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Wellbutrin XL User Reviews & Ratings (Page 5)

Wellbutrin XL has an average rating of 7.4 out of 10 from a total of 438 reviews on Drugs.com. 67% of reviewers reported a positive experience, while 15% reported a negative experience.

Reviews for Wellbutrin XL

  • gemin...
  • Taken for 1 to 2 years
  • November 10, 2012

For Depression "Wellbutrin XL has saved my life. I have been on this medication for 18 months and my only regret is that I didn't start years earlier. I did not realize that I have been depressed for nearly 20yrs and with that came many side effects which included a full blown eating disorder. I was a compulsive over eater that had nothing to do with willpower. It was more like an alcoholic or drug addict. I am so happy now and love my life. Thank you Wellbutrin XL."

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  • tiredgi
  • Taken for 1 to 6 months
  • April 20, 2020

For Major Depressive Disorder "Like most people with depression I have tried a lot of meds. But after a great deal of research I have found a great combination for myself. I refuse to take SSRI's due to zaps and sexual side effects. But when I combined Wellbutrin XL 150 mg with Sam-E 400 mg every morning, good things have happened. Depression is better and my fibromyalgia has subsided a great deal. Try it. You might like it. Just be cautioned, you may need something to help you sleep. But these two make you much more active."

8 / 10
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  • Vett
  • Taken for 2 to 5 years
  • June 9, 2014

For Major Depressive Disorder "Was very depressed and hadn't slept in 4 days. Was diagnosed with manic depression and insomnia. Was put on Wellbutrin XL and trazodone for sleep. They both have been a miracle for me. No side effects from either except for dry mouth."

10 / 10
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101 Report

Frequently asked questions

  • CLO
  • February 9, 2016

For Depression "I read a lot of people saying that it's not working all that well for them, although I see one point in common here, it's only been 2 weeks. On some people it takes a little longer. I would say at least 3 to 4 weeks to get the full effect. Sometime you have to take a higher dosage. I'm at 200 mg now, and I see a difference. Talk to your doctor is 150 mg is not working for you.At the same time I have to admit, that at the beginning it's really hard regardless...so give time. Good luck everyone."

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  • Happy
  • Taken for 1 to 6 months
  • May 28, 2023

For Depression "Wellbutrin (150 mg XL once a day) has saved my life. I have been taking it for about 5 weeks. After a traumatic breakup 8 months ago, I went from being the happiest person I know to someone struggling with severe depression and anxiety. 2 months ago, I was beginning to get a little better when I broke up with the same ex again and found out my best friend was dying in a few weeks. I had been reluctant to take antidepressants before but at this point, I really had nothing to lose. My only regret is that I did not go on Wellbutrin earlier. I have had zero side effects and I feel exactly like myself before depression. I don't feel like I'm on medication at all. I started feeling the effects only days after starting the medication which is cool too because I know SSRIs take a lot longer to kick in. The one downside is that you are not supposed to drink because it raises the risk of seizures. I still drink 1-3 drinks socially a few times a week though (not that I recommend) and I've been okay."

10 / 10
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Are you taking this medicine?

  • Hello...
  • April 30, 2016

For Depression "Today was the first day I have had to take this medicine, I have already experienced the dry mouth, & not really caring to eat. I am only 20 years old, I've made a lot of dramatic changes in my life in the past month, & I've dealt with depression for a while but was honestly scared to admit it. I have read very many reviews and I am nervous about it, but at the same time I'm pretty happy to see the positive reviews, I'm wanting to feel happy like I should, & do things I want to do without worrying about what thought will ruin my plans for that day. Prayers would be appreciated while I get use to being on this, & start learning if it's for me or not."

5 / 10
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  • Miche...
  • Taken for 1 to 6 months
  • February 24, 2015

For Major Depressive Disorder "I had a rough time starting young with major depression and anxiety since middle school. My freshman year I started taking Lexapro. It was the worst possible thing that could've happened to me. Worst side effects ever. I gained over 40 pounds. I was tiny and petite to being around 125 to 170. Tried switching from many multiple different meds, still gained weight. Then my doctor finally put me on Wellbutrin, started off with the low dose and didn't really help much. She upped me to 150. I had hyperglycemia and finally got over it and got off of metformin. I am starting to finally lose some of that weight and about to look great for senior year. I highly recommend this medicine. It makes me not hungry anymore. I'm so happy now!"

9 / 10
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More FAQ

  • Lorenzo
  • Taken for less than 1 month
  • April 15, 2023

For Major Depressive Disorder "I'm a 52 year old male that has suffered with long term depression for a the majority of my young and adult life. I came to terms with the fact that I must medicate in order to have a fighting chance. I called my doctor a few days ago and she recommended Wellbutrin based on my constant suicidal thoughts and battle with anxiety and depression. I was excited at the thought of "turning the page," of my life. I must say that I was absolutely surprised at how well and how fast Wellbutrin worked. I just can't express what a difference it's made in my personal life. Now I have a good chance of mending fences with family that I once ignored purposely due to my severe battle with depression. Only time will tell just how good Wellbutrin works - it's a beautiful start though! Wishing you all peace in your journey."

10 / 10
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  • Golfe...
  • Taken for less than 1 month
  • October 10, 2018

For Depression "I've been on and off of various antidepressants and although the SSRIs helped when my little brother passed, the side effects were dreadful but I also no longer wanted to move - slept all day and every day with no sex drive. Hello Wellbutrin! Honestly, it changed my life. I have so much energy, sex drive back, and lost 10 lbs. The only downside is I don't always sleep well - but not in a groggy tired sort of way - seem to just wake up in middle of night and feel like I could go to the gym or something, but I will work my way through this due to all the positive things that have changed,"

9 / 10
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  • penny
  • August 24, 2013

For Depression "Saying goodbye to Wellbutrin. Sadly I have to come off this medicine after 2 years. It worked well for me, my weight went down and my sex drive went up. However, insomnia got the best of me. I could never get more than 4 hours of sleep a night and 6 with an Ambien. The lack of sleep is taking a toll on me sadly. I recommend this medicine and hope you don't have the sleep issues that I did."

8 / 10
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103 Report
  • Kikit
  • Taken for 10 years or more
  • November 8, 2020

For Major Depressive Disorder "I've lived through alot of trauma, I have been on Wellbutrin XL for 10 years and recently stopped for 10 months. Today is my 6th day back on it and I am feeling less anxious about my circumstances in life right now. It has helped me daily get out of bed, control outburst, and overall keep moving forward. I would say I am lucky to have this medication."

9 / 10
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  • Mcgell
  • December 2, 2015

For Depression "I have been on generic wellbutrin XL 150mg for about a month and a half now. All I can say is that it is an interesting drug. I didn't want to really go on it because, while I have depression, it is not that bad. I was hoping to get on something to help my anxiety because that is way worse. Well the first 3 weeks I was on it were fine. I felt a little bit more energy and libido and no side effects. Then all of a sudden from week 3-4 I got extremely anxious, stressed, and angry. Everything made me angry. I can happily say that those side effects have passed and I now have none. These last 2 weeks have been great. Tons of energy and drive. Love cleaning now for some reason and I used to hate it."

8 / 10
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  • Anonymous
  • Taken for 1 to 2 years
  • February 6, 2021

For Depression "I've tried almost every other selective reuptake Inhibitor and a few different tricyclic antidepressants for moderate depression and severe anxiety. This Wellbutrin XL is the first one that hasn't increased my anxiety and has actually helped. Currently on 450mg extended release."

9 / 10
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  • sanac
  • Taken for 6 months to 1 year
  • May 26, 2014

For Depression "I started taking Wellbutrin XL 150mg once a day for the first two weeks, back in November. At first I noticed a slight change in my mood. the dr. bumped me up to 300mg once a day. I have gotten a lot better now, not depressed, angry, sad all the time. Also before I started taking this I was having awful anxiety attacks to the point where I`d black out and wake up vomiting, I was losing a ton of weight because I was so depressed I had no appetite. Although I haven`t experienced weight gain with this medication I still don`t have much of an appetite but I have gone back to my normal weight. Drinking while taking this makes the alcohol affect you a lot quicker than usual, also causes me to black out 98% of the time."

9 / 10
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  • Lala
  • June 4, 2014

For Depression "Added this on along with my Cymbalta 60mg & Abilify 1mg. Took 150mg per day for 2 weeks until I realized I had major suicidal thoughts and ideation. Just out of nowhere. Immediately discontinued and felt better in 2-3 days. Beware of sudden mood changes please! The only good thing about this medicine is that it absolutely kills your appetite- lost 13lbs in 2 weeks. Not worth dying over though- sanity before vanity!"

2 / 10
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  • eyede...
  • Taken for 6 months to 1 year
  • July 11, 2016

For Major Depressive Disorder "Wellbutrin XL has been great for me. I have been on it for a few months and have completely noticed the difference in my lifestyle and my libido. My doctor was giving me samples of the brand name but she ran out and my insurance wouldn't cover the brand. My Copay for the brand was $1300.00 I could NOT afford that so she reluctantly put me on the generic. It was HORRIBLE. Worst experience of my life. Worst side effects ever. Luckily I came across another Pharmacy and they fill your Wellbutrin brand name for $50 a month. It's been great! Back on Wellbutrin and feeling amazing!!"

9 / 10
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  • BVan
  • Taken for 6 months to 1 year
  • June 13, 2019

For Major Depressive Disorder "Wellbutrin worked very well for me and did so in a matter of weeks. I started at 150mg SR per day and felt somewhat better. When increased to 300mg XL I felt virtually normal. I don't know if it saved my life, but it certainly let me feel life was worth living. The only side effects I have had are slight weight loss and somewhat more energy. Both of these side effects are actually welcome."

10 / 10
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  • Impre...
  • Taken for 1 to 6 months
  • February 2, 2016

For Major Depressive Disorder "This has been a life saver! Totally changed my life. I have tried SSRI many kinds to deal with my MDD with horrible side effects/ only slight headaches with wellbutrin;) I am very pleased with the results. It's been almost 2 months no sludge on the brain!!! THANK YOU!! I am GRATEFUL!!"

10 / 10
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  • Guest
  • September 23, 2013

For Depression "I was on Lexapro, Effexor and Cymbalta to treat my depression. All of these meds affect sexual drive and cause a gain weight (20-30 pounds). I also had a hair loss on Lexapro, muscle pain on Effexor. My doctor gave me Wellbutrin brand samples for 2 weeks-150mg a day. Wow, I started to feel a difference on the second day, my mood was excellent, I had a lot of energy, I could feel a joy from little things. The only side effects were: constipation and no appetite at all. "

9 / 10
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  • AnonW...
  • Taken for less than 1 month
  • September 12, 2013

For Depression "I have been taking 300mg for a few weeks now and I have to say this medication has definitely improved my quality of life. Such a big change from when I was trying Zoloft, Celexa, Lexapro, etc. Wellbutrin XL helps control my gloominess, anxiety, and even my appetite. I am more motivated to do things during the day. The biggest side effect for me right now is that I am more snappy and aggressive when I get angry, hopefully that will subside."

9 / 10
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  • Pura
  • Taken for 6 months to 1 year
  • July 24, 2019

For Major Depressive Disorder "It took a month or so but honestly the best medication I've ever been on. I tried over 15 different things before and finally wellbutrin allows me to feel happy and depression is much more manageable. I will say side effect wise I have a decrease in appetite and have lost around 12 pounds in 4 months. I am also more easily angered based on my menstrual cycle."

9 / 10
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  • Anonymous
  • March 27, 2010

For Depression "I use Wellbutrin XL and it helps my bipolar disorder and adult ADD!! It gives me better focus, eases anxiety, keeps me from becoming enraged for no reason and helps me from getting depressed! I no longer scream at my family (very important) and I don't sit and cry for no reason anymore! This is a miracle medicine for me."

9 / 10
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  • Happy...
  • December 8, 2017

For Depression "So I've been on it for about a month and a half. I've had severe depression for a long time now. I was in a relationship I just couldn't step away from. After this medication I realized that I am better than that. I found the source of all my depression. I am going to leave him and start my life without him. I deserve better. Also, I am really different, it seems to help with my anger issues as well. Things that used to just piss me off, no longer bother me anymore. It's really nice to enjoy things other than my bedroom."

10 / 10
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  • PBano
  • January 6, 2020

For Depression "I was hesitant to take Wellbutrin due to the negative side effects I read about and I have never been on any sort of anti-depressant before. The first week was not good & had a lot of side effects the worst being a headache, ear pressure/pain, & flu like symptoms. Has it helped?.. I’m definitely not as weepy & a little more optimistic but it has not helped my anxiety much. I do have more energy. I still cry at times but not as long or much & I still have all my range of emotions & get annoyed with my family and worry about everything. I was hoping to lose some weight or for it to help increase my sex drive but nope..no positive side effects for me.I guess I was expecting Wellbutrin was going to do much more but maybe my dose is too low or I need more time. I am not prepared to deal with further side effects of a med increase but I guess I will just have to take it day by day & see what it brings. Just not sure about it yet and & hoping for more...."

6 / 10
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  • Mac
  • December 11, 2019

For Major Depressive Disorder "I started taking 150mg about two years ago quickly went up to 300mg. My motivation went back to a normal level and I started painting, drawing and cooking again. My only issue was that I started getting daily headaches (after I had been on it for six months). My doctor put me on 150mg which got rid of the headaches, but my motivation got worse. I felt like I could do things I couldn’t when depressed, but also like I needed to convince myself to do anything extra. My doctor then gave me 5mg of lexapro on top of the Wellbutrin and its good. Recently got my blood work done for being fatigued, sleeping a LOT and brain cloudiness - its because I have a severe vitamin D deficiency. I highly recommend getting your bloodwork done if you feel like this suddenly loses effectiveness. A low vitamin D level can also cause depression which probably made it harder for me to feel better even on medications. Also look into getting this prescription from walmart, it is apparently $9"

8 / 10
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Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.