Home › News › Clinical Trials › Archive

Clinical Trial News Archive

Get news By email or subscribe to our News feeds.

All News Consumer Pharma New Drugs Pipeline Clinical Trials

February 2008

February 1

The LANCET Published ENDORSE, the Largest Multinational Study Showing That the Majority of Hospitalized Patients Surveyed are at Risk for VTE and Many do not Receive Recommended VTE Prophylaxis Pooled Phase 3 Study of Nplate (Romiplostim) in Adult Patients with Chronic ITP Published in The Lancet New Findings Show Enbrel (etanercept) Significantly Reduced Levels of C-Reactive Protein, a Marker of Inflammation, in Patients with Moderate to Severe Plaque Psoriasis MediciNova's MN-166 Reduces Persistent Black Hole Formation in Multiple Sclerosis Patients Obagi Medical Products' Solubilized Benzoyl Peroxide Provides Clinically Significant Lesion Reduction for Mild to Moderately Severe Acne Data Demonstrate that Obagi Medical Products' Condition & Enhance Skin Care System is an Effective Complement to Facial Rejuvenation Procedures Researchers Find Biological Factors That May Drive Prostate Tumor Aggressiveness in African-American Men Analytical Results for Women from Large Scale Clinical Trial MEGA Study Employing the Hypercholesterolemia Drug Mevalotin® Published New Data for Achillion's Elvucitabine Demonstrate Drug's Safety, Efficacy and Suitability for Combination Therapy in HIV-Infected Patients Prostate Cancer: Watchful Wait or Vaccinate? NexMed Announces Presentation of Data at the 66th Annual Meeting of the American Academy of Dermatology Observational Data Show Transfusion Patterns in Chemotherapy-Induced Anemia Patients Receiving Erythropoiesis-Stimulating Agents Neuro-Hitech Reports Cognitive Improvement From Phase Two Clinical Trial of Huperzine A In Alzheimer's Disease Patients Heart Disease Deaths Continue to Decline in American Women Remicade-Treated Patients Experienced Rapid and Substantial Improvement in Psoriasis in Critical Regions of Body

February 4

Clinical Data Reported on Celgene Compound Apremilast (CC-10004) Evaluating Efficacy, Safety and Quality of Life Improvement for Psoriasis Patients NanoBio Corporation Presents Preclinical and Interim Clinical Data on Topical Treatments for Herpes Labialis and Onychomycosis at AAD 2008 IDM Pharma Announces Phase 3 Mifamurtide (L-MTP-PE) Study Demonstrating Improved Survival Published in the Journal of Clinical Oncology BioLineRx Announces Positive Results From Phase 2a Trial of BL-1020, a GABA-Enhanced Antipsychotic for the Treatment of Schizophrenia Oncolytics Biotech Inc. Announces Publication of Research on Combination Reovirus and Radiation Therapy ReachMD Broadcasts First-of-its-Kind Physician Peer-Peer Discussion on ENHANCE Trial Ustekinumab (CNTO 1275) Phase 3 Data Show Long-Term Improvement Of Chronic Plaque Psoriasis Study Suggests Risperidone Long-Acting Injection Combined with Standard Treatment Helped Delay Time to Relapse in Patients with Bipolar Disorder Oncolytics Biotech Inc. Announces Publication of Research on Combination Reovirus and Radiation Therapy Penwest Announces Results of Phase IIa Clinical Study of Nalbuphine ER PhytoMedical Bolsters Cancer Research Following Favorable Results St. Jude Finds Risk Factors for Severe RSV Infection in Immunocompromised Children

February 5

Forest Laboratories, Inc. Announces Positive Results of Memantine Study of Once-Daily Formulation PTC Therapeutics Announces Publication of Preclinical Data in PNAS Savient Reports Additional Positive Trial Data for Secondary Endpoints from Puricase (pegloticase) Phase 3 Studies ATryn(R) Meets Primary Endpoint Hollis-Eden Pharmaceuticals Presents Additional Data Demonstrating Activity of Apoptone in Inducing Cancer Cell Death Ceremed's Ostene Stops Bone Bleeding Without Added Risk of Surgical Infection, New Study Finds Avanir Announces Progress on Zenvia Development Cleviprex Demonstrated Rapid, Precise Blood Pressure Control in High-Risk Patients, According to New Analyses Multiple Dose Clinical Trial of TorreyPines Therapeutics' Tezampanel Demonstrates Compound is Safe and Well-Tolerated Novel Small Molecule Therapy Shows Benefit for Anemic Patients Via Hydration of Red Blood Cells John Wayne Cancer Institute Researchers Show that a Key Protein Appears to Enable Spread of Melanoma to the Small Intestine

February 6

Artes Medical's 5-Year Safety and Efficacy Data Presented at the American Academy of Dermatology Conference Senesco Technologies Reports on Results of Preclinical Multiple Myeloma Studies Biovitrum and Symphogen have Successfully Completed Phase I Clinical Trial with Recombinant Polyclonal Antibody Lotus Pharmaceuticals, Inc. Achieves Significant Milestones in the Development of Isosorbide Mononitrate Sustained Release Tablets VIR201 Phase IIa Trial Results Now Published in Peer Reviewed Scientific Journal – Human Vaccines Leading Investigators Highlight Advances in Photodynamic Therapy at the American Academy of Dermatology Annual Meeting Nymox Announces Positive Results from New Multi-Center U.S. Study of NX-1207 For BPH Intercell’s Therapeutic Hepatitis C Vaccine Meets Primary Endpoints in Phase II Molecular Therapy Succeeds in Preventing Craniofacial Birth Defect in Mice Dr. Neil Sadick Presents on Pyratine-6 at the Annual Meeting of the American Academy of Dermatology

February 7

EpiCept Announces Encouraging Results of Phase II Trial for NP-1 Cream in Diabetic Peripheral Neuropathy Genes as Time Machines Data From Anthera's Plasma Trial to be Presented as Late Breaker at American College Of Cardiology Scientific Sessions ADVENTRX to Present Complete ANX-530 Pharmacokinetic Data at the 2008 American Association for Cancer Research Annual Meeting IDX899 Demonstrates Rapid and Profound Inhibition of HIV Replication in a Phase I/II Clinical Trial in Treatment-Naive HIV-Infected Patients Pfizer Presents New Data from HIV/AIDS Portfolio at Conference on Retroviruses and Opportunistic Infections Merck's Isentress (raltegravir) Tablets in Combination with other Anti-HIV Medicines Maintained Reductions in HIV-1 Viral Load and Increased CD4 Cell Counts Through 48 Weeks of Therapy in Treatment-Experienced Adults CASTLE Study Showed Similar Efficacy Between Once-Daily Reyataz (atazanavir sulfate)/ritonavir and Twice-Daily lopinavir/ritonavir at 48 Weeks in Previously Untreated HIV-Infected Adult Patients Vicriviroc Demonstrates Potent and Sustained Viral Suppression Through 48 Weeks of Therapy in Treatment-Experienced HIV-Infected Patients VIRxSYS Announces Interim Results from VRX496 Gene Therapy Phase II Trial Theratechnologies Presents Additional Results from Its Tesamorelin 52-week Phase 3 study at the Conference on Retroviruses and Opportunistic Infections Bevirimat Data Presented at 15th Conference on Retroviruses and Opportunistic Infections EpiCept Announces Encouraging Results of Phase II Trial for NP-1 Cream in Diabetic Peripheral Neuropathy Roche and Pharmasset To Present the R7128 Monotherapy Resistance Profile Ardea Biosciences Presents Preclinical Data Demonstrating Favorable Resistance Profiles for Non-Nucleoside Reverse Transcriptase Inhibitors for the Treatment of Human Immunodeficiency Virus New 48-Week Efficacy and Safety Data Presented for Intelence (etravirine) as Part of HIV Combination Therapy GeoVax Labs, Inc.'s Promising HIV/AIDS Vaccine Trial Data Presented at Retrovirus Conference Novelos Therapeutics and MUSC Abstract Accepted for Presentation at 2008 AACR Annual Meeting DNA Predicts Reaction to Drug That Fights Alcohol Dependence Amdoxovir plus Zidovudine Demonstrates Potent Antiviral Activity in HIV-Infected Patients Positive Results from Phase III Trial of Gamunex in Patients with CIDP QSB Anti-Virulence Platform Inhibits Biofilm Formation by Staphylococcus Aureus MRSA and Candida sp Sustained High Efficacy of Gardasil Against Precancerous Cervical Lesions Confirmed in Longest Follow-up of Large Phase III Studies Inhibitex HIV Integrase Inhibitor Data Presented at 15th Annual Conference on Retroviruses and Opportunistic Infections Alnylam Reports Pre-clinical Progress with RNAi Therapeutics in Neurological Disease Physicians Reconsider Implications of Enhance Trial

February 8

Labopharm Reports Positive Results for Phase III Study on Once-daily Trazodone American Heart Association Themed Issue Journal Report: Journal Edition Dedicated to Women's Unique Hypertension Issues InNexus Biotechnology Announces Preliminary Results of Animal Study Comparing Cancer Killing Activity of Its DXL625 (CD20) Treatment for Non-Hodgkin's Lymphoma With Leading Marketed Product Aprotinin and Ace Inhibitors During Off-Pump Cardiac Surgery Associated with Postoperative Renal Dysfunction Human Activity and Climate Change Could Aid Spread of Flaviviruses Discovery of New Gene Locus Associated with LDL-cholesterol Levels Could Lead to New Treatments Clinical Experience With Peregrine's Anti-Cancer Agent Bavituximab Presented at Leading Symposium on Anti-Angiogenic Agents InNexus Biotechnology Inc. To Host A Webcast Teleconference Detailing Recent News on Royalty Pharma Agreement & Preliminary Results of DXL625 Animal Study Gene Variant Predicts Medication Response in Patients with Alcohol Dependence

February 11

New Data Shows Davanat Extends Survival of End-Stage Colorectal Cancer Patients More Than 6 Months BioDelivery Sciences to Present BEMA Fentanyl Data at the 24th Annual Meeting of the American Academy of Pain Medicine Genetic Immunity Presents Clinical Data on DermaVir Patch Immune Therapy at 15th Annual Conference on Retroviruses and Opportunistic Infections Bentley Pharmaceuticals Announces Completion of Treatment in Phase II India Clinical Study in Type 2 Diabetes and Preliminary Clinical Results Pharmacyclics Announces Data and Publication Characterizing Highly-Selective HDAC Inhibitor Pixantrone Shows Activity in a Preclinical Study of Experimental Autoimmune Myasthenia Gravis (EAMG) Clavis Pharma Successfully Completes Clinical Phase I Study in Haematology Novel anti-CD20 monoclonal antibody ofatumumab demonstrates anti-tumour responses in patients with relapsed/refractory B-cell chronic lymphocytic leukaemia Advanced Cell Technology Announces Presentation of Results from Myoblast Study at ISCTR World Symposium AGI Dermatics Data Indicates 8 Oxo-Guanine Repair Enzyme OGG1 Encapsulated in Liposomes, Reduces MMP-1, Increases Collagen and Enhances DNA Repair AGI Dermatics Clinical Data Identifies L-Ergothioneine as Part of Skin's Natural Antioxidant System AGI Dermatics Clinical Data Indicate Bicyclic Monoterpene Diols Suppress MMP1 and Stimulate Collagen Through TNF-a Signaling

February 12

Compugen Announces In-Vivo Results for Two Novel Peptide Agonists of MAS GPCR for Potential Treatment of Cardiovascular Pathologies Micromet Announces the Publication of BiTE Antibody Review in Drugs of the Future Raven biotechnologies to Provide Updates on Oncology Pipeline With Four AACR Presentations Biovitrum has Completed an Exploratory Clinical Phase II Study in Glaucoma Ipsen: Clinical Update For Decapeptyl 6-Month Formulation in Advanced Prostate Cancer New Survey Shows African-Americans Are Concerned With Heart Health but Unaware of Link to Brain Health Hana Biosciences Announces Top-Line Phase 1 Clinical Trial Data Demonstrating Alocrest to be Well-Tolerated With Promising Anti-Tumor Activity Depomed Reports Positive Efficacy Data From a Phase 2 Trial of Gabapentin GR in the Treatment of Menopausal Hot Flashes Valeant Pharmaceuticals Reports Positive Phase III Results for Retigabine in RESTORE 1 Iomai Study Shows Self-Applied Travelers' Diarrhea Vaccine Patch Comparable to Clinician-Applied Vaccine Patch 2008 is a Decisive Year for the Validation of the Asthma Target Interleukin-13 Patch Instead of Pills Makes Living with Alzheimer's Disease Easier

February 13

ARIUS Presents New Findings Showing Therapeutic Antibody Inhibits Human Leukemic Cancer Stem Cells DOR BioPharma Announces Positive New Pulmonary Effect Data from orBec Clinical Trials Cytheris Announces 48-Week Results of Phase I/II Study Showing Administration of Interleukin-7 (IL-7) Significantly Improves CD4 T-Cell Counts in Chronically Infected HIV-1 Patients Avado Study of Avastin Plus Docetaxel Chemotherapy Showed Improved Progression-Free Survival in Patients With Advanced Breast Cancer AVADO Study of Avastin Plus Docetaxel Chemotherapy Showed Improved Progression-Free Survival in Patients with Advanced Breast Cancer Preliminary PI-88 Phase 2 Prostate Cancer Results to be Presented at the American Society for Clinical Oncology (ASCO) 2008 Genitourinary Cancer Symposium Protox to Present Prostate Cancer Data at ASCO Conference VEGF Neutralization Can Damage Brain Vessels, Say Schepens Eye Research Institute Scientists Preliminary PI-88 Phase 2 Prostate Cancer Results to be Presented at the American Society for Clinical Oncology (ASCO) 2008 Genitourinary Cancer Symposium Cytheris Announces 48-Week Results of Phase I/II Study Showing Administration of Interleukin-7 (IL-7) Significantly Improves CD4 T-Cell Counts in Chronically Infected HIV-1 Patients Publication of Data Concerning CAVATAK in Breast Cancer Unique Treatment for Alzheimer's Disease Improves Behavioural Symptoms for Patients - Ebixa Can Provide Benefits Alone or in Combination Marshfield Clinic Discovers Gene Variant Which Will Significantly Enhance the Accuracy of Molecular Tests for Warfarin Metabolism

February 15

Intra-Cellular Therapies Presents Data on Its Schizophrenia and Cognition in Schizophrenia Programs at the 14th Biennial Winter Workshop on Schizophrenia and Bipolar Disorders Medical Therapies Limited Announce Positive Interim Results From Cuprindo Phase I Clinical Trials Poniard Pharmaceuticals Announces Positive First-line Phase 1 Safety and Efficacy Data With Picoplatin in Metastatic Prostate Cancer Patients OncoGenex Reports Lead Drug Candidate OGX-011 Achieved Primary Endpoint in Phase 2 Trial with Second-Line Chemotherapy for Prostate Cancer Cell Genesys Reports Association Between Immune Response and Patient Survival in Phase 2 Trial of GVAX Immunotherapy for Prostate Cancer Medical Therapies Limited (ASX:MTY) Announce Positive Interim Results From Cuprindo Phase I Clinical Trials Oncoproteins Double-Team and Destroy Vital Tumor-Suppressor Novel Approach Strips Staph of Virulence Higher Body Mass Index Means Higher Risk of Several Cancers Cougar Biotechnology Announces Presentation of Positive CB7630 Phase I Clinical Data at ASCO 2008 Genitourinary Cancers Symposium

February 19

Bayer and Onyx Provide Update on Phase 3 Trial of Nexavar in Patients With Non-Small Cell Lung Cancer Nanoviricides Found Highly Effective Against Ebola by USAMRIID Advanced Life Sciences Announces Successful Thorough QT Study of Cethromycin Drug Reduces Airway Mucus in Preclinical Asthma Model Plexxikon Announces Publication of Key Data Demonstrating Possible Personalized Medicine for a Variety of Cancers Callisto Announces Guanilib Presentation at the 5th Annual Meeting of Cancer Drugs Research and Development InNexus Biotechnology Announces Second Preclinical CandidateDXL702 (HER2/neu) Targeting Breast Cancer Can-Fite Initiated Phase I Clinical Trial With CF102 First Cohort Was Successfully Completed JADO Reports Clinical Proof of Concept With Raft Modulator in Atopic Dermatitis Giaconda - Clinical Phase Pilot Study Results

February 20

Antigenics Announces Publication of Phase 3 Melanoma Study Results in Journal of Clinical Oncology Phase I and Phase I/II DCVax-Brain Data Continues to Show Significantly Improved Survival Rates for Brain Cancer Patients Plexxikon Announces Publication of Key Data Demonstrating Possible Personalized Medicine for a Variety of Cancers Acrux Reports Compelling Results of Market Research on Testosterone MD-Lotion Sirtris Pharmaceuticals Co-Founder Presents First In-Vivo, Preclinical Data Showing SIRT1 Activation Can Suppress Tumor Formation and Growth Smoking's Effects on Genes May Play a Role in Lung Cancer Development and Survival Bausch & Lomb Announces Positive Clinical Results for Zylet in a Comparison of Safety and Efficacy with Tobradex in the Treatment of Blepharokeratoconjunctivitis Stress Hormone Impacts Memory, Learning in Diabetic Rodents Nymox's NX-1207 Offers a New and Attractive Approach to the Treatment of Benign Prostatic Hyperplasia Novocell Reports Successful Use of Stem Cells to Generate Insulin in Mice

February 25

Top-Line Results From Pivotal Phase 3 MEND-CABG II Clinical Ipsen: Toremifene Citrate 80 mg Meets Primary and Key Secondary Endpoints in Phase III Clinical Trial in Advanced Prostate Cancer Patients on Androgen Deprivation Therapy CV Therapeutics Announces Presentations at the American College of Cardiology 57th Annual Scientific Session MacuSight Announces Positive Preliminary Results From Phase 1 Study of Sirolimus in Wet Age-Related Macular Degeneration Orion OYJ: GTx Announced Phase III Clinical Data for Toremifene Citrate 80 mg GTx's Toremifene Citrate 80 mg Meets Primary and Key Endpoints in Phase III Trial in Advanced Prostate Cancer Patients on Androgen Deprivation Therapy Publication of Data concerning Cavatak and Evatak in Prostate Cancer Elixir Pharmaceuticals Presents New Data on Ghrelin Inhibition at Keystone Meeting NexGenix Pharmaceuticals Presents Data on a Novel Small Molecule Inhibitor of Heat Shock Protein 90 (Hsp90) at the GTCbio Cancer Drugs Research & Development Conference Idenix Announces Data Presentations at the 43rd Annual Meeting of the European Association for the Study of the Liver (EASL) ISTA Pharmaceuticals Announces Physician-Sponsored Clinical Study of Xibrom Combination Therapy with Lucentis Oncothyreon's PX-478 is Effective in Preclinical Model of Human Lung Cancer

February 26

ARIUS Announces Five Abstracts Selected for Presentation at 2008 AACR Annual Meeting Bradmer Announces Phase II Results Published in Newly Diagnosed Glioblastoma which Demonstrate Improved Survival and Support Upcoming Phase III Study Lux Biosciences to Provide Update on Four Pipeline Programs, Including Two Phase 3 Clinical Programs, at ARVO Prana Announces Success in Phase IIa Clinical Trial of PBT2 in Early Alzheimer's Oral Talactoferrin Alfa Improves Overall Survival in Patients With Refractory Non-Small Cell Lung Cancer: Final Phase 2 Study Results Presented at the 8th Annual Targeted Therapies for the Treatment Of Lung Cancer Meeting Eurand Announces Positive Pharmacokinetic Study Results of Once-a-Day Ondansetron Lixte Biotechnology Holdings, Inc. Announces Further Developments Regarding the Anti-Cancer Activity of Its Patent-Pending Proprietary Compounds Data on PolyMedix Antimicrobial Polymers Presented at American Society of Microbiology 6th Annual Biodefense and Emerging Diseases Research Meeting PrimeGen Biotech Announces Non-Viral Reprogramming of Human Cells into Stem Cells Pyratine-6 Study Published in Journal of Drugs in Dermatology Faster Chemo Technique Increases Survival in Children with Neuroblastoma Nasal Vaccine for Smallpox Confers High Levels of Immunity Without Safety Risks Immunosyn Releases Wound Healing Photographs From the First Phase 'Proof of Concept Trial' in Europe for Treatment of Diabetic Ulcers With Biopharmeceutical SF-1019

February 28

XenoPort and GlaxoSmithKline Report Positive Top-Line Results of Final Pivotal Trial of XP13512/GSK1838262 for Restless Legs Syndrome NeurogesX Announces Preliminary Results from Second Phase 3 Clinical Trial in HIV-DSP Athersys Announces Summary Results for Phase 1 Safety Study of Its Novel Obesity Drug Dr. Gabriel Sosne to Present New TB4 Anti-Inflammation Data at ARVO Everolimus (RAD001) Significantly Extends Progression-Free Survival in Advanced Kidney Cancer Patients After Failure of Other Targeted Therapy PAION's Anticoagulant Solulin Successfully Tested in First-in-man Study Intravenous Immunoglobulin Treatment is Associated with a Reduced Risk of Developing Alzheimer's Disease and Related Disorders Biothera Drug Synergistic with Avastin Against Cancer, Study Finds NeoStem Reports Positive Stem Cell Industry Research Trends From The Journal of the American Medical Association and Third Annual Stem Cell Summit

Clinical Trial Results Archive

2005

April

More News Resources

(web6)