Clinical Trial News Archive
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News Archive for March 2010
March 1, 2010
- Actelion Pharmaceuticals Ltd (CH) - BUILD-3 study with bosentan in idiopathic pulmonary fibrosis does not meet primary endpoint
- Landmark Head-to-Head S.A.F.E. Study Comparing ActiveCare+S.F.T. to Lovenox Published in Journal of Bone & Joint Surgery
- Theratechnologies Announces Publication in JAIDS
- European Data Suggest Switching Patients to IgPro20 May Significantly Reduce Drug Administration Volume
- New Data Show IgPro20 Delivers Highest Available Subcutaneous Ig Concentration with Tolerability Comparable to Current Treatments
- IgPro20, the First 20 Percent Subcutaneous Immunoglobulin, Demonstrates Efficacy against Infections While Maintaining Tolerability in Patients with Primary Immunodeficiency
- (Update) SCAI Statement on the CREST Study Findings: Carotid Stenting Is as Safe and Effective as Carotid Surgery in Patients at Risk for Stroke
- Neuroimaging Technique Supports Reduction in Amyloid-Beta in Brains of Patients Suffering from Alzheimer's Disease Treated with Bapineuzumab
March 2, 2010
- Kalbitor (ecallantide) Data Presented at American Academy of Allergy, Asthma and Immunology Annual Meeting
- HalcyGen Pharmaceuticals -- Successful Outcome from European Clinical Pharmacokinetic Study Comparing SUBA-Itraconazole with Sporanox
- Icagen Reports Results of Phase Ib Pain Study of ICA-105665
- Data from Two Phase III Studies of Merck's Investigational Asthma Drug Presented at American Academy of Allergy, Asthma & Immunology (AAAAI) Annual Meeting
- Genetic Immunity Presents DermaVir at DNA Vaccines 2010 Conference ? Unique Nanomedicine Formulation and Topical Administration of an HIV/AIDS Therapeutic Vaccine
- Peer-reviewed Articles Further Define Clusterin and the Role of a Clusterin Inhibitor, OGX-011, for the Treatment of Cancer
- Study Shows C1-Esterase Inhibitor Concentrate Rapidly Relieves Acute, Successive Attacks of Hereditary Angioedema at All Body Sites
- Surveys Reveal High Frequency of Prodromal Symptoms Prior to Acute Hereditary Angioedema Attacks
- Merck Reports Results of Phase III Study of Investigational Oral Allergy Immunotherapy Tablet (AIT) in Patients Ages 5-17 with Grass Pollen Allergy
March 3, 2010
- Pfizer And Medivation Announce Results From Two Phase 3 Studies In Dimebon (latrepirdine) Alzheimer's Disease Clinical Development Program
- Herceptin and Tykerb Effective Against a Subset of Gastric Cancers
- If You Take Simvastatin To Control Cholesterol, Watch Out For Infection Says New Report
- PTC Therapeutics and Genzyme Corporation Announce Preliminary Results from the Phase 2b Clinical Trial of Ataluren for Nonsense Mutation Duchenne/Becker Muscular Dystrophy
- pSivida Reports Presentation of Additional Positive 24-Month Data from Iluvien Phase 3 FAME Study for Diabetic Macular Edema at Angiogenesis 2010
- HIV Vaccine Strategy Expands Immune Responses
- Patient age not a factor in use of second-line therapy for lung cancer
- Anavex comments on failure of Pfizer and Medivation's Alzheimer's investigational drug Dimebon during Phase 3 clinical trials
March 4, 2010
- Cabazitaxel Increased Survival for Patients with Advanced Hormone-Refractory Prostate Cancer
- Raptor Pharmaceutical Announces Publication of Data Supporting Potential Efficacy of WntTide(TM) in Treatment of Triple-Negative Breast Cancer
- Dendreon Presents Updated IMPACT Results Confirming Provenge Improves Overall Survival in Patients With Metastatic Castrate-Resistant Prostate Cancer
- Stelara and Remicade Data in Treatment of Plaque Psoriasis to be Presented at American Academy of Dermatology (AAD) Meeting
- Negative Phase III Trial Results for Latrepirdine (Dimebon)
- Argos Therapeutics Publishes Positive Immune Response, Safety and Manufacturing Data for its Arcelis? HIV Program in Clinical Immunology
- Beta Blocker Therapy Underused in Heart Failure Patients
- Presentations on Geron's Telomerase Inhibitor At AACR Special Conference
March 5, 2010
- ADVANCE-2 Study Results Demonstrate Investigational Anticoagulant Apixaban Was Statistically Superior To Enoxaparin In The Prevention Of Venous Thromboembolism Following Knee Replacement Surgery
- Phase III REGION-I Study Shows PEP005 (ingenol mebutate) Gel 0.05% May Reduce Pre-Cancerous Skin Lesions in Patients with Actinic Keratosis
- Open-Label Study Supports Long-Term Efficacy Of Xenazine (Tetrabenazine) For HD Chorea
- Experimental Vaccine Protects Monkeys Against Chikungunya
- Researchers Report that Thymosin beta 4 Improves Neurological Function after Stroke
- Common Osteoporosis Drugs Are Associated With a Decrease in Risk of Breast Cancer
- Poniard Pharm Presents Positive Survival Data from a P2 Study in Metastatic Prostate Cancer
- Poniard Pharmaceuticals Presents Positive Survival Data from a Phase 2 Clinical Study of Picoplatin in Metastatic Prostate Cancer at the 2010 American Society of Clinical Oncology Genitourinary Cancers Symposium
- Scientists Find New Form of Prion Disease that Damages Brain Arteries
March 8, 2010
- Genmab Announces Results from Zalutumumab Phase III Study of Refractory Head and Neck Cancer Patients
- Recentin Did Not Meet Primary Endpoint in Horizon III Study in Metastatic Colorectal Cancer
- New Imiquimod Formulation for Actinic Keratosis published in JAAD
- Argos Therapeutics Presents Positive Phase 2 Data of its Arcelis Personalized Immunotherapy Platform in Metastatic RCC at ASCO GU Symposium
- Millennium Announces First Clinical Data For TAK-700 Prostate Molecule at ASCO GU
- Nektar Announces Positive Phase 2 Clinical Data from First Stage of NKTR-102 Study in Women with Platinum-Resistant Ovarian Cancer
- Omthera Pharmaceuticals, Inc. Closes a $6.5M Series A led by Sofinnova Partners to Advance Epanova, a Prescription Omega 3 Therapy
March 9, 2010
- Nektar Announces Positive Prelim. Data for NKTR-102 in Ovarian Cancer
- INSYS Therapeutics, Inc. Announces Positive Phase III Efficacy Trial Results for Fentanyl Sublingual Spray
- Warfarin Users Appear More Likely To Develop Brain Bleeding Following Stroke Treatment
- Inhibitex to Present at Two Upcoming Conferences
- BioMimetic Therapeutics Presents Promising Pre-Clinical Sports Medicine Data at the 2010 ORS Meeting
- Mayo Researchers Link Obesity to Worse Outcome in Patients Being Treated for Colon Cancer
- New Data Presented at American Burn Association's Annual Meeting Support Safety Profile of RECOTHROM Thrombin, Topical (Recombinant) in Pediatric Patients
- Genomic Health Announces Publication of Study Using Oncotype DX(R) in Node-Negative and Node-Positive Breast Cancer Patients Treated With Aromatase Inhibitors
- Acologix Presents Data on Cartilage Regeneration by AC-100 at the 56th Annual Meeting of the Orthopaedic Research Society
March 10, 2010
- Medicine to Lower Blood Pressure Significantly Decreases Risk For Cardiovascular Disease, Stroke
- AM-Pharma presents positive results for Phase II trial in Acute Kidney Injury
- QLT Announces Phase II Clinical Trial Results and Development Plans for the Punctal Plug Delivery System
- Research Findings Expected to Ease Treatment of Low Neutrophil Counts in Cancer Patients
- ImmunoCellular Therapeutics' Dendritic Cell-Based Vaccine Demonstrates Statistically Significant Increase in Survival in an Animal Model of Glioblastoma
- Limerick BioPharma Announces Positive Phase 1a Data for LIM-0705
- BioAlliance Announces Positive Preliminary Results in the First Phase I Clinical Trial of fentanyl Lauriad
March 11, 2010
- Access Pharmaceuticals Reports Significant Oral Bioavailability of Cobalamin(TM) Oral Insulin in Additional Studies
- Allon's Phase 1 trial broadens davunetide's intranasal safety and dose range
March 12, 2010
- Pfizer Discontinues a Phase 3 Study of Figitumumab in Previously Treated Patients With Advanced Non-Small Cell Lung Cancer
- Two Phase 3 Trials of Sunitinib With Commonly Used Chemotherapies in Advanced Breast Cancer Did Not Meet The Primary Endpoint
- Tranzyme Pharma's Clinical Results on Ulimorelin (TZP-101) Selected for Oral Presentation at the Distinguished Abstract Plenary Session of Digestive Disease Week 2010
- Genentech Provides Update on Phase III Study of Avastin in Men With Late Stage Prostate Cancer
- BioSante Announces Positive Leukemia Vaccine Results
- Novel stroke treatment passes safety stage of UCI-led clinical trial
- Baxter Presents Clinical Efficacy Results from Phase III Study of Seasonal Flu Vaccine
- PolyMedix Presents PMX-30063 Antibiotic Data at 8th World Congress on Trauma, Shock, Inflammation and Sepsis ? TSIS 2010
- ASBMR Task Force Reviewing Link Between Fractures and Bisphosphonate Therapy
March 15, 2010
- Abbott Statement: ACCORD Lipid Results Support Treatment Guidelines for Fibrate Use
- Inspire Announces Results From Azasite Phase 2 Blepharitis Trials and Plans to Continue Clinical Development in Anterior and Posterior Blepharitis
- Novartis International AG (CH) - NAVIGATOR Shows valsartan Delayed Progression to type 2 diabetes in at-risk Cardiovascular Patients with Impaired Glucose Tolerance
- Landmark Accord Trial Finds Intensive Blood Pressure and Combination Lipid Therapies do not Reduce Combined Cardiovascular Events in Adults with Diabetes
- Alnylam and Collaborators Present New Pre-Clinical Research on RNAi Therapeutics Targeting PCSK9
- Portola Pharmaceuticals and Merck Announce that Phase 2 Study Showed Investigational Factor Xa Inhibitor, Betrixaban, Reduced Incidence of Bleeding Compared to Warfarin in Patients with Atrial Fibrillation
- Intensive Lipitor Therapy Was Associated With Reduced Risk of Cardiovascular Events In Two High-Risk Patient Groups
March 16, 2010
- Viron Reports Positive Proof of Concept Results in Arthritis for its VT-346 anti-TNF Therapeutic
- Cytheris Announces Publication of Preclinical Study in Journal of Immunology Showing Interleukin-7 PromotesT Cell Viability, Trafficking, and Functionality While Improving Survival in Sepsis
- Single Short Course of Tolerx's Otelixizumab Provides Prolonged Preservation of Beta Cell Function
- Novartis International AG (CH) - Exploratory Trial Shows No Incremental Benefit Of Aliskiren Add-On Therapy In Improving Changes to Cardiac Shape In Heart Attack Patients
- Icagen Reports Positive Results for ICA-105665 in Patients With Photosensitive Epilepsy
- Study shows superior efficacy for Taxus Express Stents at one year compared to bare-metal stents in diabetic patients experiencing heart attack
- AMAG Pharmaceuticals, Inc. Announces Data Presentation at the National Kidney Foundation (NKF) 2010 Spring Clinical Meeting
- Mipomersen Phase 3 Study in HoFH Patients Featured in The Lancet
- Dabigatran etexilate shows greater reductions than warfarin in stroke in patients with atrial fibrillation across all stroke risk groups
- Positive Long Term Data Presented at ACC 2010 Demonstrate Sustained Safety and Efficacy Advantages of the CYPHER Sirolimus Drug-Eluting Stent over the Endeavor Zotarolimus-Eluting Stent
- XOMA 052 Prevents Adverse Cardiac Remodeling in Animal Model of Heart Attack
- Kuros Meets Primary Efficacy Endpoint In Phase Iib Study With Kur-111
- Data Highlights Involvement of Immune System in Response to Provectus's PV-10 Therapy and Its Role in the Bystander Effect
- PCI Biotech Holding (NO) - Successful completion of the third dose group in the Amphinex study. Continued good tolerability and strong tumour response is reported, with an apparent high treatment specificity for cancer cells
March 18, 2010
- PERSEUS Trial Results Demonstrate Positive Safety and Efficacy Outcomes for Boston Scientific's Novel Platinum Chromium TAXUS(R) Element(TM) Stent System
- Advaxis Research In ActA Shows Therapeutic Anti-Cancer Response
- Desmoteplase enters clinical phase II in Japan in ischaemic stroke representing Lundbeck's first clinical programme in Japan
- [OctoPlus N.V. (NL) - OctoPlus announces publication of positive Locteron interim Phase IIb data
March 19, 2010
- New Analysis Assesses Impact of Common Genetic Variation on Benefit of Antiplatelet Therapy
- Inadequate Response to Clopidogrel Leads to Higher Incidence of Major Adverse Cardiac Events in Patients Who have Undergone PCI
March 20, 2010
- Study Shows Prevenar 13* Is Immunogenic In Young Children Previously Vaccinated With Prevenar*
- BioSense Technologies' Novel Diagnostic Testing Platform for Rapid Drug Susceptibility Presented at the National Foundation for Infectious Disease 2010 Annual Conference
March 21, 2010
- Phase 2 Data on Provectus's PV-10 To Be Presented at the 2010 ASCO Scientific Program on June 4 - 8 in Chicago
- Biovest Announces Upcoming Conference Calendar to Present on Personalized Cancer Vaccine Targeting B-cell Lymphomas
- Phase 3 Trial in NSCLC Meets Primary Endpoint; Abraxane compared to Taxol, both in combo with carboplatin
- Human Genome Sciences Announces Results of Randomized Phase 2 Trial of Mapatumumab in Non-Small Cell Lung Cancer
- Ovatech Reports Enrollment is Closed for Phase 2 Clinical Trial of Ovaprene Non-Hormonal Intravaginal Contraceptive Ring at New York Downtown Hospital (NYDH)
- Emerging Interventional Radiology Treatment With Drug-Eluting Stents Saves Limbs
March 22, 2010
- NicOx: Publication of naproxcinod phase 3 data in Osteoarthritis and Cartilage
- Abraxane Meets Primary Endpoint In Phase 3 Trial For Advanced Non-Small Cell Lung Cancer
- New PLATO Sub-Analysis of CABG Patients Presented at ACC
- Arrowhead Research Subsidiary, Calando Pharmaceuticals, Provides First Proof of RNA Interference in Humans with Systemically Administered siRNA Therapeutic; Clinical Trial Results Published in Nature
March 23, 2010
- BioSante Announces Additional Positive Leukemia Vaccine Results and Second FDA Orphan Drug Designation
- Dynavax Reports Positive Findings From Detailed Safety Analysis of HEPLISAV
- Advaxis Immunotherapeutic ADXS11-001 Phase 1 Survival Data Extended
- InNexus Bio DXL Antibody Technology Causes Cancer Cell Death By Mechanisms Not Seen with Current Market-Leading Medications
- Othera Pharmaceuticals Reports Preserved Visual Function in Clinical Trial of OT-551 Eye Drop Treatment for Advanced Dry AMD
March 24, 2010
- Acceleron and Collaborators Publish Two Papers on ACE-041, a Novel Angiogenesis Inhibitor, in Journal of Experimental Medicine and Molecular Cancer Therapeutics
- Human Genome Sciences Announces Interim Results of Phase 2b Monthly-Dosing Trial of ZALBIN in Patients with Chronic Hepatitis C
- Celera Publishes Data Extending the Association Between the KIF6 Gene Variant and Differential Reduction of Coronary Events From Statin Therapy to the Elderly With Prior Vascular Disease
- IN-STEP Phase IIb study results - V3381 misses primary endpoint in neuropathic pain
- PAREXEL Completes Early Phase Study Requiring Genotyping of More Than 10,000 Potential Participants
- NOVAVAX Announces Positive Clinical Results from First Stage of Pivotal Study of 2009 A/H1N1 VLP Pandemic Influenza Vaccine in Mexico
March 25, 2010
- Women Gather in Chicago at the Illinois Women's Conference March 25th!
- XIFAXAN 550 mg Tablets Demonstrate Significant Reduction of Risk for Episodes of Overt Hepatic Encephalopathy According to Findings Published in The New England Journal of Medicine
- Shire Presents Positive Data for Patients with Type 1 Gaucher Disease Who Switched to VPRIV
- Hatchtech Positive DeOvo Head Lice Phase Ii Clinical Trial Results
- Argos Therapeutics Presents New Phase 2a Data on the Impact of Arcelis HIV Program on Viral Genetic Diversity
- RXi Pharmaceuticals to Present New Preclinical Data Demonstrating the Robust Performance of its RNAi Therapeutics Platform
- Independent Studies Demonstrate that NellOne Therapeutics' Protein Has Potential to Heal Damaged Skeletal and Heart Muscle
- RXi Pharmaceuticals Presents Self-Delivering RNAi Data at Scar Club Meeting in France
- Catalent Formulation Expert To Present
- 2010 BIO International Convention to Feature Full Lineup of International Programming
- Jeff Kindler Added to World Innovation Forum Lineup
- Advaxis to Present at the 6th Annual Spring Growth Stock Conference
- NexMed, Inc. to Co-Sponsor Biotalk of Dr. Diego Miralles of Johnson & Johnson at the San Diego Biotechnology Discussion Group
- Society for Biomolecular Sciences to Hold Biopharmaceutical Symposium in San Francisco
- Nutra Pharma to Present and Exhibit at Upcoming Investment Conferences in Vancouver, Canada, and Las Vegas, Nevada
- WIN Symposium on Personalized Cancer Care Receives Endorsement from ASCO, ESMO and OECI
March 26, 2010
- Hepatitis C treatment less effective in urban minority patients
- Rapid Development Of Drug-Resistant 2009 H1n1 Influenza Reported In Two Cases
March 29, 2010
- Presidio Pharmaceuticals, Inc. to Present at the Canaccord Adams' Hepatitis C Conference
- ExonHit Presents New Data on its Alzheimer's Lead Candidate at the International Geneva/Springfield Symposium
- San Antonio Community to Gather April 1 at Westin La Cantera Resort to Help Leukemia Patients
- YM BioSciences Presents CYT387 Data at International Leukemia Conference
- Paired Drugs Kill Precancerous Colon Polyps, Spare Normal Tissue
- NOVAVAX Releases Final Results from its Trivalent Seasonal Influenza Vaccine Phase II Clinical Study in Healthy Adults
- Pearl Therapeutics Announces Positive Results From Phase 1 Trial of PT003, a Bronchodilator Combination Therapeutic for Chronic Obstructive Pulmonary Disease, and Initiation of Phase 2b Trial
- Ligand Presents First-in-Human Phase I Data on Lead SARM Molecule LGD-4033 at the International Congress of Endocrinology
- Two Kinds of Multiple Sclerosis, Two Different Responses to Beta-Interferon, Stanford Study Shows
- EBD Group, Eurasanté, and IDIS create new international pharma-tech transfer event ?Biofit'
- Columbia Business School to Host 6th Annual India Business Conference on April 2, 2010
March 30, 2010
- Clinical Data, Inc. Reports Results of Phase I Studies of Stedivaze Demonstrating Safety and Tolerability in Patients with Asthma and COPD
- Nuvon's John Zaleski Featured Speaker at First-Ever AMA and IEEE Joint Conference
- NeuroVive Pharmaceutical AB (SE) - NeuroVive successfully completes clinical trial with Cremophor-free cyclosporine I.V. formulation
- Biomarkers, Vaccines and Personalized Medicine Hot Topics at 2010 BIO International Convention
- Sentrx to Exhibit at 19th Annual Partnerships in Clinical Trials
- Advanced BioHealing to Participate in Panel Discussion at Inaugural Translational Regenerative Medicine Forum
- Affymax and Takeda to Present Hematide/peginesatide Phase 2 Data at the National Kidney Foundation 2010 Spring Meeting
- Switching to Once-Daily Victoza (Liraglutide [rDNA Origin] Injection) from Exenatide Further Improves Blood Sugar Control in Patients with Type 2 Diabetes
- Trius Announces Results From Phase 1 Clinical Trial of Intravenous Torezolid Phosphate
- Anadys Announces Two ANA598 Presentations to Be Made at the EASL Annual Meeting in April
