Fam-trastuzumab deruxtecan for Non-Small Cell Lung Cancer User Reviews

• Amy
• Taken for 6 months to 1 year
• October 27, 2023

Enhertu (fam-trastuzumab deruxtecan) "Fatigue is the worst side effect. So far, I have had 9 rounds. Tired all the time, but especially the week of treatment. Constipation and bloating the first week as well, but that is likely as much from the IV steroids as the drug itself. As far as results, no shrinkage of nodules for me, but no new growth, so we stay the course. The fatigue is worth it, at least at this point."

• Gary
• Taken for 1 to 6 months
• September 30, 2023

Enhertu (fam-trastuzumab deruxtecan) "Results very positive from CT scan (after infusion 4) bilateral Adenocarcinomas shrinking w/lymph nodes shrinking 50%. Hair loss after infusion 2. Minimal side effects through infusion 6. Some nausea experienced, intermittent side pain, increased fatigue noted after infusion 8."

• Amy
• Taken for 6 months to 1 year
• February 27, 2024

Enhertu (fam-trastuzumab deruxtecan) "I have had 14 rounds so far. Non-small cell lung cancer. As others have noted, fatigue the week of is pretty horrible. I have treatment on Tuesdays and often don't leave the house until Saturday evening. I try to work out, or at least walk, every day but there is usually one day the week of treatment that I feel like a train hit me and I can't do much more than watch TV or read (and nap). I lost most of my hair by round 4 or 5 - has not started to grow back. I get very constipated and bloated the week of treatment - that could be as much due to steroids given with the drug though. I am also much more sensitive to sunlight - as someone who rarely burns, this was a surprise. I don't know what else to attribute it to but the drug. I get tingling in hands and feet and swelling under my eyes, all of which goes away in a few days. The GOOD news is that it seems to be keeping cancer from spreading - so I will continue as the side effects (especially weeks 2 & 3) are manageable given alternatives."