Acetaminophen / diphenhydramine for Insomnia User Reviews

Brand names: Tylenol PM, Percogesic Original Strength, Midol PM, Pain Reliever PM, Headache Relief PM, Unisom PM Pain, Non-Aspirin PM Extra Strength, Percogesic Extra Strength, Bayer Select Max Strength Night Time Pain, ConRx PM, Acetadryl, Night Time Pain, Genapap PM, Mapap PM, Counteract PM Extra Strength, Wal-Nadol PM Extra Strength, Excedrin PM, Headache Formula PM, Legatrin PM, Tylenol Sore Throat Nighttime, Pharbetol PM Acetaminophen PM Extra Strength Robitussin Honey Severe Cough, Flu + Sore Throat CF Max Nighttime Anacin PM Aspirin Free …show all brand names

Acetaminophen / diphenhydramine has an average rating of 6.3 out of 10 from a total of 32 reviews for the treatment of Insomnia. 56% of reviewers reported a positive experience, while 31% reported a negative experience.

Acetaminophen/diphenhydramine rating summary

6.3/10 average rating

32 ratings from 33 user reviews.

Compare all 85 medications used in the treatment of Insomnia.

10		28%
9		16%
8		13%
7		0%
6		3%
5		6%
4		3%
3		6%
2		0%
1		25%

Reviews for Acetaminophen / diphenhydramine

Insom...
Taken for 10 years or more
June 6, 2019

Tylenol PM (acetaminophen / diphenhydramine) "I have used Tylenol PM for a long time to help me fall asleep. Unlike Benadryl, this med actually keeps me asleep as well. However, the BEST effect from Tylenol PM is the dreams. I have had the most wonderful dreams."

10 / 10

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67 Report

Jonat...
Taken for 1 to 6 months
September 10, 2020

Tylenol PM (acetaminophen / diphenhydramine) "I have severe back pain everyday. Just had back fusion surgery in May. It's difficult to get comfortable at night in order to fall asleep. However, after taking two Tylenol PM (the recommended dose) within the hour I'm comfortable enough to doze off. I stay asleep for 6-10 hours most nights. Without it I would maybe get a few hours a night if I was lucky. Hope it works well for everyone else!"

9 / 10

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42 Report

agape...
April 28, 2016

Tylenol PM (acetaminophen / diphenhydramine) "The Tylenol PM worked .... TOO GOOD! After 20 minutes I would have a great night's sleep. I have been taking it for years .... then my son told me the new reports about this causing dementia. I stopped immediately. The side effects after I stopped have been pretty severe. I never dreamt that there would be withdrawals from this until I googled it but I have most of the symptoms (except for the shakes and nightmares).... dizzy, light headedness, nausea, unable to sleep. After all I thought, since I talked to my doctor over and over about them (and he said no problem) and they were over the counter, I was good. WRONG! Bad stuff. Tell everyone you know to stop them."

3 / 10

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69 Report

Winnny
January 26, 2013

Tylenol PM (acetaminophen / diphenhydramine) "I've been taking this med - or just the Benadryl, which is the sleep inducing part of Tylenol PM - for several years now, as needed. It definitely helps me to fall asleep more easily when I might otherwise lay awake for an hour or two. I did notice that it seems to loose its effectiveness somewhat if I use it too frequently. I've had no noticeable side effects."

8 / 10

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78 Report

Anonymous
October 24, 2012

Tylenol PM (acetaminophen / diphenhydramine) "When I take this medication I sleep through the night with no pain but wake up restless and feeling anxious and nervous all day. Also I get heart palpitations and difficult breathing. You have to be careful with this over the counter medication."

1 / 10

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76 Report

Are you taking this medicine?

Idk
Taken for 1 to 6 months
March 10, 2023

Tylenol PM (acetaminophen / diphenhydramine) "I’ve been taking Tylenol PM for about three months now and it works very well. Almost too well. I’ve been told by my mother that it was very difficult for her to wake me up for school and I kept saying “too early… too early…” and I never had any recollection of saying all that. At one point she thought I was dead because I was asleep in one position for way too long. This stuff is no joke. Now I depend on it for sleep and I stay up all night if I don’t take it before bed. I also tend to feel very shitty the next day. I shake and tremble a lot and I can never truly focus and I forget things too easily. I recommend to be extra careful with this stuff. It’s very easy to depend on and if you use it for awhile you’re going to end up feeling crappy 24/7. I’ve also been experiencing stomach issues. Please be careful with this!"

10 / 10

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12 Report

Cyd
Taken for less than 1 month
May 16, 2020

Tylenol PM (acetaminophen / diphenhydramine) "It’s pretty effective at helping me sleep, I’m down for usually 10-12 hours. I usually get bad side effects from any medication I’m on, so here are the ones I’ve had. Feeling lightheaded, numbness in feet and legs, heart palpitations, blurred vision. Some of this may be my existing medical conditions but it’s worth mentioning. I don’t think I’d recommend taking this for a long amount of time?? I’m only using it to help me through the rest of school."

4 / 10

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30 Report

Brook...
Taken for less than 1 month
September 6, 2020

Tylenol PM (acetaminophen / diphenhydramine) "I am delirious after taking Tylenol PM. Super hot, mind racing in a tortured/exhausted state. Have not stopped sweating can't get comfortable. Amplified exhaustion. Not bad enough for urgent care and too messed up to operate a car."

1 / 10

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27 Report

BritTex
September 29, 2008

Tylenol PM (acetaminophen / diphenhydramine) "I've taken other prescription sleep medications in the past but they do tend to make your drowsy and have all sorts of side effects. I suffer from rheumatoid arthritis and the pain stops me from sleeping. I now take this at bedtime with a small dose prescribed codeine. Between the painkillers and the "sleep" effect of the Tylenol, I truly can't believe how well I am sleeping! Just be aware that this can really make you fall asleep fast so do be ready for bed. I've spoken to four other people who have various pain problems and they all love this medication too."

10 / 10

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64 Report

Sarah
Taken for 1 to 2 years
August 15, 2018

Tylenol PM (acetaminophen / diphenhydramine) "Well I take this on & off, especially when we are low on melatonin or I can't simply sleep on melatonin. Some nights I can't sleep with taking it, and I take both. Then it may take me a bit to actually fall asleep but I usually sleep 10/12 hours on it! My daughter told me she couldn't get me up the other day, I told her I remember her saying something to her & she was like yah but you wouldn't get out if bed. "

5 / 10

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27 Report

Auntj
Taken for less than 1 month
January 5, 2017

Tylenol PM (acetaminophen / diphenhydramine) "I will never take this again. Woke with such a dry mouth I could barely swallow, and a need to use my inhaler. This is NOT a usual thing for me. Reading today, I see that anyone with asthma etc should not use this. I would echo that. I did sleep but still feel unwell and glad I only took TWO."

1 / 10

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32 Report

Anonymous
March 15, 2012

Tylenol PM (acetaminophen / diphenhydramine) "I really like this pill besides the fact that I sleep all day. I take the pill every few days at about 12, when I'm not tired and 15 minutes later I become drowsy. About 30 minutes after that, I'm asleep. but I tend to sleep really late. I don't hear my alarms and I can't get myself out of bed. If you do take this I would consider taking it earlier than you normally would. Other then that this pill is the best I have found and works great just like it says."

9 / 10

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45 Report

dogsg...
Taken for 1 to 6 months
July 26, 2012

Tylenol PM (acetaminophen / diphenhydramine) "This medicine works well for me as a sleep agent and also reduces the itching from mosquito bites. However, I have to be careful when I take it because it seems to last for a couple of days. The "withdrawal" from it the next day includes increased pain."

10 / 10

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32 Report

Hey
Taken for less than 1 month
December 15, 2021

Tylenol PM (acetaminophen / diphenhydramine) "I just started working third shift and use this when I get home to fall asleep. It works great and I get 8 hours of uninterrupted sleep. I don’t seem to wake up super groggy either. I am 21 years old so this may be the reason."

9 / 10

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8 Report

Babs
Taken for less than 1 month
January 4, 2022

Tylenol PM (acetaminophen / diphenhydramine) "Works great for pain and awesome for sleep! I haven’t the slightest idea how anyone can say this doesn’t help as a sleep aid…and I never feel groggy in am. I take it 15 minutes before I close my eyes."

10 / 10

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6 Report

imjus...
Taken for 1 to 2 years
April 16, 2013

Acetaminophen PM Extra Strength (acetaminophen / diphenhydramine) "I have body aches. I'm only 21 and falling apart and I have a real hard time getting to sleep, so I take one or two of these at night depending on my tiredness or achiness, and about 30 minutes to an hour I'm pretty much asleep and almost always stay asleep for 7-9 hours. I normally wake up with no achiness and feeling like I got a pretty decent nights rest. "

9 / 10

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17 Report

fleajo
September 20, 2013

Excedrin PM (acetaminophen / diphenhydramine) "I love these. When I feel like I will have trouble sleeping, I take 1 pill. That usually works. If it doesn't I take another one. No side effects except sometimes my dreams are better. No hangover. My sister can not take them, they make her groggy."

8 / 10

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11 Report

Anonymous
March 19, 2008

"I don't normally like to take pills for anything unless it's prescription for a real reason but when I need to sleep, I use these. I took one the other night and knocked me out cold, only 1. I have to cut 1 in half so I don't wake up sleeping."

10 / 10

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4 Report

Amanda
Taken for less than 1 month
February 27, 2020

Tylenol PM (acetaminophen / diphenhydramine) "this stuff didn't work ! Kept me up all night and I was thinking one hundred thoughts per minute ...."

1 / 10

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33 Report

Pony...
Taken for less than 1 month
April 12, 2015

Tylenol PM (acetaminophen / diphenhydramine) "Amazing made me sleep the whole night while I had insomnia. I give it a 2 thumbs up"

10 / 10

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50 Report

Kris
Taken for less than 1 month
August 12, 2019

Tylenol PM (acetaminophen / diphenhydramine) "Helped me fall asleep when I had severe sinus infection, and helped me sleep through the night."

10 / 10

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30 Report

Jayrret
April 20, 2016

Tylenol PM (acetaminophen / diphenhydramine) "Mom took it for years and it caused her to have dementia!! Do not take it long term!!!!!"

1 / 10

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39 Report

Insom...
Taken for less than 1 month
April 18, 2020

Tylenol PM (acetaminophen / diphenhydramine) "It made me very down to be honest but still I tossed and turned for hours before I eventually got about 2 hours sleep"

5 / 10

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18 Report

Anonymous
January 15, 2012

Tylenol PM (acetaminophen / diphenhydramine) "The last several times I have taken this I have become itchy and restless all night."

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36 Report

patty
Taken for 1 to 2 years
March 16, 2018

Tylenol PM (acetaminophen / diphenhydramine) "it helps me sleep but I still wake up, and feel tired for awhile"

8 / 10

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20 Report

Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.