Clinical Trial News Archive
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January 2009
January 5
Immutep Announces Positive Interim Results in Phase I/II Chemoimmunotherapy Trial in Breast Cancer
Merck Serono: Study Published in JCO Shows Erbitux Enhances Efficacy in mCRC Patients with KRAS Wild-Type Tumors in 1st-Line Setting
Discovery Labs' Surfaxin Phase 2 BPD Clinical Trial Results Published in Pediatrics
Genmab Announces Interim Results in Pivotal Study of Zalutumumab in Head and Neck Cancer
Inflammatory Factors May be Key to Controlling Diabetic Macular Edema
January 6
Kythera Biopharmaceuticals Announces Positive Results from Two Phase 2 Studies with ATX-101 Demonstrating Reduction of Submental Fat
Research Published in Nature Medicine Shows Disruption of Chemokine Interactions Inhibits Atherosclerosis in Mice
Acacia Pharma Completes Clinical Trial with APD 405 for Nausea & Vomiting
Study Demonstrates that AHCC Enhances Immune System by Increasing the Production of Key Dendritic Cells
January 8
ANA598 Demonstrates Potent Antiviral Activity in an Early Clinical Study in HCV-Infected Patients
Positive Results for Peplin's Phase IIb AK Trial
Syntarga Demonstrates In Vivo Proof of Concept for its Antibody-Drug Conjugate Technology
First Candidate from Scynexis' Novel Cyclophilin Inhibitor Platform, SCY-635, Establishes Proof of Concept in HCV-Infected Adults
Juvaris BioTherapeutics Announces Positive Data from Clinical Trial of JVRS-100 Adjuvanted Flu Vaccine
Altus Pharmaceuticals Successfully Completes Phase 1 Study of Long Acting Formulation of Recombinant Human Growth Hormone
Why Bladder Cancer Is Deadlier for Some
January 9
Study Finds More Effective Treatment for Pneumonia Following Influenza
Orexigen Therapeutics Announces First of Four Phase 3 Trials of Contrave Meets Co-Primary and Key Secondary Endpoints
RegeneRx Reports Phase II Pressure Ulcer Trial Results
Gene Abnormality Found to Predict Childhood Leukemia Relapse
New Malaria Drug May Meet Resistance Says Expert
January 12
ARYx Therapeutics, Inc. Provides Additional Data on Atrial Fibrillation Clinical Trial on ATI-2042
InterMune Reports Results from Triple Combination Study of ITMN-191
Repros Therapeutics Inc. Announces That Proellex Significantly Reduced Pain in a U.S. Phase 2 Clinical Trial in Women with Moderate to Severe Endometriosis
Qnexa Treatment Results in Improved Glucose Control in Obese Non-Diabetic Subjects
Sunesis Pharmaceuticals Provides Year-End Clinical Update on Voreloxin
InterMune to Conduct Conference Call and Webcast to Discuss Results of Triple Combination Study of ITMN-191
Seventeen Months After Cord Blood Transplant - Child is Free of Signs of Cancer
January 13
Data Published in Nature Cell Biology Reveal Novel Function of Drug Target EpCAM in Cancer Cell Signalling
Hana Biosciences Phase 1 Data On Menadione, Its Novel First-in-Class Compound for Treatment-Limiting Skin Toxicity Associated With EGFR Inhibitors, to be Presented At 33rd Hawaii Dermatology Seminar
Intra-Cellular Therapies Announces Successful Outcome of a Phase II Clinical Trial with ITI-007 in Patients with Sleep Maintenance Insomnia
NeurogesX Announces Publication of Phase 3 Data for QUTENZA (NGX-4010) in Postherpetic Neuralgia (PHN) by The Lancet Neurology
AcelRx Pharmaceuticals Reports Positive Results from a Clinical Trial of Sublingual Sufentanil/Triazolam NanoTab Combination (ARX-03) in Treating Procedural Pain and Anxiety
InNexus Biotechnology Completes Preclinical Study Confirming in Vivo Effectiveness and Safety of Lead Candidate DXL625, Schedules Meeting With FDA
Cytos Biotechnology Presents Analysis of Patient Diaries Including Six Month Follow-up Data from Phase II Study with CYT003-QbG10 Monotherapy for the Treatment of Allergic Diseases
Nymox Releases Positive New Clinical Trial Data on Durability of Response Rates to Company’s BPH Drug NX-1207
Suven Participates at Biotech Showcase 2009
January 14
New Overall Survival Study Results Confirm Oral Xeloda plus Oxaliplatin (XELOX) is Comparable to FOLFOX-4 for the First-Line Treatment of Advanced Colorectal Cancer
RAD001 Phase II Trial Results Positive in Patients with Advanced Gastric Cancer After Failure of One or More Prior Treatments
New Study First to Confirm Sandostatin LAR Depot Controls Tumor Growth in Patients With Rare Gastrointestinal Tumors
Algeta Completes Comprehensive Phase II Clinical Program With Alpharadin for Treating Bone Metastases in Patients With Advanced Prostate Cancer
Merck KGaA: New Data Reinforce Consistent Efficacy Profile of Erbitux in First-Line mCRC Patients with KRAS Wild-Type Tumors
Afinitor Phase II trial results positive in patients with advanced gastric cancer after failure of one or more prior treatments
Poniard Pharmaceuticals Announces Positive Tumor Response and Neuropathy Data from Phase 2 Clinical Trial of Picoplatin in Metastatic Colorectal Cancer
Mologen AG Announces Successful Course of Study of Cancer Drug MGN1703
Half of Adults 50 and Younger With Low 10-Year Risk of CVD Have High Lifetime Risk
January 15
Modigene Announces Positive Results of Pilot Toxicity Study of Its Long-Acting Human Growth Hormone hGH-CTP
Pegasys Proven Effective as Hepatitis C Treatment for Latino Patients, According to Article in The New England Journal of Medicine
New Tool Could Prevent Needless Stents and Save Money, Stanford Cardiologist Says
Study Shows How Defective DNA Repair Triggers Two Neurological Diseases
Neurotune Successfully Completes Phase 1 Trials with its Lead Compound NT-11624
A Study In This Month's Journal Of Nervous And Mental Disease Reveals Hope For Recovery From Suicidal Thinking And Treatment Resistant Mental Illness
January 16
January 20
Rexin-G Shrinks Metastatic Tumors and Triples Survival Time in Chemotherapy-Resistant Pancreatic Cancer: Analysis of a U.S. Phase I/II Clinical Trial
Immunomedics Announces Preclinical Therapy Results of SN-38 Immunoconjugate for Colorectal Cancer
Unigene Reports Positive Results on a Novel Peptide for Reducing Food Consumption
Chemoembolization Improving as Liver Cancer Treatment
January 21
Aradigm Reports Positive Phase 2 Results with Inhaled Liposomal Ciprofloxacin Hydrochloride in Patients with Bronchiectasis
Acusphere Announces Publication of Imagify Phase 3 Trials in the European Journal of Echocardiography
Clinuvel: Positive Interim Phase III Results Announced for Unique Skin Protection Drug
Cardiovascular Side Effects of Pioglitazone and Rosiglitazone Linked to Vascular and Energy Pathways by Genomas Clinical Study
Measurement of Kidney Function in Children with Kidney Disease Improved
Alnylam and Collaborators at Harvard Medical School Demonstrate In Vivo Silencing of Key Genes Implicated in the Transmission of Herpes Simplex Virus-2 (HSV-2)
January 22
ISTA Pharmaceuticals Announces Positive Results for Phase IIb Study of Ecabet Sodium
Zevalin Produced 83 Percent Complete Response Rate in Mucosa-Associated Lymphoid Tissue (MALT) Orbital Lymphoma Study
DiaKine Therapeutics Drug Improves Type 2 Insulin Action; Reduces Harm of Fat in Preclinical Study
Genaera Presents Promising Preclinical Data for Trodusquemine (MSI-1436) at Keystone Symposia
Interleukin Genetics to Present Data Highlighting Link Between Inflammatory Gene Variations and Less Effective Weightloss
New Clinical Equation Accurately Measures Kidney Function in Children
January 23
Hollis-Eden Researchers Present New Findings on Mechanism of Action for Anti-Cancer Drug Candidate Apoptone (HE3235)
Oral Investigational Treatment Cladribine Tablets for Multiple Sclerosis Significantly Reduced Relapse Rate in Phase III Pivotal Trial
Promedior's Fibrosis Program Featured at Keystone Symposia Conference
VIRxSYS to Present at Phacilitate Cell & Gene Therapy Forum
Onconova and DoD Collaborators Publish Research Demonstrating Increased Survivability of Previously Lethal Radiation in Mice with New Radioprotective Drug Ex-RAD
Cordex Pharma Presents 'New Frontiers in Cardiovascular Medicines' on January 29
Novavax CMO to Present at Phacilitate Vaccine Forum Washington 2009
January 26
University of California San Diego Researchers Present Preclinical Data Demonstrating Benefits of Triolex (HE3286) in Model of Obesity Induced Metabolic Disorders
Access Pharmaceuticals Presents New Combination Data on the Company's Angiolix Therapeutic Monoclonal Antibody
Rib-X Pharmaceuticals Announces Positive Phase 2 Study Results for Delafloxacin and a $25 Million Financing
January 27
Circulation Publishes Pivotal Two-Year Results On Xience V Drug Eluting Stent
Epilepsia Study Demonstrates New Add-on Antiepileptic Drug Vimpat Significantly Reduces Partial-Onset Seizures in Adults With Epilepsy
EpiCept Announces Positive Results from Phase IIb Trial for EpiCept NP-1
New Research Suggests Platelet 'Stickiness' May be the Single Most Important Risk Factor in Patients Treated with Coronary Stents - Findings May be Applicable to Anyone with Vascular Disease
January 28
Pixantrone Increases Progression-Free Survival by 81% Compared to Standard Chemotherapeutic Agents in Phase III Trial
St. Jude Finds More Than 100 Gene Variations Linked With Response to Leukemia Treatment
Sociability Traced to Particular Region of Brain by Stanford Scientists
PolyMedix to Present at Keystone Symposia Global Health Series Tuberculosis Biology, Pathology and Therapy
Addex Successfully Completes ADX48621 Phase I Program
AMT: Glybera Lowers Pancreatitis Incidence Significantly
Support Cells, Not Neurons, Lull the Brain to Sleep
January 29
New England Journal of Medicine Publishes Case Reports on the Investigational Use of Soliris (eculizumab) in Patients with Atypical Hemolytic Uremic Syndrome (aHUS)
Data from Columbia Laboratories' Study for the Prevention of Preterm Birth to be Presented at the Society for Maternal-Fetal Medicine (SMFM) 2009 Annual Meeting
CombinatoRx Publishes Data on Selective Amplification of Synergistic Combination Drug Candidate
Study Shows No Standardized Approach to Epidural Steroid Injections for Back Pain
Study Shows Leconotide, an Investigative Calcium Channel Blocker, Has Potential as a Selective, Efficacious, Non-Opioid Pain Treatment
Study of Cannabinoid Medicine for Pain Found Patients Got 'High,' but Effects Not Related to Pain Relief
January 30
BioMS Medical reports results of exploratory phase II trial of dirucotide in relapsing remitting multiple sclerosis
Cymbalta Significantly Reduced Osteoarthritis Knee Pain in New Study
ImmuPharma PLC Lupuzor Phase IIb study
King Pharmaceuticals Announces Positive Results from a 12-Month Open-Label Safety and Efficacy Study of Embeda Extended Release Capsules
Effectiveness of Progesterone in Reducing Preterm Births May Be Altered by Genetic Predisposition
Under-Treatment of Pain Exacerbated by Public Perceptions of Medicines and Safety
Journal Article Reviews Research Using Oxycyte and PFCs in TBI and Decompression Sickness
Cook Medical Unveils the Advance Drug-Eluting Balloon and Other Cutting-Edge Devices to Advance Leg Therapy
