
  • Taken for 1 to 6 months
  • April 12, 2024

Leqvio (inclisiran) for High Cholesterol, Familial Heterozygous "Have felt better, not had blood work yet to check levels."

10 / 10
Was this helpful?YesNo
0 Report
  • lee
  • Taken for less than 1 month
  • November 27, 2023

For High Cholesterol "No problems at all. Took the shot on 9/27/2023. No side effects."

10 / 10
Was this helpful?YesNo
0 Report
  • Mary
  • Taken for 6 months to 1 year
  • April 18, 2024

Leqvio (inclisiran) for High Cholesterol "Leqvio helped me lower my cholesterol levels significantly. I cannot take statins because of the bone and muscle pain. However, I have bone and muscle pain even with taking Leqvio."

9 / 10
Was this helpful?YesNo
0 Report
  • Anonymous
  • April 15, 2024

Leqvio (inclisiran) for High Cholesterol "Lowest numbers I have ever had. Not aware of any side effects."

10 / 10
Was this helpful?YesNo
0 Report
  • L ham
  • Taken for 6 months to 1 year
  • May 28, 2024

Leqvio (inclisiran) for High Cholesterol "It has lowered my LDL. However, I have noticed that my skin started to wrinkle a great deal after my third shot. Has anyone else experienced this symptom? It is my only adverse reaction."

8 / 10
Was this helpful?YesNo
0 Report

Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.