Clinical Trial News Archive
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January 2012
January 3
AVEO and Astellas Announce Tivozanib Successfully Demonstrated Progression-Free Survival Superiority over Sorafenib in Patients with Advanced Renal Cell Cancer in Phase 3 TIVO-1 Trial
Generex Subsidiary Antigen Express Provides Update on AE37 Cancer Vaccine's Clinical & Regulatory Strategy
Osiris Therapeutics Provides Update on Groundbreaking Stem Cell Trial for Type 1 Diabetes
Can-Fite BioPharma Announces Successful Results of its Phase I/II Liver Cancer Study with its CF102 Drug; the Study Achieved the Primary and Secondary Endpoints
January 4
OncoGenex Announces Publication of Phase I/II Custirsen (OGX-011/TV-1011) Data in Journal of Thoracic Oncology
Alnylam Reports Positive Preliminary Clinical Results for ALN-PCS, an RNAi Therapeutic Targeting PCSK9 for the Treatment of Severe Hypercholesterolemia
Despite International Concern, U-M Study Shows 2006 Re-introduction of Rotavirus Vaccine Not Linked to Increase in Intussusception
January 5
ProFibrix US Phase II Study with Fibrocaps Meets All Primary and Secondary Endpoints
Tetragenetics' G-SOME-Formulated Influenza Vaccine Provides Strong Protection Against H5N1 in Preclinical Efficacy Study
Major milestone achieved: the Phase IIa clinical trial in rheumatoid arthritis meets its endpoint
Goff Hill Ltd. Announces the Cure for Cancer and Viral Diseases
OrbusNeich's Genous Stent Achieves Good, Comparable Clinical Outcomes in Patients Discontinuing Dual Antiplatelet Therapy at 30 Days and at Six Months
Tekmira?s LNP Technology Enables Alnylam?s Positive ALN-PCS Clinical Data
RegeneRx Receives Clinical Study Report for Phase 2 Dry Eye Trial
DURECT Announces Top-line Data from BESST (POSIDUR) U.S. Pivotal Phase III Trial
January 6
January 9
January 10
Omthera Pharmaceuticals Announces Positive Long Term Bioavailability Data Comparing Epanova to Lovaza
Dabigatran Associated with Increased Risk of Acute Coronary Events
LX4211 Enhances Effects of DPP-4 Inhibition in Patients with Type 2 Diabetes
Techulon's Platform Demonstrates Effective Non-Viral DNA Delivery for in vivo Cardiac Study
Civitas Therapeutics Announces Positive Results from Clinical Study of CVT-301, an Inhaled L-dopa for Parkinson?s Disease
Achillion Reports Clinical Data on Portfolio of Protease Inhibitors
Gastrointestinal Cancers Symposium of the American Society of Clinical Oncology (ASCO-GI): Phase III Data on Bayer's Investigational Compound Regorafenib (BAY 73-4506) in Patients with Metastatic Colorectal Cancer to be Presented as Late Breaking Oral Presentation at 2012 ASCO-GI Congress
January 11
Vical Provides Updates on CMV Vaccine Programs
Spherix Announces Successful Completion of Important Toxicology Study of SPX-106
Potential Role of Natural Alkaloids in Combatting Memory Loss
Cannabis Science Reports Apparent Success For 3rd Self-Medicated Cancer Patient
Ember Therapeutics Announces Nature Publication of Brown Fat Biology Data; Program Exclusively Licensed from the Dana-Farber Cancer Institute
Research in Rare Genetic Disease Poised to Provide New Therapies, According to New White Paper from Tuberous Sclerosis Alliance
January 12
Synta Pharmaceuticals and University of Toronto Researchers Elucidate Elesclomol Mechanism of Action Using Innovative Yeast-based Technology
Researchers Find First Major Gene Mutation Associated With Hereditary Prostate Cancer Risk
Conventional Nerve Repair Wisdom Defied in First-Ever Multicenter Clinical Study with Processed, Donated Nerve Tissue
January 17
REVIVE Trial Results for Avanafil Published in JSM Demonstrate Significant Improvement in Erectile Function
"O-Shot" May Improve Female Sexual Response
Medivation and Pfizer Announce Results from Phase 3 Concert Trial of Dimebon in Alzheimer's Disease
Colby Pharmaceutical Company Announces Publication of JVRS-100 use as Potent Immune Activating Adjuvant in Combination with H5N1 Influenza Vaccine
ArQule Announces Tivantinib Meets Primary Endpoint, Significantly Extending Time to Progression in Phase 2 Trial in Second-Line Hepatocellular Carcinoma
Synta Announces Publication of Results Showing Ganetespib Synergizes with Taxanes in Multiple Non-small Cell Lung Cancer Models
First Preclinical Proof-of-Concept of Mutation-Based Individualized Cancer Vaccine
Pevion's Therapeutic Candida Vaccine Generates Functional B Cell Memory in all Vaccinees
BrainStorm Announces Clinical Data Supporting Safety and Efficacy of NurOwn Based on Initial Patient Results
Niiki Pharma Announces the Completion of Phase I Dose Escalation for First-in-Man Anti-Cancer Agent NKP-1339
PV-10 Mechanism of Action Data to Be Presented at the Society of Surgical Oncology Annual Meeting March 21-24, 2012 in Orlando, Florida
Scripps-led Study in JAMA Shows New Drug Helps "Bridge" Stent Patients to Cardiac Surgery
January 18
Drug Helps Maintain Platelet Inhibition and Anti-Clotting Levels Prior To Cardiac Surgery
PROLOR Biotech Announces Positive Top-Line Results From Pilot Study of Its Long-Acting Human Growth Hormone Injected Twice Per Month
InflaRx Announces Successful Conduct of Its Clinical Phase I Trial with IFX-1, a New Monoclonal Antibody Inhibiting Complement Driven Inflammation
Soligenix Demonstrates Robust Stability Results with its SGX204 Anthrax Vaccine
Prolor Biotech Announces Positive Top-Line Results From Pilot Study of Its Long-Acting Human Growth Hormone Injected Twice Per Month
January 19
OncoGenex Announces Presentation of OGX-427 Data at the ASCO 2012 Genitourinary Cancers Symposium
Researchers Uncover How New Melanoma Drug Accelerates Secondary Skin Cancers
Combination of Oral Drugs Suppresses Common Type of Hepatitis C, According to University of Michigan-led Research
Pregnant Women Who Develop Life-Threatening Blood Clots Should Receive Aggressive Treatment, Research At ISET 2012 Shows
Cannabis Science Updates Second Medical Cannabis Cancer Patient Suffering from Squamous Cell Carcinoma Photo-documents Cannabis Extracts Killing Cancerous Tumor
Phase III Data Show Bayer's Investigational Compound Regorafenib (BAY 73-4506) Met Primary Endpoint Showing Statistically Significant Improvement in Overall Survival in Patients with Metastatic Colorectal Cancer Refractory to Standard Approved Therapies
Drug Improves Survival of Colorectal Cancer Patients, Trial Results Show
January 20
January 23
VentiRx Pharmaceuticals Publishes Preclinical Data of Novel TLR8 Agonist, VTX-2337, Supporting Its Potential as an Immunotherapeutic Approach in Cancer
BioRestorative Therapies to Present at 7th International Conference on Cell Therapy for Cardiovascular Disease
Senior Management of NeoStem and Its Subsidiaries Invited to Speak at Seventh International Conference on Cell Therapy for Cardiovascular Disease
January 24
January 30
Juventas Therapeutics Reports One Year Data From Phase I Heart Failure Clinical Trial
Compugen Presents Three Product Candidates for Treatment of Autoimmune Diseases at the Immunotherapeutics & Immunomonitoring Conference
Infinity Reports Update from Phase 2 Study of Saridegib Plus Gemcitabine in Patients with Metastatic Pancreatic Cancer
Cannabis Science Presents Newest Photographs From 3rd Cancer Patient That Show Cancer Tumors Dying and Areas That Are Now Pain Free
Seattle Genetics and Millennium Report Data from Phase I Trial of ADCETRIS in Front-line Mature T-Cell Lymphomas
ImmunoCellular Therapeutics To Deliver Presentation on Cancer Stem Cells at Prestigious Immunotherapy Conference
Cardium Presents New Generx Findings at 2012 Annual Gene and Cell Therapy Forum
Synageva BioPharma Highlights Key Data Presentations at Upcoming Lysosomal Disease Network (LDN) World Symposium
Results of NoNO Inc.-Sponsored Phase 2 Clinical Trial in Procedurally-Induced Strokes to be Announced at the International Stroke Conference
VGX-100 Identified as Potential New Therapy for Improving Corneal Graft Survival
Inherited Risk Factors for Childhood Leukemia are More Common in Hispanic Patients
January 31
Exciting Data from Remedy Pharmaceutical-Sponsored Stroke Drug Trial to Be Presented at the 2012 International Stroke Conference in New Orleans
BioRestorative Therapies Signs License Agreement for Stem Cell Disc/Spine Procedure
Vical Presents Case Study on Successful Design of Allovectin Phase 3 Melanoma Trial
Inovio Pharmaceuticals Moves Closer to ?Universal? Influenza Vaccine By Demonstrating Protective Immune Responses against Multiple H3N2 and Type B Strains in Animal Studies
HTI-501 Data Support Commencement of Phase 2 Portion of Clinical Trial
Inovio Pharmaceuticals Moves Closer to "Universal" Influenza Vaccine by Demonstrating Protective Immune Responses Against Multiple H3N2 and Type B Strains in Animal Studies
Ampio Pharmaceuticals, Inc. Announces Statistically Significant Improvement in Pain Relief for its Lead Product, Ampion(TM) in the Osteoarthritis of the Knee Trial.
Argos Therapeutic Arcelis Immunotherapy AGS-003 in Combination With Sunitinib Shows Statistically Significant Correlation of Immune System Response to Overall Survival in Phase 2 Study in Patients with Advanced Renal Cell Carcinoma (RCC)
