Synvisc-One User Reviews & Ratings

• Carri...
• July 9, 2019

For Osteoarthritis "I had two prior series of Synvisc 1 injections and had some relief. I get lidocaine shot before each injection to help with pain. This third series has been awful. I have been in agony and have not been able to walk. My left leg calf muscles felt like they were being ripped apart. I was literally in tears daily. I did tell the medical staff of my pain. Third injection was almost two weeks ago and I am still in agony much of the time. Only when I have a full dose of prescription and OTC pain meds, plus lidocaine and other topical applications, in my system do I get relief. And I have to be very careful as to how I move, so as to not jar the leg and start the pain. I have been worse off than I ever was before."

• Fish
• Taken for 1 to 6 months
• June 10, 2019

For Osteoarthritis "I had a Synvic One shot on 4-16-2019 in my right knee. This isn’t the first time but it will be the last time. Today is 6-10-2019 and I still can’t bend it and limp terribly. I just want to cry. My quality of life has went down hill since I got this last shot. I called the orthopedic doctor who gave me the shot and I was seen last week and he was very short with me and said what did you expect you are bone on bone. You need a complete knee replacement. I asked for a sonogram or MRI to see if the medication had done something since I have had these shots before and worked wonderfully. He said "do you want pain meds" I said "no I want my old knee back". I ended with a prescription for steroids again. Never offered either test and I have private insurance. Lot # from injection 8RSL056. Maybe it’s time for a second opinion!!!! If anyone has anything that they have done to make your knee feel better please share."

• Jake
• Taken for 2 to 5 years
• May 2, 2020

For Osteoarthritis "I have mild to moderate osteoarthritis in my right knee from an ACL reconstruction in 2000 and menisectomy in 2016 to clean up meniscal tears. I have been using Synvisc One for over 2 years and it has been very effective. It takes me from having a stiff painful knee to a nearly fully functional joint that I can train and do fairly high impact sports on. It takes a week or 2 for it to kick in after an injection. Knee feels stiff and achy at first but it eases up and within a month you forget you ever had OA. With the single injection you are adding an extra 6 ml to the 6 ml already in your knee joint capsule. No wonder it feels full at first. Rest and give it a week or so to blend in. I am 56 and surf nearly every day. Synvisc-One is the miracle solution that keeps my knee pain-free and functional. I highly recommend it."

• Suzan
• Taken for 1 to 2 years
• February 21, 2020

For Osteoarthritis "I've been having Synvisc injections every 6 to 7 months for the past 2 years. Sometimes it's a rough couple of days with pain, swelling & trouble walking as I have it done in both knees. But once that's past I am almost pain free. I hope to push off a knee replacement for a few more years. I'll continue to get injections as they have made a significant improvement in the quality of life for me."

• ibeamys
• Taken for less than 1 month
• July 3, 2012

For Osteoarthritis "I had a knee injury over 10 years ago and was told that later on, I would have Osteoarthritis. Well that time is here along with bone spurs on front & back of my knee. Most times I would just live with the pain but at times when it was most unbearable I would be taking Advil sometimes every other day. When my brother told me he had this injection after an ACL injury and how great it was, I decided to give it a try since my insurance covered it, okay then. I won't lie, the initial injection was painful only because I hate needles and it is not a fast injection because of the fluid being so thick you can almost feel it going in and around your knee cap but I will tell you this is the best thing I ever did. No pain at all, going on 3 weeks."

• Jason...
• Taken for 2 to 5 years
• January 12, 2017

For Osteoarthritis "Having lost a quarter shape size of cartilage in my right knee, so bone on bone in that one and in the left knee advanced osteo which hurts more than the right, I know about pain. Synvisc is the best! I take 3 shots over 3 weeks ( 2ml per injection) and it lasts anywhere from 3-5 months. The lasting relief is that I don't get pain from walking or sudden nerve pains in the duration. everyone is different but I just get the shots done, no numbing..that's just silly cuz it's only a needle for God's sake. Yes, I sometimes get swelling after shots but reading some claims about "ruining my life" and "pain" is really foreign to me. I really like Synvisc, it greatly improves my quality of life. My advise is to "suck it up buttercup" get the shots."

• Dumitru
• Taken for 1 to 6 months
• August 26, 2020

For Osteoarthritis "The orthopedist recommended synvisc-one for O/A I have in my right knee. I also have patellofemoral osteochondritis. I read many reviews here, and decided to have it done xray guided vs just by hand touch to make sure the injection is precise. The radiologist put my knee in a certain position and went through the side, interior side of the knee, so the injection itself was successful and didn't hurt much like other wrote. The knee felt swollen for two weeks with some pain, but after that swelling went away, my old pain came back, the pain under patella. Today is 3 months and a half since the injection and I see no improvement. In conclusion it didn't help me at all."

• maple...
• January 27, 2015

For Osteoarthritis "Excess fluid was aspirated from my knee prior to SynViscOne injection. My doctor informed me that numbing was not recommended. Aspiration and injection were not very painful at all - just the initial "pinch." Swelling was minimal but pain lasted almost a week. 10 days into it, knee is feeling much better. I would do this again."

• Mari
• Taken for 6 months to 1 year
• May 6, 2020

For Osteoarthritis "Synvisc One definitely helped a lot for my Meniscus tears and osteoporosis. Initially I was a huge skeptic b/c nothing had helped me. I know that there are mixed reviews & risks. I’ve been an avid runner my entire life. I’ve had 2 meniscus knee surgeries. After the 2nd surgery, I didn’t experience relief. I couldn’t run more than a mile without pain (I’m only 25 years old!). I tried PT etc, didn’t help. After having Synvisc One, most of the days are now good and I can now run 5+ miles with minimal pain. It’s amazing. The downside is that I did need another injection after 7 months (but my insurance covers it). I don’t know if I’ll end up needing another. Even with the risks (educate yourselves!), I’m grateful I found something that works for my knee, even if it’s not a guarantee for the future. See a doctor who knows what they are doing, an orthopedic or regenerative medicine doctor. I have found seeing a good doctor is very helpful, especially if you have an adverse reaction etc."

• Sage...
• Taken for less than 1 month
• June 11, 2019

For Osteoarthritis "This was a terrible experience for me. I had the Synvisc injection and the next day I was super anxious and weepy. This anxiety lasted 7 days. I am normally none of those things. Over the next 2 weeks my knee was painful, stiff, and I had to use crutches to walk. The injection did not work and I will not have another Synvisc injection again."

• repub...
• Taken for 1 to 6 months
• April 27, 2016

For Osteoarthritis "I got this shot on march 17 2016,it was a preventative measure because my knee is bone on bone and I would get a cortizone shot every 6 months.24 hrs after the shot, my knee swelled up and the pain was incredible and I could'nt walk. 3 weeks later after having my knee drained and injected with medicine I had emergency surgery to flush out the synvisc. I've been out of work now for 6 weeks and with going to therapy am starting to walk a little better, I hope to return to work in 2 weeks.I had arthroscopic surgery 10 years ago on my other knee and the day after surgery I was much better than I am 6 weeks later after a preventive shot. be careful I think they are hiding all the bad reactions to synvisc"

• Martih
• June 25, 2015

For Osteoarthritis "I was so nervous about getting this shot - and believe me, it was a piece of cake! It was slightly uncomfortable for about 2-3 seconds, but no screaming pain. After a few days I did notice a reduction in pain. I am now about 4 weeks out from the shot and my knee feels wonderful! This shot has been totally worth it for me. I will get another one when needed with no hesitation."

• chrissy
• Taken for 1 to 6 months
• November 15, 2015

For Osteoarthritis "Going on 8 weeks after a synvisc one injection and the constant pain is now 10 times WORSE than before. my quality of life is horrible due to pain caused by shot. I have osteoarthritis in knee, nothing like the kind of pain I am in now. READ ALL THE REVIEWS BEFORE YOU GET THIS DONE"

• Airbo...
• December 16, 2011

For Osteoarthritis "I had orthoscopic surgery on both knees for meniscal turns from over use during my time in the military. After choosing the injections verses cortisones or steroid shots I've had excellent results. I'm 45 and still run 4 miles every other day without any pain. The injections were not painful and took only minutes in the doctors office. I finished two series and now ready for my third. I give it and excellent rating."

• Grmag...
• Taken for less than 1 month
• March 19, 2016

For Osteoarthritis "Had shot....shot was nothing...but 48 hrs. later I can barely stand the pain...elevating, ice, ibuprofen....but boy oh boy it hurts BAD. Gave birth to 3 children...one being breech....and swear this pain is worse.....I am hoping to be better soon....with this experience think I will not repeat this adventure. Do not think a knee replacement could be any worse than what I am going through right now!"

• John
• Taken for 6 months to 1 year
• January 20, 2015

For Osteoarthritis "Instead of giving me pain relief, it did the opposite. I went from moderate pain to severe pain. It has been 6 weeks and my condition is worse then before the injection. I'm hoping it wears off soon. When the PA gave me the injection, some fluid came out of my knee."

• Narci
• Taken for less than 1 month
• June 4, 2019

For Osteoarthritis "I have had bone on bone knees for many years and cannot have replacements since I have too many back problems to go through rehab. My knees have been in constant pain for at least 10 years and narcotic pain meds do little to help. I went for Synvesc One shot in each knee 6 days ago and the pain is so unbearable all I can do is lie in bed and cry. I am doing ice but no help. It feels like a knife stabbing my left knee joint and that’s bad enough but my right leg from thigh to calf feels like the muscle is being ripped apart. I have had 2 major back surgeries and have rods in my lower back and never had pain like this. Before the pain would keep me in bed with ice about 3 to 4 days but this time I hurt worse every day. Please be aware these injections work well most of the time but things can go horribly wrong for no rhyme or reason."

• Col...
• Taken for less than 1 month
• March 5, 2016

For Osteoarthritis "Was treated on 3/5/2016. The injection of Synvisc-One was painless and I felt immediate relief in my knee. Now, just hours later, I notice a greater range of motion for my leg and almost no pain in the knee joint."

• Robin...
• October 18, 2014

For Osteoarthritis "I had a Synvisc-One shot about 7 months ago in my right knee. The injection was not painful at all - just uncomfortable as the thick fluid goes in to the knee. I had pain relief for 6 full months. After this experience, I decided to get 2 shots - one in each knee. I had the shots done yesterday, and the pain from the shots was excruciating. The experience was nothing like the first time. I felt like I was going to pass out and as if I had been "sucker punched" in the gut. I couldn't get off the exam table for 20 minutes and could barely get in my car to drive home. I was in such pain and discomfort I went to bed and slept for 12 hours. Today, I still have discomfort and aching. "

• Daytr...
• Taken for 6 months to 1 year
• December 26, 2014

For Osteoarthritis "I've had both the cortisone shots and the Synvisc-One. I believe they were equally painful, the Synvisc maybe slightly more, as the fluid seems to be quite a bit thicker so there was noticeably more pressure. However, it's been well over 6 months and I haven't had any pain. I've recommended it for my father and would recommend it if the normal cortisone shots don't seem to work any longer."

• highd...
• Taken for less than 1 month
• July 8, 2015

For Osteoarthritis "This is day 2 after my first Synvisc One shot. The shot wasnt bad, only uncomfortble during the last 3 seconds. I walked out and had a little tightness as the gel was settling in. Day 2 Im walking around with absolutely no issues and with a 90% reduction in pain.Day 2 far exceeded all my expectations. I completely am pleased and satisfied with Synvisc One. I hope it lasts more than 6 months."

• Quazi...
• December 25, 2015

For Osteoarthritis "This was without a doubt one of the most painful experiences I have encountered in my 65 years. I had it last January. The shot itself was not bad, but immediately after the shot, the pain around the knee was excruciating. I pretty much lived with pain twice as bad as before I had the shot for the next eight or ten weeks. Staying off of it, icing it and pain killers were the only help. Eventually the pain slowed down, but I would recommend that people look carefully and study the possible side effects before doing it. I had a partial knee replacement in July (six months ago) and the results are spectacular... I am walking, doing water aerobics and extremely active without any pain."

• sacag...
• Taken for 2 to 5 years
• December 15, 2013

For Osteoarthritis "I have taken the Synvisc-One shot in both of my knees. It really does work and I am pain free for actually six months. The reason I will not take it now is because the last time I was given these shots it hurt just too bad. Now I am trying to find something else without all the more pain when taken."

• Marat...
• Taken for 6 months to 1 year
• October 6, 2015

For Osteoarthritis "I stopped running marathons, something I really enjoyed. My arthritis has put a stop to any running. Now, I walk 5-6 miles every other day with a pair of weights around my ankles. My arthritis kept me up at night until I started my Synvisc-One injections. I get one in each knee every 6 months; they really make a difference."

• mosta
• Taken for 6 months to 1 year
• October 19, 2014

For Osteoarthritis "I have had intermittent knee pain since I was a teenager. I am now 44 and a few years ago the knee pain began preventing me from running. I had my first Synvisc-One injection about a year ago. After reading about the studies online, which show mixed results, I was not expecting this to work but I thought it was worth a try. The procedure itself was only mildly uncomfortable. For about a week after my knee felt more irritated than usual...not terrible though. About a week later..no pain, lasted 4 months. Then the pain returned. My doc had me wait 6 months, and I had a 2nd injection. This one irritated my knee for a few weeks and I was afraid it had made it worse but after 3 weeks...pain free. Again lasted 4 months."