Skip to main content

Hylan g-f 20 User Reviews & Ratings (Page 5)

Brand names: Synvisc, Synvisc-One

Hylan g-f 20 has an average rating of 6.2 out of 10 from a total of 238 reviews on Drugs.com. 57% of reviewers reported a positive experience, while 35% reported a negative experience.

Reviews for Hylan g-f 20

  • Carol
  • Taken for 10 years or more
  • May 24, 2023

Synvisc (hylan g-f 20) for Osteoarthritis "I had the three-injection Synvisc 11 years ago with great results. Before the injections, I could barely walk from the pain of moderately severe OA in my right knee. I did a lot of researching and reading reviews and learned the importance of 1) finding a doctor who has lots of experience with knee injections, 2) asking for a pre-lidocaine type shot, 3) VERY importantly - keeping that knee elevated for a full 24 hours after each of the three injections and for the next few days do not walk any more than necessary as this allows the injected fluid to stay within the knee and not travel down to the calf muscle. I’m going to go through this process again for both knees soon. I hope to have such amazing success again."

10 / 10
Was this helpful?YesNo
5 Report
  • wife...
  • Taken for less than 1 month
  • August 1, 2016

Synvisc-One (hylan g-f 20) for Osteoarthritis "I had a SynVisc1 shot 10 days ago. Was so looking forward to it as the cortisone shot I had gotten before it lasted a short 2 months. I had tried earlier to have the shot but Wellmark Blue Cross and Blue Shield would not approve it til I tried other options. So then the cortisone was done. Then they approved it. It was a pain thru Wellmark. And a bigger pain when the SynVisc1 was done. Excruciating pain! Thought I was gonna pass out! Barely made it to my car. I am in much pain. Can't bend my knee. Shooting pain from tip of toe to butt. I am waiting impatiently. Some people say they got theirs done with an ultrasound guidance. I did not. I question if he hit the spot. He is one of the top orthopeds in Cedar Rapids. Said may take 30 DAYS!"

1 / 10
Was this helpful?YesNo
23 Report
  • Machaon
  • Taken for 6 months to 1 year
  • December 26, 2019

Synvisc-One (hylan g-f 20) for Osteoarthritis "For Osteoarthritis my Wife is , 74, has severe Bilateral primary osteoarthritis of knees. She had been on Euflexxa for the past few years. 4 months after injection her pain would get worse. We switched to Synvisc One. The Physicians Assistant explained that she has to feel for the soft spot adjacent to the knee cap to determine where to properly inject. My wife felt more pressure than she had experienced with the Euflexxa. She felt okay after the injection and was able to walk out of the hospital. After six months the Synvisc One was still giving her significant relief! She was due for another injection. About two weeks ago she received her second single injection from the same effective medical professional. We feel fortunate in having a Physicians Assistant who knows how to properly inject the Synvisc One. She is really happy with the results! It gives us hope that she can avoid a TKR for some time to come!"

10 / 10
Was this helpful?YesNo
15 Report
  • Tried...
  • March 2, 2017

Synvisc-One (hylan g-f 20) for Osteoarthritis "This injection is only effective if you have mild arthritis. If you have almost no cartilage left it is useless. I wish I had known this before I tried this injection. I have moderate-severe arthritis and got a week or 2 of relief."

1 / 10
Was this helpful?YesNo
21 Report
  • Nia
  • Taken for less than 1 month
  • July 12, 2018

Synvisc-One (hylan g-f 20) for Osteoarthritis "It is going on 4 wks and I have severe fluid build up I have called doctors office 4 times and was told to give it time to work ... what advice do anybody have this is making me depressed.. I had this injection on june 14th still no relief"

4 / 10
Was this helpful?YesNo
18 Report

Are you taking this medicine?

  • Bern...
  • May 15, 2017

Synvisc-One (hylan g-f 20) for Osteoarthritis "I too, had a similar experience. My first injection given to lateral knee site with mild stiffness and pain. My second injection given to inner part of knee with severe stiffness and pain, this was Wednesday. I called the doctor to report my symptoms and he prescribed Toradol on Friday same week. I've been limping struggling to get around with minimal relief and the swelling and stiffness is still there. I also had a low grade fever. It's now Sunday and I will be calling my doctor on Monday. I wondered if it was because of the different location, but I don't know. I watched a video on the internet by a doctor explaining and performing the injection procedure. He said the injection needs to be given in a very precise area of knee laterally preferred."

Was this helpful?YesNo
20 Report
  • Earl
  • Taken for 1 to 2 years
  • December 20, 2019

Synvisc-One (hylan g-f 20) for Osteoarthritis "I have had two Synvisc-One injections over the last two years. Bone on bone and 73 years old. Both have given me much relief and have lasted about 4-5 mos. The injection was done with ultrasound. I was in a great deal of pain before this last injection. Will do it again. Doctor said Medicare will only pay every 6 mos."

9 / 10
Was this helpful?YesNo
14 Report
  • Boo
  • Taken for 1 to 6 months
  • December 14, 2019

Synvisc-One (hylan g-f 20) for Osteoarthritis "I had a Synvisc One injection to my shoulder after MRI noted limited cartilage remaining, some tears and arthritis. It was uncomfortable to painful for 7-10 days and since then has been extraordinary. I have no pain and minimal discomfort with movement. I used to wake in pain during the night, but I am no longer bothered at all. I have gone back to powerlifting and am able to bench press with no problems. It has been incredible and is still effective five months in."

10 / 10
Was this helpful?YesNo
14 Report
  • jamai...
  • Taken for less than 1 month
  • June 23, 2017

Synvisc-One (hylan g-f 20) for Osteoarthritis "I had my first Synvisc-One injections in both knees 4 weeks ago. Had the recheck with the Ortho today. Pain improvement took 3 days. Some mild heat and swelling the day after but didn't last long. Injection site was a bit painful for about 3/4 days but completely tolerable. The Dr's projection is that I should get 6 months out of. These injections help me tremendously! My knees aren't 100% but never will be again anyway. My mobility and pain level improvement is easily 60% if not a bit more. I'm thrilled! Ortho specialist has recommended bicycle or eliptical as appropriate exercise. Very happy there has been this much improvement in such a short time!"

Was this helpful?YesNo
19 Report
  • Shera
  • May 21, 2019

Synvisc-One (hylan g-f 20) for Osteoarthritis "Just had my first injection of Synvisc-One yesterday. I have a high tolerance for pain but it was terrible. So sad I did not read reviews. Doctor said it could not make me worse and believe me the Synvisc-One has made my knee worse. I have much more pain and swelling then before along with the stiffness and popping. It’s horrible. I will not get the remaining two shots."

Was this helpful?YesNo
15 Report
  • Anonymous
  • July 30, 2017

Synvisc-One (hylan g-f 20) for Osteoarthritis "Had my first injection of Syn-visc 1 yesterday and have first total relief from knee pain in 10 years. The injection was not as painful as my cortisone injections. Hope I can stay pain free for a long time."

10 / 10
Was this helpful?YesNo
19 Report
  • Beegie
  • Taken for 2 to 5 years
  • May 7, 2019

Synvisc (hylan g-f 20) for Osteoarthritis "Synvisc has worked wonderfully for me with osteoarthritis in my left knee. For me it lasts over a year and makes me feel more stable in walking and standing. I have a sister who had it and it did not work for her at all (she also has Rheumatoid in addition Osteo arthritis though). It seems to have a cumulative effect too, I need the injections less often over time. Has been more than 18 months and I only now feel like I could use another injection.,"

10 / 10
Was this helpful?YesNo
15 Report
  • Anonymous
  • October 4, 2015

Synvisc (hylan g-f 20) for Osteoarthritis "I received one shot and was told I couldn't have another for 6 months. It's been 3 weeks with no relief from the pain. I am still limping significantly. Hoping it is just a matter of waiting longer for it to take effect."

1 / 10
Was this helpful?YesNo
22 Report
  • Pssda...
  • Taken for less than 1 month
  • August 6, 2017

Synvisc-One (hylan g-f 20) for Osteoarthritis "I am experiencing more pain 2 weeks post injection than I had prior to it. I have a great deal of stiffness. My knee is locked up and when walking will buckle under me. The injections are very painful, and the doctor must have irritated a nerve, because I'd have severe pain at the injection site from just brushing touch. Never, ever again!"

1 / 10
Was this helpful?YesNo
18 Report
  • big...
  • August 25, 2016

Synvisc-One (hylan g-f 20) for Osteoarthritis "After having a few cortisone shots and not much luck or longevity with them, my Dr asked me try the Synvisk 1and I was reluctant at first but when you have 100% bone on bone in one knee and 75% bone on bone in the other I was willing to try anything. I had to wait also to be approved by Wellness Blue Cross Blue Shield. It was finally approved and i had the shots in late July. I'm 49 yrs old and a bigger heavier man and I made my 15 yr old son come in to watch. It hurt like heck. My son was shocked to see me wincing in pain the entire time. It takes a little while to get it all in your knee as well. Then to my other knee I gripped the table and said my god nobody said they were this painful. Swelled up so bad for a week. Never helped me."

1 / 10
Was this helpful?YesNo
20 Report
  • audio
  • Taken for 6 months to 1 year
  • July 11, 2017

Synvisc-One (hylan g-f 20) for Osteoarthritis "2nd Shot of Synvisc in 8 months. I had worse knee pain and discomfort and develop severe muscle hip pain. A $1000 a shot!! I feel that originally I had minimal relief but feel that this drug is overrated. I had to have a Cortisone shot which gave me comfort and relief from severe pain and it was only $20! If need be I can get one every (3) months but most people will receive the injection every (6) months. A new drug is going to be released soon after it's trial and it is called Ampe. I am hoping that it will be successful. No one wants to get their knee replaced and it is a final result . . ."

Was this helpful?YesNo
18 Report
  • Angela
  • July 1, 2019

Synvisc (hylan g-f 20) for Osteoarthritis "Had the first of three synvisc shots last week. Since then I have had terrible pain in the back of my knee, going down to my foot. Last time I had these shots three years ago, had a good reaction. This time around I spend my days crying. Supposed to have second shot tomorrow unless the doctor can prove this is normal, I'm not having 2nd shot."

2 / 10
Was this helpful?YesNo
14 Report
  • She_s...
  • Taken for 6 months to 1 year
  • October 10, 2019

Synvisc-One (hylan g-f 20) for Osteoarthritis "I just had my second shot today for Bone on bone and osteoarthritis . The first one lasted 5 months and I waited for 7 to get another one. It took awhile to work but by the end of the first month I could run through the airport with no problem. Around the 5th month it wore off but overall I’m happy with it I had cortisone for years until they started to effect me hormonally and couldn’t get any more. I’m putting off surgery as long as possible, hoping they have some new technologies available soon."

10 / 10
Was this helpful?YesNo
13 Report
  • Dani
  • Taken for 1 to 6 months
  • March 31, 2019

Synvisc-One (hylan g-f 20) for Osteoarthritis "Had a scooter accident in Bali in 2011 landed my whole body weight on my right knee now I’ve been told I have Chondral degeneration So on 1/3/19 I had the synvisc-one injection done and the doc did a CT scan first but didn’t use an ultrasound guidance to inject. I’ve had the worst experience! This is worse than the accident I think! The pain has been horrendous I ended up on heavy steroids to reduce the fluid build up it was so bad I’m now pushing 5 weeks this Friday and still can’t walk for more than a few hours without it blowing my knee up again I finally thought I was getting better but still I’m suffering. I’ll never ever have another synvisc injection again Seeing knee specialist tomorrow to see if there’s something that can be done to help relieve the pain as I can’t tolerate anything more than anti inflammatories or panadol"

Was this helpful?YesNo
14 Report
  • prett...
  • Taken for 1 to 2 years
  • May 13, 2019

Synvisc-One (hylan g-f 20) for Osteoarthritis "I will never do Synvisc-One again. First injection got mild flu like symptoms. Some pain relief, a little better movement and some swelling for about 2 months. Six months later get second injection, got flu like symptoms again, only much worse along with swelling in my knee and no pain relief. Cortizone injections to help counteract the second injection only lasted about a month."

1 / 10
Was this helpful?YesNo
14 Report
  • Mrs...
  • Taken for 1 to 6 months
  • October 31, 2016

Synvisc-One (hylan g-f 20) "I had 4 rounds of Synvisc-One injections and took the last one May 31,2016 . It's been 5 months and I can barely walk .. I cannot straighten my leg and walk with a limp . These injections are not good. Wish I read reviews 1st. I Do Not recommend these injections at all . Wish I had just had the surgery"

1 / 10
Was this helpful?YesNo
19 Report
  • Fat...
  • Taken for 1 to 6 months
  • August 6, 2018

Synvisc-One (hylan g-f 20) for Osteoarthritis "I have bilateral knee osteoarthritis that responded well to cortisone, but after 3 courses, the relief only lasted 1 month. I chose synvisc-one (single injection) and just received my fourth dose. The previous injections lasted 6 months and they are a blessing! Yes, one dose has a lot of pressure, but you are done. I am one of the lucky ones who has virtually had no complications with any injections. I am back to playing pickleball after 48 hours! I strongly recommend synvisc-one when cortisone stops working; to delay surgery as long as possible."

10 / 10
Was this helpful?YesNo
15 Report
  • Purpl...
  • Taken for less than 1 month
  • September 27, 2018

Synvisc-One (hylan g-f 20) "I had the synvisc injection and exactly 30 days later my knee was swollen. Couldn’t bend, drive, barely walk. Dr ordered an MRI it was clear. Doctor drained my knee and said it was an allergic reaction to this gel injection. Started to swell again within the hour of having it drained. Call his office and was told this can happen and to just stay off my knee. Ice, ibuprofen. I just don’t understand how I can get an allergic reaction to something that’s been in my body for 30 days. This was a mistake I should have never tried this."

1 / 10
Was this helpful?YesNo
15 Report
  • Anonymous
  • Taken for 2 to 5 years
  • August 25, 2017

Synvisc (hylan g-f 20) for Osteoarthritis "I have been reading the reviews and I'm wondering if I got the same meds as, the folks who wrote these reviews. I got the shots in both, knees, not a numbing shot before the Synvis., Before shots it was very painful to even walk, needed a cane for some stability. The night of the first shots my knees we're tender but when my feet hit the floor the next morning I could not believe it. No pain, felt great. My Dr. Said that was very unusual. Pain subsides, over time not immediately. Received the series of 3 shots 4 years, ago this month. My knees are not as good as they were when I first got the shots but they are still better than before the shots. My doctor is surprised with results .I would advise anyone to go for the synvis injections."

10 / 10
Was this helpful?YesNo
17 Report
  • Minni...
  • Taken for less than 1 month
  • October 25, 2018

Synvisc-One (hylan g-f 20) for Osteoarthritis "I have had OA for many, many years. Have bone on bone with one clean up 20 years ago. Yes, I need replacements but trying to hold off. I had cortisone and they lasted, maybe a month. Three weeks and one day ago, I had Synvisc1 injections. Yes, they hurt. Yes, the left knee was swelled and painful. But....I woke up this morning, three weeks and one day since my injections..wow!! The pain has been reduced immensely. I can't say how excited I am! Doctor suggested I have a cortisone booster in January...I can do that!!!! I've read comments that some shots lasted 6-9 months. I'll take that. I am a caregiver for my husband and now I have some relief!!!"

9 / 10
Was this helpful?YesNo
14 Report

Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.