Home › News › Clinical Trials › Archive

Clinical Trial News Archive

Get news By email or subscribe to our News feeds.

All News Consumer Pharma New Drugs Pipeline Clinical Trials

April 2008

April 1

DiObex Announces Presentation of Scientific Poster at Annual Meeting of American Society for Clinical Pharmacology and Therapeutics Elixir Medical Announces Positive Nine-Month Results From the Excella Novolimus-Eluting Coronary Stent System First-In-Man Study Phase III Studies of Investigational Trilipix (SLV348/ABT-335), In Combination with Statins, Meets Primary Endpoints on Improving LDL, triglycerides and HDL Cure HIV Reaches Out to Foundation Community to Fund LiSAVIOR InterMune Announces Top-Line Results of Phase 1b Trial of ITMN-191 (R7227) and Provides Program Update Sirtris Pharmaceuticals Presents at American Chemical Society April 7 AVANT's Single-Dose Oral Ty800 Vaccine Meets Primary Endpoints in Phase 2 Study New Data Showed Actos (pioglitazone HCl) Prevented Progression of Atherosclerotic Plaque Volume in Patients with Type 2 Diabetes ChemGenex Investigators Present Data on Clinical Activity of Omacetaxine in Imatinib-Resistant Chronic Myeloid Leukemia Patients With the T315I Mutation at International Leukemia Conference Bionovo Announces Publication of the Paper Detailing the Mechanism of Action of Its Cancer Drug BZL101 First Statin Monotherapy to Achieve Regression of Coronary Atherosclerosis by Angiography in a Major Clinical Study Study Confirms Anti-Infective ARIKACE Effectively Penetrates Mucus and Biofilm, and Kills Pseudomonas, a Bacteria Plaguing Cystic Fibrosis Patients Significant Reductions in Mortality and Cardiovascular Events Shown Using Blood Pressure-Lowering Treatment in Those Aged 80 and Over SurModics Announces First Human Use of SynBiosys Biodegradable Polymer on CardioMind Drug-Eluting Stent New Data Shows Ranexa Increases Glucose-Stimulated Insulin Secretion Final Data From the SEISMIC Trial Suggest Safety, Efficacy of Autologous Stem- Cell Therapy for Treating Congestive Heart Failure Merck's Investigational Rolofylline Associated with Improved Dyspnea and Preserved Renal Function in Acute Heart Failure Patients in a Phase III Pilot Study Lipitor Provided an Unexpectedly Potent Heart Benefit in Patients with Chronic Stable Angina, According to New Study TRITON Stent Analysis Data Presented at ACC. Eli Lilly and Company and Daiichi Sankyo Company, Limited; MS&L Trial starts of new modality of treating lung infections in Cystic Fibrosis patients Taxus Stent Demonstrates Similar Outcomes in Diabetic Patients Compared to Non-diabetics in Pooled Analysis of TAXUS IV and V Trials Study Finds Taxus Drug-Eluting Stent Beneficial in Treatment of Large Vessels Nymox Releases Positive New Clinical Trial Data on Response Rates to Company's Prostate Drug NX-1207 SPP100 (tekturna/rasilez) Reduces Left Ventricular Hypertrophy Latest Advances in Diabetes Research to be Presented in San Francisco, California at World's Largest Diabetes Conference, June 6-10, 2008 CV Therapeutics' Anti-Ischemic Therapy Ranexa(R) Significantly Reduces Cardiac Chest Pain Symptoms and Recurrent Ischemia in MERLIN-TIMI 36 Patients With Angina ISTA Pharmaceuticals Announces Results of Clinical Trial of Xibrom QD (Once-Daily) Formulation Medicure Announces MEND-CABG II Study Results at the American College of Cardiology Annual Scientific Session

April 2

Pfizer Announces Discontinuation of Phase III Clinical Trial for Patients with Advanced Melanoma Iodixanol vs Iopromide Study Abstract Presented at American College of Cardiology 2008 Kamada Announces That It Had Successfully Met the Primary Endpoint in Its US Phase III Clinical Trial with Intravenous AAT MediciNova to Present Additional Clinical Data Demonstrating Potential Neuroprotection Benefits of MN-166 in Multiple Sclerosis At the 18th Meeting of the European Neurological Society Optimer Pharmaceuticals Announces Peer-Reviewed Publication of OPT-80 Phase 1 Clinical Results for the Treatment of Clostridium Difficile Infection Clinical Update - Debio 0614 (Istaroxime) in Acute Heart Failure Alfacell Updates Status of ONCONASE(R) Phase III Clinical Program Drug Does Not Appear to Reduce Risk of Heart Attack or Death Following Coronary Artery Bypass Graft Surgery Mixed Results in Clinical Trial of Weight Loss Drug Rimonabant on Slowing Progression of Coronary Disease Mayo Clinic Proceedings Examines a Possible Link Between Bacteria Found in the Human Digestive System and Obesity Bio-Rad Releases Poster That Describes Transfection Of Primary and Difficult-to-Transfect Cells Study Suggests Antiretroviral HIV Drug Linked to Increased Risk of Heart Attack One Of The World's Largest Heart Disease Studies Reveals How Thousands Of Heart Attacks And Strokes Could Be Prevented Every Year Pantec Biosolutions unveils preclinical data for novel transdermal drug delivery platform Mayo Clinic Identifies Infection Risks for Patients with Inflammatory Bowel Disease

April 4

Affymax and Takeda Report Long-Term Safety and Effectiveness Data of Hematide in Chronic Renal Failure Patients With Anemia Inspire Announces Poster Presentation at American Society of Cataract and Refractive Surgery Annual Symposium Data From Ortho Biotech-Sponsored Studies to be Presented at National Kidney Foundation 2008 Spring Clinical Meetings AMAG Pharmaceuticals, Inc. to Present Additional Positive Results from Phase III Studies of Ferumoxytol as an Intravenous Iron Replacement Therapeutic at National Kidney Foundation Spring Clinical Meetings Medicure Comments on Positive Aggrastat Results Presented at the American College of Cardiology Annual Scientific Session Momenta Pharmaceuticals Announces Presentation of M118 Phase 1 Results At the American Society for Clinical Pharmacology and Therapeutics Annual Meeting Prostate Cancer DNA Vaccine Results in Higher T-Cell Response When Delivered via Inovio Biomedical's Electroporation Delivery System Vaccine Induced Inflammation Linked to Epidemic of Type 2 Diabetes and Metabolic Syndrome Cystic Fibrosis Trial In Children Returns Positive Data ACADIA Pharmaceuticals to Present Preclinical Data on ACP-104, ACP-105 and Its Muscarinic Discovery Program at Experimental Biology 2008 Meeting Amgen's Oncology Pipeline Data Highlighted at Upcoming Scientific Meeting Neutropenia: Biosimilar Product from India Moves One Step Closer to European Market

April 7

Cyclacel Pharmaceuticals Announces Multiple Presentations at American Association of Cancer Research Annual Meeting MediciNova Reports Clinical Results From Two-Year Phase II Clinical Trial of MN-166 in Multiple Sclerosis EpiCept Announces Positive Clinical Data from EPC2407 Phase I Cancer Trial Ardea to Present Data on HIV Non-Nucleoside Reverse Transcriptase Inhibitor and Two MEK Inhibitors at Upcoming Medical Conferences Parion Sciences Announces Phase I Clinical Results for Novel Dry Mouth Treatment Biovitrum's Unique Neuropathic Pain Compound is Very Safe and Shows Positive Effect TaiGen Announces Positive Data From the Phase II Study of Nemonoxacin (TG-873870) in Community-Acquired Pneumonia Specialized Genasense Clinical Trials Featured at AACR Meeting Recent siRNA Research Publications Support Silence Therapeutics Combined Development Approach Urigen Announces Early Closure of URG101 Phase II Clinical Trial based on Positive Interim Analysis Results NovaDel Announces Positive Data from Pilot Pharmacokinetic Study Comparing Tizanidine Oral Spray to Zanaflex Tablets H1N1 Influenza Virus With Highest Replikin Count Since the 1918 Pandemic Identified in the U.S. and Austria Pluristem's Second Pre-Clinical Study in Ischemic Stroke Shows Statistically Significant Advantages in Functional and Anatomical Recovery MediciNova Reports Clinical Results From Two-Year Phase II Clinical Trial of MN-166 in Multiple Sclerosis MediGene AG (DE) - MediGene Presents Details of the Excellent Clinical Efficacy Data Obtained with EndoTAG-1 in the Indication Pancreatic Carcinoma New Data On Infinity's Lead Anti-Cancer Candidates to be Presented At AACR The GI Company to Present Phase I & II Oral Mucositis Data at MASCC / ISOO Annual Meeting

April 8

Antisoma plc (UK) - Data on AS1411 action in breast cancer cells published in Cancer Research Rigel's R788 Shows Preclinical Activity in Type 1 Diabetes Model Preclinical Data on ARIAD's Novel Investigational mTOR Inhibitor, Deforolimus, to Be Presented at the AACR Annual Meeting Metabasis Therapeutics Presents the Discovery of Its Second-Generation FBPase Inhibitor, MB07803, at the 235th American Chemical Society National Meeting ImmunoGen, Inc. Announces Presentations at the American Association for Cancer Research 2008 Annual Meeting GTx Announces Upcoming Presentation of Toremifene Citrate 80 mg Phase III ADT Clinical Trial Results MAP Pharmaceuticals Reports Positive Results From Phase 2a Clinical Trial of Combination Therapy in Adult Asthmatics ACZ885, a New Biological Drug in Development, Shows Potential in Treating Serious Life-long Autoinflammatory Diseases Phase III MS Neuropathic Pain Trial Preliminary Results Telik Announces Preclinical Presentations at AACR Annual Meeting New Clinical Data on AVEO Pharmaceuticals' Investigational Triple VEGFR Small Molecule Inhibitor AV-951 to be Presented at AACR Annual Meeting ImQuest Scientists Present Important HIV Microbicide Development Results at Microbicides 2008 in Delhi, India Combination Drug Therapy May Hold the Key to Reversing Type 1 Diabetes Critical Therapeutics Completes Phase I Clinical Trial of the R(+) Isomer of Zileuton Sirion Therapeutics Highlights Pivotal Trial Results of Durezol at the American Society of Cataract and Refractive Surgery Annual Symposium

April 9

Therapeutic Vaccine Company Inovio Biomedical Demonstrates Utility of Its Electroporation Delivery Technology as Potent Vaccine Adjuvant Cytopia Presentation on JAK2 Inhibitor at American Association for Cancer Research Poniard Pharmaceuticals Announces Presentation of Clinical Data From Picoplatin Phase 2 Small Cell Lung Cancer Trial to be Presented at 1st IASLC-ESMO European Lung Cancer Conference Sunesis Pharmaceuticals to Present Non-Clinical Data at the Annual Meeting of the American Association for Cancer Research Barrier Therapeutics Announces Positive Results in Reducing Itch Symptoms With Novel Oral Antihistamine Agent Hivenyl Aeras, Crucell and South African Tuberculosis Vaccine Initiative Announce Encouraging Preliminary Results of Tuberculosis Vaccine Clinical Trial in South Africa Idera Pharmaceuticals to Present Preclinical Data of its Toll-Like Receptor-Targeted Compounds at AACR Meeting Nektar Terminates All Negotiations With Potential Partners for Inhaled Insulin; Increased Number of Lung Cancer Cases Observed in Ongoing Clinical Studies of Inhaled Insulin Patients Nuvelo Announces Presentations on NU206 and rNAPc2 at 2008 American Association for Cancer Research Annual Meeting Curis Announces Presentations at American Association for Cancer Research Annual Meeting 2008 Xencor to Present New Data from CD19 Program at Upcoming Scientific Meetings Intra-Cellular Therapies Announces the Discovery of Potent Antidepressant Activity in ITI-007/ITI-722 PharmAthene's Recombinant Butyrylcholinesterase (rBChE) May Play A Neuroprotective Role in Alzheimer's Disease Seattle Genetics Highlights SGN-70 at AAI Annual Meeting EpiCept Announces Multiple Presentations on ASAP Technology at American Association of Cancer Research Annual Meeting NSL-043 Achieves Phase I Trial Success Kalos Therapeutics Data Confirming Anti-Cancer Effect of Naturally Occurring Heart Hormones Presented at Experimental Biology 2008 Symposium Arpida Invited to Present Data on Iclaprim at Scientific Conference Oncolytics Biotech Inc. Reports Positive Interim Results of U.K. Combination REOLYSIN(R) and Carboplatin/Paclitaxel Trial Summit Presents the Benefits Zebrafish Bring to Drug Discovery and Development at Two International Conferences Physicians and Patients Nationwide Discuss Controversial Results of Recent Cholesterol Lowering Study Enzon to Present Preclinical Data On HIF-1alpha antagonist at AACR Experimental Treatment for Type 1 Diabetes Patients Shows Promise

April 10

Inhibiton Therapeutics' Researcher to Present at American Association for Cancer Research Annual Meeting BTG Reports Positive Results from First Study Investigating BGC20-0166 in Obstructive Sleep Apnoea Patients Oncothyreon Announces Data from Multiple Small Molecule Programs to be Presented at American Association of Cancer Research Annual Meeting MedImmune Presents Data Highlighting its Progressive Oncology Portfolio at Annual Meeting of the American Association For Cancer Research Enanta Reports New Macrolide-Related Drug Class, Bicyclolides, to Combat Hospital and Community Acquired Superbug Infections, Including MRSA Nektar Therapeutics to Present Positive Data at Upcoming Medical and Scientific Meetings MannKind Addresses Pfizer's Announcement Regarding Exubera Further Research on Resveratrol Shows Promise for Treatment of Pancreatic Cancer Post-exposure Vaccination with Imvamune Protects Against Lethal Poxvirus Infection Haemacure Discloses Positive Results Of a Preclinical Study of Its Fibrin Sealant in Adhesion Prevention and Opens a New Opportunity in a Market with a Significant Unmet Medical Need RNAi Efficacy Against ALS (Lou Gehrig's Disease) in a Research Model Published in Peer-Reviewed Journal; RXi Pharmaceuticals Exclusive Licensee of Research Copaxone Significantly Reduced Annual Relapse Rates and Stabilized Disease Progression in Relapsing Remitting Multiple Sclerosis Patients Failing Interferon Treatment Antipodean Pharmaceuticals Announces Completion of Phase 2 Study of Lead Compound MitoQ(R) Access Pharmaceuticals to Present New Data on ProLindac at the AACR Annual Meeting 2008 Conference

April 11

EntreMed to Highlight ENMD-2076 Kinase Inhibitor at 2008 AACR Annual Meeting Napo Announces Successful Clinical Results in Phase 2 Study of Crofelemer in Acute Adult Infectious Diarrhea Santhera Presents Clinical Efficacy Data of SNT-MC17 in DMD at the American Academy of Neurology Annual Meeting Arpida Provides Further Comments on the Pivotal Phase III Trials Algeta to Present New Preclinical Data on Cancer-Killing Effect of Alpharadin (radium-223) at AACR Vitamin K2 Linked to Lower Prostate Cancer Risk Peregrine Pharmaceuticals Announces Four Upcoming Presentations at the American Association for Cancer Research 2008 Annual Meeting Study Shows Once-yearly Aclasta Better Than Risedronate at Increasing Bone Mass in Patients with Osteoporosis Caused by Glucocorticoids Study Shows Once-Yearly Reclast Better than Risedronate at Increasing Bone Mass in Patients With Osteoporosis Caused by Glucocorticoids Ortho Biotech Oncology Research & Development Unites Johnson & Johnson Biopharmaceutical Oncology R&D Assets Biovest Media Alert: Baltimore Sun Reports on First Patient Worldwide to be Cured of Sickle Cell Disease Using Revimmune Therapy for Bone Marrow Transplant Parents Follow Pediatrician Advice on MMR Vaccinations Bayhill Therapeutics Announces Presentation of MS Drug Candidate BHT-3009 at American Academy of Neurology 60th Annual Meeting Updated Data on Reata's Two Clinical Candidates Presented at 2008 Annual Meeting of the American Association of Cancer Research

April 14

Hollis-Eden Pharmaceuticals Presents Positive Data with APOPTONE in Preclinical Bone Model of Late-Stage Prostate Cancer Vaginal Progesterone is Equally Effective in Achieving Pregnancy Outcomes as Injectable Progesterone in Donor Egg Cycles Callisto Pharmaceuticals' Interim Phase II Data of Atiprimod in Advanced Carcinoid Cancer to be presented at ASCO Conference EntreMed's Kinase Inhibitor, ENMD-2076, Presented During AACR Special Session Cell Genesys Announces Encouraging Results from Phase 1/2 Trial of GVAX Immunotherapy for Prostate Cancer in Recurrent Disease Study Shows Intradigm's RNAi Nanoplex Technology To Be Effective Systemic siRNA Delivery Platform for the Treatment of Various Cancer Models Update From Mipomersen Extended Dosing Study Continues to Show That Mipomersen Is Well Tolerated and Maintains Activity in Patients Treated for Up to 16 Months Low HER2 Expressing Breast Cancer Patients Respond Preferentially to Apthera's NeuVax New Phase III Data Confirm Phase II Findings of Advexin Efficacy U3 Pharma Achieves Preclinical Proof of Concept for U3-1287 (AMG 888) YM Biosciences Announces Presentations for Two of Its Anti-cancer Drugs at AACR Annual Meeting The International Myeloma Foundation Says Revlimid Meets Important Quality of Life Measures The International Myeloma Foundation Says Revlimid Meets Important Quality of Life Measures BSI-201 Demonstrates Significant Tumor Growth Inhibition and Increased Survival Rates in Preclinical Ovarian Cancer Studies PG500 Series Presented at the AACR Annual Meeting in San Diego Ardea Presents Preclinical Data on Novel Next Generation Non-Nucleoside Reverse Transcriptase Inhibitors Demonstrating Potent Anti-HIV Activity Against Resistant Viruses Additive Anti-Tumor Activity of NKTR-102 in Combination With Bevacizumab Highlighted in Positive Preclinical Data Presented at AACR Meeting SuperGen's MP-470 Sensitizes Prostate and Breast Cancer Cells to Erlotinib Karmanos Researchers Find Non-Toxic Agents Added to Conventional Chemotherapy Decrease Survival of Colon Cancer Cells Nuvelo Announces Preclinical Data for NU206 Demonstrating Potent Therapeutic Activity in Oral Mucositis Models Alfacell's Onconase Shows Potential as Radiation Sensitizer for Lung Cancer Treatment TransMolecular Unveils First Data on TM601 Anti-Angiogenic Mechanism-of-Action at AACR Annual Meeting Curis Announces Preclinical Efficacy Data for CUDC-101 at AACR Annual Meeting 2008 ArQule Summarizes Abstracts Presented at AACR ArQule Summarizes Abstracts Presented at AACR Nuvelo Announces Preclinical Data for NU206 Demonstrating Potent Therapeutic Activity in Oral Mucositis Models Stem Cells From Menstrual Blood Show Therapeutic Potential Novelos Therapeutics and MUSC Present Poster at 2008 AACR Annual Meeting PhytoMedical Expands Anti-Cancer Research with Important Efficacy Tests Pluristem's PLX Cells Show a Statistically Significant Advantage in a Pre-Clinical Study in the Multiple Sclerosis Model AtheroGenics Announces Encouraging Interim Results Immunomedics Reports Veltuzumab Enhances Radioimmunotherapy With Epratuzumab in Lymphoma Model Pharmacyclics Announces Preclinical Results Supporting Development of Its Novel Btk Inhibitor in Immune Mediated Diseases Curis Announces Preclinical Efficacy Data for CUDC-101 at AACR Annual Meeting 2008 Preclinical Study Presented at AACR Annual Meeting Shows Broad Anti-Cancer Potential of Peregrine's anti-PS Vascular Targeting Antibodies Micromet Demonstrates That the Antibodies in Commercial Products Herceptin, Erbitux, Vectibix and Xolair Can Be Converted Into Highly Potent, T Cell- Engaging BiTE Antibodies Micromet Shows Feasibility of Subcutaneous Delivery of BiTE Antibody in Preclinical Primate Study Micromet Presents Safety and Efficacy Data from Primate Studies With Two New BiTE Antibodies Developed for Treatment of Leukaemia and Melanoma Semafore's PI3 Kinase Inhibitor SF1126 is a Vascular Targeted Conjugate in Phase I Clinical Trials in Solid Tumors and Multiple Myeloma Bionovo Identifies and Describes ER-beta Selective Compounds for the Treatment of Vaginal Dryness Calorie Restriction Limits and Obesity Fuels Development of Epithelial Cancers Cell Genesys Reports Preclinical Data Demonstrating Superior Anti-Tumor Immunity for Multiantigen Compared to Single-Antigen Immunotherapies

April 15

Spectrum Pharmaceuticals Presents Data on SPI-1620, a Novel Adjunct to Chemotherapy, at the American Association of Cancer Research Meeting Arius Presents New Findings for Anti-cancer Antibody Programs at AACR Oncolin Therapeutics Announces Its Lead Technology Has Shown to Be Effective in Treating Cancer in Animal Models Genentech and Biogen Idec Announce Top-Line Results from a Phase II/III Clinical Trial of Rituxan in Primary-Progressive Multiple Sclerosis Callisto Pharmaceuticals Announces Presentation on SP-304 at the 3rd International Congress on Natural Peptides to Drugs Pharmacopeia Announces Upcoming Late-Breaker Presentation of Phase 2a Results for Its First-in-Class Investigational DARA Compound, PS433540 Oncothyreon's PX-478 Enhances Antitumor Effects of Radiation Therapy in Preclinical Models of Pancreatic and Brain Cancer Sunesis Pharmaceuticals Presents Nonclinical Data on SNS-595 at the Annual Meeting of the American Association for Cancer Research AVEO Pharmaceuticals’ Novel Triple VEGF Receptor Inhibitor Shows Tumor Regression in Patients with Advanced Renal Cancer Sangamo BioSciences Announces Presentation of Data on ZFP Therapeutic for Glioblastoma at American Association for Cancer Research (AACR) Meeting Cancer Prevention: Stopping Cancer Before It Can Start Active Biotech (SE) - Preclinical data presented for Active Biotech's Anyara technology Transcept Pharmaceuticals: Study of Intermezzo by Leading Sleep Expert Published in Human Psychopharmacology Oculus Innovative Sciences Announces Publication of Microcyn Technology Diabetic Wound Study in Journal of College of Physicians and Surgeons Pakistan Bionovo to Present Recent Findings of BN107 and BN108, Its Anticancer Agents, at the American Association of Cancer Research ICLL: Investigational vaccine against JE shows excellent safety and immunogenicity in Phase II trials in children Positive Results from Phase I Clinical Trial of SMT D002 for the Treatment of Seborrhoea, a Primary Cause of Acne Data Presented at AACR Annual Meeting Shows Bavituximab Equivalent Plus Docetaxel Reduces Tumor Growth By Up to 95% and Halts Metastasis in a Model of Hormone-Refractory Prostate Cancer Aeolus Pharmaceuticals' AEOL 10150 Protects Lungs from Fractionated Radiation; Reduces Angiogenesis and Inflammation Optimer Pharmaceuticals Sponsors ECCMID Symposium on Clostridium Difficile-Associated Disease: Current Treatments and Challenges Inhibitex Presents Encouraging Phase I Data on FV-100 At 21st International Conference on Antiviral Research Halozyme Therapeutics Presents Pre-Clinical Studies of Systemic Delivery of Pegylated rHuPH20 Enyzme in Prostate Cancer Models at American Association for Cancer Research Conference InNexus Biotechnology Presents Proof of Principle Data at AACR Annual Meeting 2008 SkyePharma Announces Positive Results of Flutiform Paediatric Study Arius presents new findings for anti-cancer antibody programs at AACR Patients With Early Parkinson's Disease Show Better Symptom Control and Improvements in Daily Activities with Stalevo Than Levodopa/Carbidopa Xanthus Presents Data Supporting Distinctive Mechanism of Action for Xanafide Callisto Pharmaceuticals Announces Presentation on SP-304 at the 3rd International Congress on Natural Peptides to Drugs ANX-530 Demonstrates Equivalent Pharmacokinetics to Navelbine(R) in a Registrational Bioequivalence Clinical Study Abraxis BioScience Presents New Preclinical Data Demonstrating Eradication of Large Orthotopic Breast Tumors and Metastasis with Combined nab-Paclitaxel (Abraxane) and Bevacizumab (Avastin) Therapy Seattle Genetics Presents Preclinical Data on its Antibody-Drug Conjugate Technology and SGN-33 Program at AACR Medarex Reports Interim Data from Ongoing Ipilimumab Combination Phase 1 Studies in Prostate Cancer at American Association for Cancer Research Meeting Amgen Presents Preclinical and Clinical Data from Oncology Programs Drugs in the Pipeline: New Therapies that Could Change Treatment Strategies Medivation's Dimebon Significantly Improved Daily Function in Alzheimer's Disease Patients, Resulting in Reduced Need for Caregiver Assistance Immunotherapy: Enlisting the Immune System to Fight Cancer New Data Published in Circulation Showed an Increase in HDL Cholesterol Levels with Actos (pioglitazone HCl) Nymox Nears Completion of Latest U.S. Study of NX-1207 for Benign Prostatic Hyperplasia Peregrine Researchers Present New Preclinical Data at AACR Annual Meeting Confirming Unique Anti-Tumor Mechanism of Bavituximab Advaxis Discloses Clinical Results of the First Ever Live Listeria Monocytogenes Trial Paloma Pharmaceuticals to Present at the American Association for Cancer Research Oncolytics Biotech Inc. Collaborators Present Reovirus Research for Pediatric Sarcomas at AACR Annual Meeting Preclinical Study Shows CTI's Brostallicin's Cancer-Killing Ability Based on Genetic Profiling Preclinical Study Presented at AACR Annual Meeting Shows Peregrine's Anti-PS Immunocytokines Can Generate Protective Immune Responses in a Highly Aggressive Breast Cancer Model Pharmacyclics Reports Multiple Presentations at AACR on Its HDAC and Selective HDAC Inhibitors ARIAD Presents Preclinical Deforolimus Data at American Association for Cancer Research Meeting in Support of Clinical Initiatives Study Shows that High-Dose, High-Frequency Interferon Produces no Additional Benefit on Efficacy Compared to Avonex (interferon beta-1a) in Patients with Relapsing-Remitting Multiple Sclerosis (RRMS) Cell Genesys Reports Data on an Association Between Immune Response and Anti-Tumor Activity in Patients Receiving GVAX Immunotherapy for Prostate Cancer and Ipilimumab (MDX-010) Seattle Genetics Presents Preclinical Data on its Antibody-Drug Conjugate Technology and SGN-33 Program at AACR First Fracture Prevention Study in Men Receiving ADT for Prostate Cancer Presented at AACR Annual Meeting GenVec Presents New Research on TNFerade Oncolin Therapeutics Lead Cancer Technology is Being Presented Today at the Annual Meeting of The American Association for Cancer Research Biogen Idec and Elan Present New Tysabri Data at the 60th Annual Meeting of the American Academy of Neurology Opexa Therapeutics Presents Tovaxin Phase I/II Data at the American Academy of Neurology 60th Annual Meeting Oncolytics Biotech Inc. Collaborators Present Reovirus Research for Multiple Myeloma at AACR Annual Meeting

April 16

Data Presented at AAN Show That Lacosamide Significantly Reduced Pain and was Generally Well Tolerated in Patients With Diabetic Neuropathic Pain EntreMed Presents MKC-1 and ENMD-1198 Preclinical Data at AACR Annual Meeting ImmuneRegen Releases Results from UMDNJ Study Confirming Homspera's Adult Stem Cell Activity Oncolytics Biotech Inc. Announces Gene Therapy Publication on Reovirus Treatment for Melanoma Geron Presentations at the AACR 2008 Annual Meeting Graceway Pharmaceuticals Reports Study in British Journal of Dermatology: Patients Treated with ALDARA Experienced Higher Levels of Histological and Sustained Clearance for Actinic Keratosis (AK) than Patients in two Other Common AK Treatments Lorus Therapeutics Presents New Findings for the Anticancer Drugs LOR-253 and LOR-2040 FTY720, a Novel Oral Therapy in Development for MS, Shows Sustained Benefits for the Majority of Patients After Three Years of Treatment Sirtris Scientific Advisory Board Co-Chairs Publish First In-Vivo Data Showing SIRT1 Enzyme Can Suppress Tumor Development Data for Oncothyreon's PX-12 and PX-866 Presented at AACR Annual Meeting Medarex Reports Preclinical Data on Multiple Antibody-Drug Conjugate Candidates at American Association for Cancer Research Meeting Amgen Presents Preclinical and Clinical Data from Oncology Programs Amgen's Oncology Pipeline Data Highlighted at Upcoming Scientific Meeting Lyrica Reduced Pain of Fibromyalgia in Patients Regardless of Symptoms of Anxiety or Depression Preclinical Data Highlighting Potential of Retaspimycin in Treating Non-Small Cell Lung Cancer With Acquired Drug Resistance Presented by Infinity and MedImmune At AACR Genmab A/S - Company Announcement: Novel Insights into HuMax-EGFr Mechanisms of Action Published in PNAS Laboratory Study Shows Naturally Occurring Antibodies Contained in Gammagard Liquid May Bind to the Primary Culprit for Alzheimer's Disease AACR presentation illustrates broad potential of Antisoma's AS1411 in blood cancers Novavax Reports Positive Results from Preclinical Studies of its VLP-based Trivalent Seasonal Influenza Vaccine Candidate Sunesis Pharmaceuticals Reports Data from Nonclinical Studies of SNS-032 at the Annual Meeting of the American Association for Cancer Research VioQuest Pharmaceuticals' Novel Akt Inhibitor VQD-002 is Synergistic with Various Cancer Therapies in Preclinical Studies Halozyme Therapeutics Presents Findings on Combinations of rHuPH20 Enzyme With Bisphosphonates at the American Association for Cancer Research Conference Medarex Reports Preclinical Data on Multiple Antibody-Drug Conjugate Candidates at American Association for Cancer Research Meeting ImQuest Presents New Anti-HIV Drug and Topical Microbicide Development Results on Lead Pyrimidinedione Products IQP-0410 and IQP-0528 University of Virginia Study Shows That Lisofylline Reduces Obesity-Related Inflammation and Insulin Resistance Medicure Announces Presentation of Phase II Matched Results at Cardiovascular Conference Acadia Pharmaceuticals to Present Data from Its Phase II Trial with Pimavanserin for Parkinson's Disease Psychosis at the 60th American Academy of Neurology Annual Meeting Xanthus' Symadex Reverses Disease in Preclinical Mouse Models of Multiple Sclerosis Pharmacyclics' Novel Factor VIIa Inhibitor Demonstrates Potential Inhibition of Tumor Growth in Multiple Types of Cancer ZIOPHARM Presents Positive Data from Phase II Study of Darinaparsin in Advanced Hematological Malignancies at AACR 2008 Annual Meeting SuperGen Identifies Lead PIM Kinase Inhibitor, SGI-1776, That Causes Tumor Regression in AML Xenograft Models Cyclacel Pharmaceuticals presents insights into the mechanisms of its cell cycle inhibitor drugs Multiple Myeloma Research Consortium and Sunesis Pharmaceuticals Present Data On SNS-032 At American Association of Cancer Research Annual Meeting OSI Pharmaceuticals Summarizes Data Presented at the Annual Meeting of the American Association for Cancer Research Celator Pharmaceuticals Successfully Uses Nanoparticles to Administer Hydrophobic Drug Combinations Schering-Plough Announces Imperfect Contraceptive Use Impacts Women's Emotional Well-Being Reclast better than Actonel at increasing bone mass in GIO patients High Cholesterol in Your 40s Increases Risk of Alzheimer's Disease Muscle Mass May Not Fully Explain Higher Creatinine in Blacks with Kidney Disease Bayhill Therapeutics Presents Data From a Phase II Trial of BHT-3009 in Multiple Sclerosis at American Academy of Neurology 60th Annual Meeting Novel Drug Delivery Methods: Getting Drugs to Tumors Quickly and with Less Toxicity

April 17

Arpida Provides Comprehensive Overview of Pivotal Phase III Trial Data Methylgene Presents Preclinical Data for Its Multi-targeted (C-Met) Kinase Inhibitor, Mgcd265, at AACR Annual Meeting Medarex Reports Phase 1/2 Clinical Data of MDX-060 in Lymphoma at American Association for Cancer Research Meeting Lexicon's Drug Candidate for Rheumatoid Arthritis, LX2931, Shows Positive Results in Phase 1 Clinical Trial Kosan Presents Preclinical Data on Novel Third-Generation Hsp90 Inhibitors at AACR Data Presented at the 60th Annual Meeting of the American Academy of Neurology Offers Additional Support for Plasma Exchange as a Potential Tool to Accelerate TYSABRI(R) Removal Protox Announces Positive Long-term Data from BPH Study Early Treatment with Copaxone Significantly Delayed Progression to Clinically Definite Multiple Sclerosis 2nd Alzheimer¹s vaccine by AFFiRiS Positive Results in First Clinical Study with Anti Diabetes Compound Kb3305 Access Pharmaceuticals Announces New Data on Angiolix Spectrum Pharmaceuticals Presents Data on Lucanthone, a Novel Anticancer Drug, at the Meeting of the American Association of Cancer Research Sirtris Announces SRT501 Lowers Glucose in Twice-Daily Dosing Clinical Trial; Study Suggests Dose Response for Proprietary Formulation of Resveratrol in Type 2 Diabetics Results from Largest Statin Study of Patients with Alzheimer's Disease Show Lipitor Has No Significant Impact on Disease Schering-Plough Highlights PegIntron and Boceprevir Data Presentations at European Association for the Study of the Liver (EASL) Annual Meeting Kosan Presents Preclinical Data on Nuclear Export Inhibitors, Novel Anticancer Agents, at AACR New Data Show Treatment of Multiple Sclerosis (MS) with Avonex (interferon Beta-1a) Enhances Quality of Life NexGenix Pharmaceuticals Presents Data on a Novel Small Molecule Inhibitor of Heat Shock Protein 90 (Hsp90) at the Annual Meeting of the American Association for Cancer Research (AACR); Scientific Advisory Board Chairman Tyler Jacks Named President-elect of AACR Pharmaceutical Ghostwriting Trend Mars Credibility of Research and Negatively Impacts Patient Safety New Hope for Migraine Sufferers: Optinose Nasal Delivery of Sumatriptan Proves as Effective as Invasive Subcutantaneous Injection Nymox Announces Clinical Study Presentation on BPH Drug at American Urological Association Meeting Data Presented at the American Academy of Neurology Show XP13512/GSK1838262 Significantly Improved Symptoms of Moderate-to-Severe Primary Restless Legs Syndrome Idera Pharmaceuticals Presents Data from Study of Toll-Like Receptor Antagonist in Preclinical Model of Multiple Sclerosis

April 18

Anthera Presents Data on Varespladib at ATVB Meeting Telik Presents Preclinical Data at 99th Annual Meeting of the American Association for Cancer Research Isotechnika's Canadian Phase 3 Psoriasis Trial Published in The Lancet Anadys Pharmaceuticals Presents Data on ANA598, a Non-Nucleoside Inhibitor of the HCV Polymerase, at the 21st International Conference on Antiviral Research Copaxone Significantly Reduced Brain Atrophy and Tissue Loss over Five Years in Treatment-Naive Relapsing-Remitting Multiple Sclerosis Patients Isis Reports Reduction of apoB-100 Levels in a Murine Model Resulting in Up to 92% Reduction of Atherosclerosis Herceptin Helps Eradicate HER2-Positive Breast Tumours When Given Before Surgery Using Anticholinergic Drugs May Increase Cognitive Decline in Older People Data Presented at AAN Support Potential for Adjunctive use of Intravenous Lacosamide as Short-Term Replacement for Oral Treatment in Partial Epilepsy Advaxis' Listeria Monocytogenes-Based Vaccine Garners National Media Attention FASgen, Inc. Presents Ovarian Cancer Efficacy and Toxicology Data to the American Association for Cancer Research Novel Xeloda Dosing Schedule May Offer Well-Tolerated Alternative for Treatment of Advanced Breast Cancer

April 21

Medivation's Dimebon Significantly Improved Thinking and Memory in Alzheimer's Disease Patients Over One Year New scientific data on ceftobiprole and isavuconazole will be presented at ECCMID Genentech Provides Update on ''AVAiL'' Phase III Study of Avastin Plus Chemotherapy in First-Line, Advanced, Non-Squamous, Non-Small Cell Lung Cancer Targanta Announces Highlights of Oritavancin Data to Be Presented at the 18th ECCMID Targanta Announces Launch of Oral Oritavancin Development Program against C. Difficile Bacterial Infection Graceway Pharmaceuticals Reports Study in New England Journal of Medicine: Aldara (imiquimod) Cream, 5% demonstrated a reduction in lesion size in patients with vulvar intraepithelial neoplasia New antibiotic class proves effective against MRSA Sirion Therapeutics Preclinical Studies: Two New Potential Advances in Treatment of Retinal Diseases to be Presented at ARVO ACORN Presents Findings of Collaborative Metastatic Colorectal Cancer Research Liver Phase I Abstract to Be Presented At WCIO 2008 & Best Of ASCO Interim Analysis of Phase I/II Study of Rexin-G Confirms Efficacy With No Dose Limiting Toxicity in Metastatic Pancreatic Cancer Interim Analysis of Phase I/II Study of Rexin-G Confirms Efficacy with No Dose Limiting Toxicity in Metastatic Pancreatic Cancer; Second Phase Opens with Higher Dose Regimens BioAlliance Pharma Announces Preliminary Results from the Pivotal US Phase III Trial for Loramyc High-Dose Lipitor Reduced the Risk of Heart Attack and Stroke in Patients with Chronic Kidney Disease

April 23

Telaprevir-Based PROVE Studies Show Significantly Higher SVR Rates in Treatment-Naive Genotype 1 Hepatitis C Patients in Half the Time of Current Treatments La Jolla Pharmaceutical Announces Positive 12-Month Interim Antibody Data and Provides Update for Ongoing Riquent(R) Phase 3 'ASPEN' Lupus Trial Inspire to Discontinue Development of Epinastine Nasal Spray Oral PBI-1402 Demonstrates Significant Activity in Chemotherapy-Induced Anemia Phase II Clinical Trial Poniard Pharmaceuticals Announces Final Picoplatin Data from Phase 2 Small Cell Lung Cancer Trial Demonstrating Survival Benefit Idenix Pharmaceuticals Presents Positive Preclinical Data on HCV Programs at The Annual Meeting of The European Association for the Study of the Liver (EASL) Abraxis BioScience Reports Promising Clinical Data in Advanced Pancreatic Cancer Using a Combination of nab-Paclitaxel (Abraxane) and Gemcitabine (Gemzar) Results from Renzapride Phase III Clinical Trial Starpharma Holdings Studies Show That VivaGel Inhibits Clinically Relevant Strains Of Human Papillomavirus (HPV) In Laboratory Tests Romark Announces Presentation of New Data for Nitazoxanide in Chronic Hepatitis C at EASL 2008 Spectrum Pharmaceuticals Provides an Update on Ozarelix in BPH Amkor Pharma, Inc. Completes All Clinical Activities for Its Phase I Study of Neu2000KL for Treatment of Acute Brain Injury Aeolus Pharmaceuticals' AEOL 10150 Provides Significant Protection of Lungs and Skin in Animal Studies of Mustard Gas Exposure Oncolytics Biotech Inc. Announces Journal of Immunology Publication on Reovirus Activation of Dendritic Cells Study Finds Cisplatin Less Effective Than Standard Treatment for Patients With Anal Cancer

April 24

EPIX Pharmaceuticals Announces Positive Results From Re-Read of Vasovist Phase 3 Images Medivir: First Data on TMC435350 in Patients with Hepatitis C Who Have Failed Previous Treatment Shows Antiviral Activity OctoPlus presents Positive Locteron Phase IIa Study Results at EASL Conference Valeant Pharmaceuticals Highlights Taribavirin Phase IIb Data Presentation at European Association for the Study of Liver (EASL) Annual Meeting Gilead Announces 72-Week Data From Two Pivotal Phase III Studies Evaluating Viread for the Treatment of Chronic Hepatitis B Resolvyx to Present Data on Novel Resolvin Drug Candidates for Eye Disease at ARVO Annual Meeting International Research Team Publishes Details of TB4's Cardioprotective Effects in Ischemia-Reperfusion Study NAFLD AND NASH Linked to Metabolic Syndrome and Cardiovascular Disease Vertex Announces Positive Interim Results with Telaprevir-based Therapy in Genotype 1 Chronic Hepatitis C Patients who Failed to Achieve SVR with Previous Pegylated Interferon & Ribavirin Treatment Antipodean Pharmaceuticals Announces Results of Phase 2 Study of Lead Compound MitoQ(R) SurModics to Present at the 2008 Association for Research in Vision and Ophthalmology Meeting Nventa Completes Safety Evaluation on Final Cohort in HspE7 Phase 1 Cervical Dysplasia Trial

April 28

Roxro Pharma Announces Positive Clinical Proof of Concept Results for Novel Intranasal Migraine Treatment Regeneron and Bayer HealthCare Announce Encouraging 32-Week Follow-Up Results from a Phase 2 Study of VEGF Trap-Eye in Age-Related Macular Degeneration Interim Results from Boceprevir Phase II Study in Genotype 1 Treatment-Naive Hepatitis C Patients Presented At EASL MorphoSys Announces Completion of First Dosing in Phase 1 Trial for MOR103 Program Clinical Update - Debio 025 in Hepatitis C Baraclude (Entecavir) Treatment Resulted In Greater Viral Load Suppression Compared to Adefovir at 96 Weeks In Antiviral-Naive Adult Chronic Hepatitis B E-Antigen Positive Patients Cara Therapeutics Initiates Phase 1 Clinical Trial of Novel Analgesic, CR845 Drug Combo Could Lower Diabetes Complications and Costs Isotechnika's Strategic Partner to Highlight Both Topical and Polymer Delivery Technologies Utilizing Voclosporin Cosmetic Dermatology Publishes Data Highlighting the Benefits of CLENZIderm M.D. Systems for Acne Kaiser Permanente Study Finds Diabetes Doubling Before Motherhood Alnylam and Collaborators Publish Research on the Immunostimulatory Properties and Mechanisms of Certain siRNAs in Mammalian Cells Lux Biosciences' Presentations at ARVO Highlight Both Topical and Polymer Delivery Technologies Targeting Chronic Inflammatory Ocular Diseases Alnylam and Collaborators at MIT Publish Research on the Discovery of 'Lipidoids', a Novel Class of Lipid-Based Molecules for the Delivery of RNAi Therapeutics Metabasis Therapeutics Announces Positive Results in the Phase 2a Clinical Trial for MB07803, Its Product Candidate for the Treatment of Type 2 Diabetes Aida Pharmaceuticals, Inc. Announces Update on Progress of Rh-Apo2L Testing Pluristem to Present at LD MICRO Conference April 29, 2008 Basic Science Discoveries Yield Progress in Hepatology Final Results of Ideal Study Presented at Annual Meeting of the European Association for the Study of the Liver (EASL) Roche's Investigational Hepatitis C Polymerase Inhibitor, R1626, Demonstrated Significant End-of-Treatment Response in Phase IIa Study Gene Therapy Provides Vision to People who Were Nearly Blind Three Studies Presented at 43rd EASL Showed Higher SVR for Pegasys (Peginterferon Alfa-2a) Plus Ribavirin Than Peginterferon Alfa-2b Plus Ribavirin in Treating Hepatitis C Dr. Calvin Grant Presents Results from Xibrom Combination Therapy with Lucentis at the 2008 Annual Meeting of the Association for Research in Vision and Ophthalmology (ARVO) Bayer HealthCare and Regeneron Announce Encouraging 32-week Follow-Up Results from a Phase 2 Study of VEGF Trap-Eye in Age-related Macular Degeneration Fourteen Abstracts Featuring MedImmune's Influenza and RSV Therapeutic Areas to Be Presented at Pediatric Academic Societies Annual Meeting Titan Pharmaceuticals Announces Spheramine(R) Presentation at 76th Annual American Association of Neurological Surgeons (AANS) Meeting

April 29

Imaging Results From the ADAGIO-LIPIDS Reveal That Effects of Rimonabant on Cardiometabolic Risk Profile Include Loss of Visceral Fat and Mobilization of Liver Fat Rigel's R788 Slows Progression of Murine Lupus in Preclinical Studies Biovitrum Presents Detailed Results from Clinical Neuropathic Pain and Glaucoma Projects Alexza Announces Positive Phase 1 Results With AZ-007 (Staccato Zaleplon) Orexo Reports Positive Results from Phase I Study for OX19 Medarex Announces Presentations at Annual Meeting of the American Society of Clinical Oncology Summit Reports Progress of Duchenne Muscular Dystrophy Programme at International Conference Nuvelo Announces Positive Proof-of-Concept Data With Anticogulant NU172 Peregrine Pharmaceuticals Completes Patient Enrollment in First Stage of Bavituximab Phase II Breast Cancer Trial Dr. Gabriel Sosne Presents TB4 Anti-inflammation Data at ARVO Acucela Presents Preclinical Data from Retinopathy Study Demonstrating Improvement in Retinal Abnormalities Genentech and Biogen Idec Announce Top-Line Results From Phase II/III Clinical Study of Rituxan in Systemic Lupus Erythematosus Osteoporosis Drug Fosamax Linked to Heart Problem New Treatment Offers Hope for Beating Aggressive Cancers deCODE Discovers Genetic Variants Influencing Bone Mineral Density Nuvelo Announces Positive Proof-of-Concept Data With Anticogulant NU172 Synthetic Blood International Comments on JAMA Article About Hemoglobin-Based Blood Substitutes Statement From the Lupus Foundation of America Regarding the Release of Top-Line Results From a Study of Rituxan for the Treatment of Lupus

April 30

Aradigm Announces Data Showing No Occurrence of Primary Lung Cancer in Patients Treated with AERx Insulin Diabetes Management System (iDMS) Interim Analysis of Phase I/II Study of Rexin-G Confirms Efficacy Dynogen to Present Positive Clinical Data for DDP225 and DDP733 at Digestive Disease Week 2008 Conference Understanding Red Wine's Potential Benefit for Diabetes SinuNase Fast-Tracked Pivotal Phase 3 Study in Chronic Sinusitis Shows Statistically Significant Objective Evidence of Superiority of SinuNase Over Control Lavage in Severe Cases Genelabs Technologies Announces Presentation of Data on HCV NS4b Inhibitors at the Inaugural HCV Drug Discovery Meeting Phosphagenics Reports Positive Pre-clinical Results for Targeted Delivery of Lidocaine OXiGENE Announces Preclinical Data Demonstrating that the Active Metabolite of ZYBRESTAT Improves Glucose Metabolism through Similar Mechanism as a Sirtuin Agonist NovaBay Researcher Contributes Important Article to Pharmaceutical Formulation & Quality Magazine Nymox Announces New Positive Results at 54 Months in Long Term Study of NX-1207 for Benign Prostatic Hyperplasia ImmunoVaccine Technologies Patents DepoVax Vaccine Platform CureDM's Diabetes Therapy Achieves Major Development Milestone Cequent Pharmaceuticals' Johannes Fruehauf, MD, Ph.D., to be Featured Speaker at RNAi World Congress in Boston - May 2, 2008 TriMix-gel vs Viagra, Levitra, Cialis Data to Be Presented at AUA

Clinical Trial Results Archive

2005

April

More News Resources

(web3)